Generic

Daratumumab

At a glance

Daratumumab — brands, prices, indication, dosage and side effects available in Bangladesh.

Description

Daratumumab is used in the treatment of multiple myeloma, which is a type of cancer of plasma cells. Daratumumab is given as an IV infusion into veins under the supervision of a doctor. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. Infusion reaction such as swollen face, lips, mouth, tongue or throat, difficulty swallowing or breathing are very common side effects. This medicine may reduce the number of blood cells (decrease white blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells while taking this medicine. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. Use of effective contraception by both males and females during treatment is important to avoid pregnancy. Daratumumab is a monoclonal antibodies, which are designed to recognise and attach to specific proteins on the surface of cancer cells. It shows its action by binding to specific cancer cells in the body and helps your immune system kills cancer.

Indications

• Multiple myeloma

Mechanism of action

Daratumumab is a monoclonal antibodies, which are designed to recognise and attach to specific proteins on the surface of cancer cells. It shows its action by binding to specific cancer cells in the body and helps your immune system kills cancer.

Administration

Your doctor or nurse will give you this medicine. Kindly do not self administer.

Side effects

Common: • Back pain • Constipation • Decreased white blood cell count (neutrophils) • Diarrhea • Dizziness • Fatigue • Fever • Infusion reaction • Insomnia (difficulty in sleeping) • Joint pain • Low blood platelets • Nausea • Breathlessness • Upper respiratory tract infection • Vomiting

Precautions & warnings

[SAFE] Daratumumab does not usually affect your ability to drive.

Food interactions

[CONSULT YOUR DOCTOR] It is not known whether it is safe to consume alcohol with Daratumumab. Please consult your doctor.

Use in pregnancy

[CONSULT YOUR DOCTOR] Daratumumab may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Use in lactation

[CONSULT YOUR DOCTOR] Daratumumab is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Renal / hepatic impairment

[SAFE IF PRESCRIBED] Daratumumab is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Daratumumab may not be needed in these patients. Please consult your doctor. [SAFE IF PRESCRIBED] Daratumumab is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Daratumumab may not be needed in these patients. Please consult your doctor.

Common questions

Please tell me the interpretation of the attach report, if possible. Also guide for further treatment process.

U r having multiple myeloma Multiple myeloma can be cured or not Yes, if diagnosed at the right stage Multiple sceloris_glatira injection 6 months can cure ? there is no curative trt in Ms; this drug lowers rate of progresion and lowers risk of disability Pus disharge from maxilla.Patient has multiple myeloma Tooth exfoliated from the jaw post which this change was noted OPG reveals radiolucency in that site Visit to a dentist for proper treatment by surgery. Report shows higher esr value what should i do. A very high ESR usually has an obvious cause, such as a severe infection, marked by an increase in globulins, polymyalgia rheumatica or temporal arteritis. A health practitioner will typically use other follow-up tests, such as blood cultures, depending on the person's symptoms. People with multiple myeloma or Waldenstrom's macroglobulinemia (tumors that make large amounts of immunoglobulins) typically have very high ESRs even if they don't have inflammationNeed to correlate clinicallyKindly consult your doctor What is LENALIDOMIDE & why should it be taken ? Lenalidomide is a anti myeloma medicine Multiple of moles covered the chin area, taking PPD injection but still, didnt found any changes Go for removal by machine by skin specialist I am diagnosed with myeloma. Is the transplantation is compulsory for me? Yes for better life

⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.