Hydralazine

Hydralazine is used in the treatment of heart failure. It is a combination of two medicines that effectively controls symptoms of heart failure. Hydralazine should be taken with food regularly at a fixed time each day. You should take it regularly at evenly spaced intervals as per the schedule prescribed by your doctor. Taking it at the same time every day will help you remember to take it. The dose and duration of treatment will depend on what you are being treated for. Do not stop taking it until you have finished the complete course, even when you feel better. Lifestyle changes like low-fat diet, exercise and not smoking may help this medicine to work better. It is generally safe and suitable for most people but has some potential side effects. The most common side effects of this medicine include nausea, vomiting, diarrhea, and loss of appetite. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. It makes you feel dizzy as of orthostatic hypotension (sudden lowering of blood pressure on standing). Hence, rise slowly while from sitting position or avoid driving. You may be asked for regular monitoring of blood pressure while on the treatment. Before taking this medicine, tell your doctor if you have liver or kidney disease. You must tell your doctor if you are pregnant, planning pregnancy or breastfeeding. You should also let your healthcare team know all other medicines you are taking as they may affect, or be affected by this medicine. Hydralazine is a combination of two medicines: Isosorbide dinitrate and Hydralazine. Isosorbide dinitrate is a nitrate which relaxes the blood vessels and decreases the oxygen demand of the heart. Hydralazine is a potassium channel opener which acts as an antioxidant and lessens tolerance to isosorbide dinitrate, thereby preserving its capacity to relax blood vessels. Together, they improve symptoms of heart failure.

• Heart failure

Hydralazine is a direct-acting vasodilator which acts predominantly on the arterioles. It reduces BP and peripheral resistance but produces fluid retention. Hydralazine tends to improve renal and cerebral blood flow and its effect on diastolic pressure is more marked than on systolic pressure.

Adult Dose: Severe Essential Hypertension 10 mg PO q6hr for 2-4 days; 25 mg q6hr daily for the first week; increase to 50 mg q6hr from second week on; adjust dose to lowest effective levels 20-40 mg IM/IV; repeat as necessary Dosing considerations Change to oral therapy as soon as possible Hypertension (Chronic) Initial: 10 mg PO q6hr for 2-4 days; may increase gradually by 10-25 mg/dose every 2-5 days up to 50 mg PO q6hr (some patients require 300 mg/day) Hypertensive Crisis 20-40 mg IV/IM; repeat PRN Pregnancy-associated 5-10 mg IV/IM initially, THEN 5-10 mg q20-30min PRN, OR 0.5-10 mg/hr IV infusion Congestive Heart Failure Initial dose: 10-25 mg q6-8hr PO Maintenance dose: 225-300 mg/day divided q6-8hr PO Child Dose: Severe Essential Hypertension 1.7-3.5 mg/kg/day IM or IV divided in 4-6 doses. Hypertensive Crisis 3 months - 1 year: 0.1-0.5 mg/kd/dose IV q6-8hr; not to excced 2 mg/kg IV q6hr; titrate dose for blood pressure control >1 year: 0.1-0.2 mg/kg IV/IM q4-6hr PRN initially; may increase to usual dose of 1.7-3.5 mg/kg/day divided q4-6hr; not to exceed 20 mg/dose IM or IV or 2 mg/kg q3-6hr with cumulative dose not to exceed 9 mg/kg Hypertension (Chronic) Initial: 0.75-1 mg/kg/day PO divided q6-12hr Maximum dose in infants (1 year): 7.5 mg/kg/day PO divided q6hr; not to exceed 200 mg/day Increase gradually over 3-4 weeks

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Hydralazine is to be taken with food.

