Dorzolamide 2% eye prep

Dorzolamide 2% eye prep is a medicine used to reduce pressure in the eyes. This pressure can be caused by or lead to an illness called glaucoma. If the pressure in your eye is too high it can damage your sight. Dorzolamide 2% eye prep works by decreasing the amount of fluid inside the eye. Never use Dorzolamide 2% eye prep if the seal is broken before you use it for the first time. Wash your hands before using it and shake the bottle well before each use. Make sure you remove contact lenses if you wear them and wait for at least 15 minutes before putting them back. Do not stop using this medicine without asking your doctor. Otherwise the pressure in your eye will not be controlled and this could damage your sight. The most common side effects of Dorzolamide 2% eye prep are blurred vision and bitter taste in your mouth. Sometimes people experience more general effects such as headache, nausea, tiredness or eye irritation. If your vision is blurred or you have other changes in sight for a time, do not drive until your vision is clear. Do not use this medicine if you have severe kidney problems or are allergic to medicines called sulphonamides. Talk to your doctor before taking it if you have liver problems, dry eyes or cornea problems. Do not use other eye medications unless your doctor tells you to. Dorzolamide 2% eye prep is a carbonic anhydrase inhibitor. It works by decreasing the production of aqueous humour (fluid in the eye), thereby lowering the increased eye pressure.

• Glaucoma

Dorzolamide reversibly inhibits carbonic anhydrase resulting in reduction of hydrogen ion secretion at renal tubule and increased renal excretion of Na, K, bicarbonate, and water, thus decreasing the production of aqueous humor. It also inhibits carbonic anhydrase in CNS to retard abnormal and excessive discharge from CNS neurons.

Adult Dose: Ophthalmic Ocular hypertension; Open-angle glaucoma Adult: Instill 1 drop tid; Child Dose: Ophthalmic Ocular hypertension; Open-angle glaucoma Child: Instill 1 drop tid;

This medicine is for external use only. Take it in the dose and duration as advised by your doctor. Check the label for directions before use. Hold the dropper close to the eye without touching it. Gently squeeze the dropper and place the medicine inside the lower eyelid. Wipe off extra liquid.

If you miss a dose of Dorzolamide 2% eye prep, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Common: • Headache • Nausea • Fatigue • Burning sensation • Bitter taste

[CONSULT YOUR DOCTOR] It is not known whether Dorzolamide 2% eye prep alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Dorzolamide 2% eye prep helps lower high pressure in the eye and reduce the risk of vision loss. For best results, put one drop 2-3 times daily in the affected eye(s). Apply pressure on the corner of the eye (close to the nose) for about 1 minute, immediately after instilling the drop. This minimizes the risk of side effects. Do not touch the tip of the dropper to any surface, or to your eye, to avoid contaminating the eye drops. Remove contact lenses before using Dorzolamide 2% eye prep, and wait at least 15 minutes before re-inserting them. When applying multiple eye medications, wait for at least 5-15 minutes before delivering the next medication in the same eye to avoid dilution of the medicine.

Hypersensitivity Severe reanl impairment (CrCl<30 mL/min)

May increase the serum concentration of alpha-/beta-agonists (indirect-acting). May enhance the adverse/toxic effects of other carbonic anhydrase inhibitors.

No interaction found/established

[CONSULT YOUR DOCTOR] Dorzolamide 2% eye prep may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

[SAFE IF PRESCRIBED] Dorzolamide 2% eye prep is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby. To reduce the amount of Dorzolamide 2% eye prep that reaches the breastmilk, place pressure over the corner of the eye for 1 minute or more, then remove the excess solution with an absorbent tissue.

No interaction found/established No interaction found/established

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