Lincomycin

Lincomycin is an antibiotic medicine that fights bacteria. It is used to treat bacterial skin infections such as acne, which appears as spots or pimples on your face, chest or back. This medicine works by attacking the germs that cause them. Lincomycin is only meant for external use and should be used as advised by your doctor. You should normally wash and dry the affected area before applying a thin layer of the medicine. It should not be applied to broken or damaged skin. Avoid contact with your eyes, nose or mouth. Rinse it off with water if you accidentally get it in these areas. It may take several weeks for your symptoms to improve, but you should keep using this medicine regularly. Do not stop using it as soon as your acne starts to get better. Ask your doctor when you should stop treatment. Side effects like minor itching, burning, or redness of the skin and oily skin may be seen in some people. These are usually temporary and resolve on their own. Consult your doctor if they bother you or do not go away. It is a safe medicine, but you should inform your doctor if you have any problems with your bowels (intestines), if you have ever had bloody diarrhea caused by taking antibiotics or if you are using any other medicines to treat skin conditions. Consult your doctor about using this medicine if you are pregnant or breastfeeding. Lincomycin is an antibiotic. It works by preventing synthesis of essential proteins required by bacteria to carry out vital functions. Thus, it stops the bacteria from growing, and prevents the infection from spreading.

• Bacterial skin infections

Lincomycin exerts bacteriostatic and bactericidal effects by binding to 50S ribosome subunit. This results in inhibition of protein synthesis, specifically peptide-bond formation in susceptible organisms.

Adult Dose: Intravenous Severe anaerobic infections Adult: IM: 600 mg q12-24hr IV: 600-1000 mg q8-12hr; not to exceed 8 g/day Child Dose: Intravenous Severe anaerobic infections Child: 1 month old IV: 10-20 mg/kg/day divided q8-12hr IM: 10 mg/kg q12-24hr Renal Dose: Renal Impairment, severe: 25-30% of usual dose

This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the gel. Wash your hands after applying, unless hands are the affected area.

If you miss a dose of Lincomycin, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Common: • Application site reactions (burning, irritation, itching and redness)

No interaction found/established You have been prescribed Lincomycin for the treatment of acne. You may have to use it for a long time before your acne starts to improve. Be patient and keep using it every day. Apply it as a thin layer onto clean, dry, unbroken skin affected by acne. It may cause minor burning, stinging, or irritation when applied. Inform your doctor if this does not go away. Avoid contact with your eyes, nose or mouth. Rinse it off with water if you accidentally get the cream in these areas. If you think the area of skin you are treating has become more irritated and infected, you should stop using Lincomycin and consult your doctor.

Hypersensitivity to lincomycin or clindamycin

May potentiate effects of neuromuscular blocking agents (e.g. pancuronium, tubocurarine). Reduced GI absorption w/ kaolin. May antagonise the effect of erythromycin.

No interaction found/established

[CONSULT YOUR DOCTOR] Lincomycin may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

[SAFE IF PRESCRIBED] Lincomycin is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.

No interaction found/established No interaction found/established

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