Common: • Nausea • Vomiting • Diarrhea • Loss of appetite • Headache • Flushing (sense of warmth in the face, ears, neck and trunk) • Dizziness • Increased heart rate • Orthostatic hypotension (sudden lowering of blood pressure on standing) • Chest pain • Drug-induced lupus syndrome • Palpitations • Decreased blood pressure • Swelling of hands • Feet swelling

[UNSAFE] Hydralazine may cause side effects which could affect your ability to drive. As Hydralazine may cause headaches or lead to difficulty in concentration and this may affect your ability to drive. Hydralazine is a combination of two medicines that helps improve symptoms of heart failure and keeps your heart healthier. This medicine may temporarily cause headaches, especially when starting treatment. Inform your doctor if it does not go away. Hydralazine may cause dizziness. Do not drive or do anything requiring concentration until you know how it affects you. To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down. It is best to avoid drinking alcohol while taking Hydralazine as it may make the side effects worse. Do not take it in combination with medicines that treat erectile dysfunction (eg. sildenafil, tadalafil, vardenafil) or high blood pressure, as that can cause a major drop in blood pressure. Do not stop taking Hydralazine suddenly without talking to your doctor as it can increase the risk of heart attack and stroke.

Hypersensitivity to hydralazine, Severe tachycardia, dissecting aortic aneurysm, heart failure with high cardiac output, cor pulmonale, myocardial insufficiency due to mechanical obstruction, coronary artery disease, idiopathic SLE. Patients with recent MI.

Hypotensives, diazoxide, NSAIDs, oestrogens, sympathomimetics.

[UNSAFE] Consuming alcohol while taking Hydralazine may cause symptoms such as flushing, increased heart beat, nausea, thirst, chest pain and low blood pressure (Disulfiram reaction).

[CONSULT YOUR DOCTOR] Hydralazine may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

[SAFE IF PRESCRIBED] Hydralazine is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

[CAUTION] Hydralazine should be used with caution in patients with severe kidney disease. Dose adjustment of Hydralazine may be needed. Please consult your doctor. Regular monitoring of blood pressure is recommended for better dose adjustment. [SAFE IF PRESCRIBED] Hydralazine is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Hydralazine may not be needed in these patients. Please consult your doctor.

What for Nefrosave tablet is recommended ??? Nefrosave Tablet Uses Nefrosave Tablet is used for the treatment, control, prevention, & improvement of the following diseases, conditions and symptoms: High Blood Pressure Join 148 Pro Subscribers Hereditary Disorder Affecting The Exocrine Glands Hepatitis Join 48 Pro Subscribers Carbon Tetrachloride Poisoning Join 75 Pro Subscribers Acute Bronchitis Join 74 Pro Subscribers Chronic Bronchitis Paracetamol Poisoning Congestive Heart Failure High Cholesterol Clotting in right leg.after trying tablet wefron2mg . Xerlton15mg is going on.but itching comes on full body. Itching not stopping.what may be reason for itching. Thodi sans bhi fulti he there ke kidney failure can be reason or heart attackconsult cardiologist and nephrologist What is BNP test? Pls explain. What is BNP ASSAY?My result is133.0 explain BNP levels below 100 pg/mL indicate no heart failure. BNP levels of 100-300 pg/mL suggest heart failure is present. BNP levels above 300 pg/mL indicate mild heart failure. BNP levels above 600 pg/mL indicate moderate heart failure.The level of BNP in the blood increases when heart failure symptoms worsen, and decreases when the heart failure condition is stable Myself is high B.P patients .There is some swelling in the face today . what is going on? Kidney damage or heart failure I have heart failure complain when awake in early morning What symptoms do u have any reports done Hypothyroidism 100 mg tablet daily.and premature ovarian failure. OK. I would like suggest you that please consult with your nearest homeopathy doctor. From last three years I am using GLIMESTAR tablet daily each one morning and evening.Do I want to take other tablet or use the same tablet?.On fasting Blood sugar level is 140 after food it is 180 Dose adjustment needed if you are not having any diet failure. So confirm about your diet failure and discuss with your doctor My rbs is 195 , after i am taking glyciphage 500 one tablet two times daily. So which tablet is suitable for me to control my sugar My plasma glucose randomly is 195 after I am taking glyciphage500 one tablet two times daily. So which tablet is now suitable for me to control my sugar problem Needs dose adjustment in the medicine you are taking, if you are not having any diet failure. So confirm about your diet failure and discuss with your doctor.