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Benazepril

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At a glance

Benazepril — brands, prices, indication, dosage and side effects available in Bangladesh.

Description

Benazepril is used to treat hypertension (high blood pressure). This is a combination of two medicines that controls blood pressure when a single medication is not effective. It helps to lower high blood pressure and thus reduces the chances of future heart attack and stroke. You can take Benazepril at any time of day, with or without food, but it is best to take it at the same time each day. Keep taking it for as long as advised by your doctor. Even if you feel well, do not stop this medicine on your own because high blood pressure often has no symptoms. If you stop taking it, your condition may get worse. Keeping active with regular exercise, reducing your weight and eating a healthy diet will also help control your blood pressure. Follow your doctor's advice while taking this medicine. It may cause side effects like ankle swelling, headache, weakness, numbness of extremities, flushing (sense of warmth in the face, ears, neck, and trunk), and tiredness. It may also cause dizziness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. You may be asked for regular monitoring of blood pressure, kidney function, and electrolytes level while on the treatment. Before taking it, let your doctor know if you have any liver or kidney problems. Pregnant or breastfeeding women should also consult their doctor for advice before taking this medicine. You also need to tell your doctor what other medicines you are taking especially those used to treat high blood pressure or heart conditions. Benazepril is a combination of two medicines: Amlodipine and benazepril which lower blood pressure effectively. It works by relaxing blood vessels so that blood flows more smoothly and the heart can pump blood more efficiently.

Indications

• Hypertension (high blood pressure)

Mechanism of action

Benazepril, a prodrug of benazeprilat, acts by inhibiting ACE that catalyzes the conversion of angiotensin I to angiotensin II (a potent vasoconstrictor), thus leading to reduced aldosterone (a hormone that causes water and Na retention) secretion by the adrenal cortex and decreased vasopressor activity.

Dosage

Adult Dose: Oral Hypertension Adult: Initially, 10 mg once daily. Maintenance: 20-40 mg/day as a single or in 2 divided doses. Max: 80 mg/day. Patients on diuretics: Initially, 5 mg once daily. Heart failure Adult: Initially, 2.5 mg once daily adjusted according to response to max 20 mg/day. Child Dose: Oral Hypertension Child: >6 yr 0.2 mg/kg once daily. Maintenance: 0.6 mg/kg once daily. Max: 40 mg/day. Renal Dose: Renal impairment: CrCl (ml/min) Dosage Recommendation <30 Initially, 5 mg once daily. Max: 40 mg/day.

Administration

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Benazepril may be taken with or without food, but it is better to take it at a fixed time.

Side effects

Common: • Ankle swelling • Headache • Tiredness • Palpitations • Increased potassium level in blood • Sleepiness • Cough • Taste change • Flushing (sense of warmth in the face, ears, neck and trunk) • Decreased blood pressure • Upset stomach

Precautions & warnings

[UNSAFE] Benazepril may cause side effects which could affect your ability to drive. As it is advisable to exercise caution when driving with Benazepril. You have been prescribed Benazepril for the treatment of high blood pressure. Lowering blood pressure reduces chance of future heart attack & strokes. It may cause dizziness. Get up slowly when rising from a sitting or lying position. Do not take Benazepril if you are pregnant or planning for pregnancy.

Contraindications

History of angioedema due to previous ACE inhibitor treatment. Pregnancy.

Drug interactions

Additive hyperkalaemic effects w/ K-sparing diuretics, K supplements, other drugs that can cause hyperkalaemia. May increase lithium concentration and toxicity.

Food interactions

[UNSAFE] It is unsafe to consume alcohol with Benazepril.

Use in pregnancy

[CONSULT YOUR DOCTOR] Benazepril is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Use in lactation

[SAFE IF PRESCRIBED] Benazepril is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Renal / hepatic impairment

[CAUTION] Benazepril should be used with caution in patients with kidney disease. Dose adjustment of Benazepril may be needed. Please consult your doctor. Regular monitoring of blood pressure is recommended for better dose adjustment. [CAUTION] Benazepril should be used with caution in patients with liver disease. Dose adjustment of Benazepril may be needed. Please consult your doctor. Benazepril is started at a lower dose in patients with liver disease and further increased slowly with careful monitoring.

Common questions

Hypertension blood pressure pro Bp any medicine u taking Please prescribe substitute of BP medicine Amace which I was talking but now not available in Bhubaneswar Odisha. amlodepine is the salt High blood pressure continuously How much is d bp High Blood pressure, severe headache How much is bp HIGH blood pressure,over weight how much is BP Some times I had lot of hypertension Hypertension is clinically high blood pressure. Persistent high arterial blood pressure above 120/80 mm HG is termed as pre-hypertension or hypertension, but the point to be emphasized is that this rise in blood pressure is persistent. Transient increase in BP occurs in stress and anxiety and needs to be treated accordingly. High blood pressure from last one month Hows your bp now I am taking alfoo 10 mg for past 20 days and noticing high blood pressure. Does this medication cause high blood pressure? It causes low bp

⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.
Benazepril — দাম, ব্যবহার, ডোজ ও পার্শ্বপ্রতিক্রিয়া | oshudhkosh