Generic
Nevirapine
0 brands available in the market
At a glance
Nevirapine — brands, prices, indication, dosage and side effects available in Bangladesh.
Description
Nevirapine belongs to a group of medicines called antiretrovirals. It is used to treat HIV (human immunodeficiency virus), the virus that can cause AIDS (acquired immunodeficiency syndrome). It helps to control HIV infection so your immune system can work better. Nevirapine reduces the chances of getting HIV-related complications and improves your lifespan. It can be taken empty stomach or with food and is prescribed in combination with other HIV medicines. Taking all these medicines regularly at the right times greatly increases their effectiveness and reduces the chances of HIV becoming resistant to them. It is important to keep taking them regularly until your doctor tells you it is safe to stop. Common side effects of this medicine include headache, nausea, vomiting, stomach pain, fatigue, diarrhea, and rash. These are usually not serious but tell your doctor if they bother you or do not go away. Consult your doctor urgently if you experience a skin reaction or liver damage. Before taking it, tell your doctor if you have any skin, liver or kidney problems. While using it, you may need regular blood tests to check your blood cell counts and liver function. Avoid drinking alcohol as it may increase your risk of liver damage. Pregnant or breastfeeding mothers should consult their doctor before using this medicine. Do not have unprotected sex or share personal items like razors or toothbrushes, if you are HIV positive. Talk to your doctor about safe ways like condoms to prevent HIV transmission during sex. Nevirapine prevents the multiplication of HIV virus in human cells, thereby stopping the HIV virus from producing new viruses.
Indications
• HIV infection
Mechanism of action
Nevirapine is a non-nucleoside reverse transcriptase inhibitor that acts against HIV-1. It binds directly to reverse transcriptase and thereby blocks the RNA-dependent and DNA-dependent DNA polymerase activities by disrupting the enzyme's catalytic site.
Dosage
Adult Dose: Oral HIV infection Adult: Combined with other antiretrovirals: 200 mg once daily for the first 14 days; increase to 200 mg bid if rash does not develop. Interrupting the treatment for >7 days necessitate reintroduction at a lower dose for the first 14 days. Child Dose: Oral HIV infection Child: Combined with other antiretrovirals: 2 mth to 8 yr: 4 mg/kg once daily for the first 14 days; increase to 7 mg/kg bid if no rash is present. 8-16 yr: 4 mg/kg once daily for 14 days followed by 4 mg/kg bid. Max: 400 mg daily. Interrupting the treatment for >7 days necessitate reintroduction at a lower dose for the first 14 days. Renal Dose: Renal impairment: Haemodialysis: A further 200-mg dose is recommended after dialysis.
Administration
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Nevirapine may be taken with or without food, but it is better to take it at a fixed time.
Side effects
Common: • Rash • Headache • Agranulocytosis (deficiency of granulocytes in the blood) • Vomiting • Allergic reaction • Nausea • Abdominal pain • Fatigue • Fever • Increased liver enzymes • Diarrhea
Precautions & warnings
[UNSAFE] Nevirapine may cause side effects which could affect your ability to drive. You may experience fatigue while taking Nevirapine and this may affect your ability to drive. You have been prescribed Nevirapine for the treatment of HIV (human immunodeficiency virus). Take it as per dose and duration suggested by your doctor. If you miss a dose for more than 7 days, consult your doctor as dose modification may be required. You might notice skin reactions during the first 2 weeks of treatment. Inform your doctor if you notice a fever, swelling of face, mouth sores, blistering of skin and trouble breathing. Your doctor may check your liver function regularly for a period of 18 weeks. Inform your doctor if you notice yellowing of eyes or skin, dark urine or stomach pain. It makes birth control pills less effective in nature. Ask your doctor about other suitable methods of preventing pregnancy.
Contraindications
Hypersensitivity. Lactation. Severe hepatic impairment.
Drug interactions
Mutually increased levels effects when used with drugs extensively metabolised by CYP3A. Reduced levels/effects of methadone.
Food interactions
[CAUTION] Caution is advised when consuming alcohol with Nevirapine. Please consult your doctor.
Use in pregnancy
[SAFE IF PRESCRIBED] Nevirapine is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Use in lactation
[SAFE IF PRESCRIBED] Nevirapine is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Renal / hepatic impairment
[SAFE IF PRESCRIBED] Nevirapine is safe to use in patients with kidney disease. No dose adjustment of Nevirapine is recommended. However, inform your doctor if you have any underlying kidney disease. [CAUTION] Nevirapine should be used with caution in patients with liver disease. Dose adjustment of Nevirapine may be needed. Please consult your doctor. Use of Nevirapine is not recommended in patients with moderate to severe liver disease. Regular monitoring of liver function tests is advised while you are taking this medicine.
Common questions
i have unprotected sex with my friend. Can I take any drugs now to prevent any STD/HIV infection Hello PATIENT to 1mg. There is some medicine for prophylactic but you need to see physician for prescription and better you check HIV status of both partner hello, one of my frnd suffering with hiv infection from last 2yrs her cd4 is more than 470 and viral load is zero undetectable now she is using art medicines i have doubt that can we have to use art medicine in the whole life or can we stop it once we get viral load zero You still need to be on ART even if the viral load is undetectable I am suffering from HIV 1 infection. Take medicines then and monitor ur cd4 count periodically What are the symptoms of HIV infection Fever, sourthroat, loosemotions, rashes on body, enlarged lymphnodes Plz suggest tablet for throughte infection (oil infection) Visit ent specialist for complete examination as it can be tonsillitis Plz suggest tablet for urine infection Pls show your urine R/m & utine culture reports first. when symptoms of hiv can be seen.what is the test name for digonosefir hiv Hi Kindly consult to your nearest hospital I don't have hiv but what is symptoms Tell me symptoms of hiv List of symptoms is big as many organ system can be involved in HIV. It is beyond the scope of this form