Generic
Amoxycillin Trihydrate (Vet)
At a glance
Amoxycillin Trihydrate (Vet) is a broad-spectrum penicillin antibiotic indicated for various bacterial infections including respiratory, skin, and urinary tract infections.
Description
Broad-spectrum aminopenicillin antibiotic inhibiting bacterial cell wall synthesis for treating susceptible bacterial infections.
Indications
Infections due to susceptible strains including ENT, lower respiratory tract, skin and soft tissue, genito-urinary tract, dental abscess, and H. pylori.
Therapeutic class
Broad spectrum penicillins
Pharmacological class
Aminopenicillin
Pharmacology
Inhibits cell wall biosynthesis, stable in gastric acid, rapidly absorbed after oral administration with wide tissue distribution.
Mechanism of action
Inhibition of bacterial cell wall biosynthesis.
Dosage
Adult: 250 mg to 500 mg three times daily. Children: 125 mg to 250 mg three times daily. Varies by indication.
Administration
Suspension can be added to milk, fruit juice, or water and taken immediately. Injection via IM or IV as specified.
Missed dose
Take as soon as remembered.
Side effects
Diarrhoea, indigestion, rash, rarely pseudo-membranous colitis.
Precautions & warnings
Monitor for superinfections with mycotic or bacterial pathogens; adjust dose in renal impairment.
Contraindications
Contraindicated in penicillin hypersensitive patients.
Drug interactions
Concurrent use with Probenecid increases blood levels; may reduce efficacy of oral contraceptives.
Food interactions
Can be taken with or without food.
Use in pregnancy
US FDA Pregnancy Category B. Use if clearly needed.
Pregnancy Category: B — always consult a doctor before taking during pregnancy.
Use in lactation
Excreted in human milk; exercise caution when administered to a lactating mother.
Pediatric use
Used in children with appropriate weight-based or age-based dosing.
Geriatric use
Use as advised by physician.
Renal / hepatic impairment
Reduce total daily dosage in renal impairment.
Overdose effects
Supportive care as needed.
Storage conditions
Keep in a dry place away from light and heat. Keep out of reach of children.
Chemical structure
Amoxycillin Trihydrate