Edaravone

Edaravone is a prescription medicine used in the treatment of amyotrophic lateral sclerosis (a nervous system disease that weakens the muscles and impairs physical functions). It is an antioxidant which slows down nerve damage and prevents further progression of the disease. Edaravone is administered as an injection under the supervision of a healthcare professional and should not be self administered. It is given in cases where oral administration is not possible. Take this medicine in the dose and duration as advised by your doctor and if you have missed a dose, take it as soon as you remember. Some common side effects that may be seen with this medicine include headache, bruising, and walking difficulties. You may also notice some injection site reactions such as pain, redness or swelling. However, these are temporary and usually resolve on their own. Please consult your doctor if these do not subside or bother you. You should inform the doctor if you develop any allergic reactions like itching, swelling of the lips, tongue, or face, after taking the medication as these require immediate medical attention. Edaravone is an antioxidant. It has nootropic (enrichment of nerves) and neuroprotective properties. It works by slowing the nerve damage caused by harmful chemicals (free radicals). This delays the progression of amyotrophic lateral sclerosis (ALS) symptoms by reducing the oxidative stress (an imbalance between free radicals and antioxidants) in the brain.

• Amyotrophic lateral sclerosis (ALS)

As a free radical scavenger, Edaravone lowers N- acetyl aspartate (NAA) and reduce cerebral blood flow into the cerebral infarct areas. The mechanism of Edaravone action reduces cerebral edema and cerebral infarction and lowers lipid-peroxidation induced neuronal death and subsequent oxidative stress of endothelial cells of the brain.

Adult Dose: Intravenous Adult: 30 mg of Edaravone IV two times a day. The course of treatment should be less than 2 weeks. IV infusion of Edaravone should be considered within 24 hours of onset of symptoms.

Your doctor or nurse will give you this medicine. Kindly do not self administer.

Common: • Headache • Bruise • Walking difficulties • Allergic reaction

[CONSULT YOUR DOCTOR] It is not known whether Edaravone alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Edaravone slows decline of physical function and helps relieve symptoms of amyotrophic lateral sclerosis (ALS) such as muscle cramps and fatigue. It is given through a needle into a vein by your healthcare provider. It takes about 60 minutes to receive a full dose of Edaravone. Wear relaxed, loose-fitting clothing and keep yourself hydrated when treated with this medicine. Inform your doctor if you are pregnant or breastfeeding. Inform your doctor immediately if you experience itching, swelling of the lips, tongue, or face, breathing problems or have trouble swallowing after receiving this medicine. Inform your doctor if you have a known allergy to sulfa drugs.

Hypersensitivity

Edaravone should not be used concomitantly with diazepam, phenytoin, cefotetan, piperacillin and cefazolin.

[CONSULT YOUR DOCTOR] It is not known whether it is safe to consume alcohol with Edaravone. Please consult your doctor.

[CONSULT YOUR DOCTOR] Edaravone may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

[CONSULT YOUR DOCTOR] Information regarding the use of Edaravone during breastfeeding is not available. Please consult your doctor.

[CONSULT YOUR DOCTOR] There is limited information available on the use of Edaravone in patients with kidney disease. Please consult your doctor. [CAUTION] Edaravone should be used with caution in patients with severe liver disease. Dose adjustment of Edaravone may be needed. Please consult your doctor. Limited information is available on the use of Edaravone in these patients. No dose adjustment is recommended in patients with mild to moderate liver disease.

Reduced L4-5 and L5 -S1 disc spaces noted with type I endplate degeneration in right lateral corner of L4-5 with patchy h Need to be evaluated clinically. May need intervention like injection or surgery depending on ur symptoms increase weight in one year als take 2 teaspoon honey with 1 glass of milk daily with break fast Tooth pain in left hand side als tab ketorol dt for paingo for x ray of tht tooth I would like a second opinion on the diagnosis of multiple sclerosis. Symptoms- burning of palms, feet and lips for more than 18 months B12, D, ENMG, sugar, normal. General health good. Active lifestyle, regularly exercise. Comprehensive health check done 1 month ago, all normal not sure if u hav emutiple sclerosis clinically; show to aneurologist Hey,this is PATIENT I'm patient of multiple sclerosis. Doctor suggest me to take injection relibeta beta-a. I'm taking this injection since August 2016. Is any other advise to cure. Give me suggestion regarding this. medicine ok ; stronger medicine in selected cases; show to neuroi and discuss Sir / madam I have got pain in my left arm near tennis elbow. it radiatss on pressing. What is reason? Its called lateral epicondylitisIts common in people who are turning or are diabeticAnd have more weightThe main stay of treatment is physiotherapyAnd if no improvement then local injection Multiple sclerosis treatment and medicine. many availabe; show to a neurologist Multiple sclerosis diagnosed with 2 year back what u want to know