Dexrabeprazole Sodium

Dexrabeprazole Sodium is a medicine that reduces the amount of acid produced in your stomach. It is used for treating acid-related diseases of the stomach and intestine such as heartburn, acid reflux, peptic ulcer disease, and some other stomach conditions associated with excessive acid production. Dexrabeprazole Sodium is also used to prevent stomach ulcers and acidity that may be seen with the prolonged use of pain-killers. It belongs to a class of medicines known as proton pump inhibitors (PPIs). This medicine should be taken one hour before a meal, preferably in the morning. The dose will depend on your underlying condition and how you respond to the medicine. Try to take it regularly at the same time each day as advised by your doctor. You should keep on taking it as prescribed even if your symptoms disappear quickly. You may be able to help improve your symptoms by eating smaller meals more often and avoiding caffeinated drinks like tea and coffee, and spicy or fatty foods. The most common side effects that may be seen with this medicine include nausea, vomiting headache, dizziness, flatulence, diarrhea, and stomach pain. These tend to be mild but talk to your doctor if they bother you or do not go away. The risk of side effects may increase the longer you take this medicine. Long-term use (more than 1 year) may increase your risk for bone fractures, especially with higher doses. Talk to your doctor about ways to prevent bone loss (osteoporosis), like taking calcium and vitamin D supplements. Low blood magnesium levels (hypomagnesemia) have been seen in some people taking this medicine for 3 months or more. This may lead to tiredness, confusion, dizziness, muscle twitches, and an irregular heartbeat. Your doctor may monitor your magnesium levels to prevent this. Dexrabeprazole Sodium is not suitable for some people. Before taking this medicine, you need to tell your doctor if you have severe liver problems, are taking medicines for HIV, have ever had an allergic reaction to similar medicines in the past or suffer from bone loss (osteoporosis). Pregnant or breastfeeding women should also consult their doctor before taking it. Avoid drinking alcohol as it makes your stomach produce excessive acid and can worsen your symptoms. Do not drive or use machinery or tools, if this medicine makes you feel dizzy or sleepy. Dexrabeprazole Sodium is a proton pump inhibitor (PPI). It works by reducing the amount of acid in the stomach which helps in relief of acid related indigestion and heartburn.

• Gastroesophageal reflux disease (Acid reflux) • Peptic ulcer disease

Dexrabeprazole is the chirally pure R (+) enantiomer of racemate Rabeprazole. Dexrabeprazole is a proton pump inhibitor.

Adult Dose: Oral Adult Usual dose: 10 mg once daily in the morning for 4 to 8 weeks depending upon response of patient. Maintenance of healing of GERD may suffice with a lower dose of 5 mg once daily.

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Dexrabeprazole Sodium is to be taken empty stomach.

If you miss a dose of Dexrabeprazole Sodium, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Common: • Nausea • Headache • Flatulence • Diarrhea

[CONSULT YOUR DOCTOR] It is not known whether Dexrabeprazole Sodium alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Dexrabeprazole Sodium should be taken 1 hour before a meal, preferably in the morning. It is a well-tolerated medicine and provides relief for a long time. Avoid eating late at night or before bedtime. Inform your doctor if you get watery diarrhea, fever or stomach pain that does not go away. Inform your doctor if you do not feel better after taking it for 14 days as you may be suffering from some other problem that needs attention. Long-term use of Dexrabeprazole Sodium can cause weak bones and a deficiency of minerals such as magnesium. Take adequate dietary intake of calcium and magnesium or their supplements as prescribed by your doctor. Consult your doctor right away if you develop decreased urination, edema (swelling due to fluid retention), lower back pain, nausea, fatigue, and rash or fever. These could be signs of a kidney problem.

Hypersensitivity to dexrabeprazole

No clinically significant interactions with drugs metabolized by the CYP450 system. An interaction with compounds (e.g. Ketoconazole) which are dependent on gastric pH for absorption may occur due to the magnitude of acid suppression.

[CAUTION] Caution is advised when consuming alcohol with Dexrabeprazole Sodium. Please consult your doctor.

[CONSULT YOUR DOCTOR] Dexrabeprazole Sodium may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

[CONSULT YOUR DOCTOR] Dexrabeprazole Sodium is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

[SAFE IF PRESCRIBED] Dexrabeprazole Sodium is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Dexrabeprazole Sodium may not be needed in these patients. Please consult your doctor. [CAUTION] Dexrabeprazole Sodium should be used with caution in patients with severe liver disease. Dose adjustment of Dexrabeprazole Sodium may be needed. Please consult your doctor.