Generic
Roxatidine
0 brands available in the market
At a glance
Roxatidine — brands, prices, indication, dosage and side effects available in Bangladesh.
Description
Roxatidine is an antacid medicine. It reduces the excess amount of acid made by your stomach. It is used to treat and prevent heartburn, indigestion and other symptoms caused by too much acid in the stomach. It is also used to treat and prevent stomach ulcers, reflux disease, and some rarer conditions. Roxatidine is also commonly prescribed to prevent stomach ulcers and heartburn caused due to the use of pain killers. It must be swallowed whole with water before or after a meal. The medicine must be taken in dose and duration advised by the doctor. This medicine should relieve indigestion and heartburn within a few hours. If the symptoms persist or get worse even after 14 days of treatment, you should consult your doctor immediately. Do not take this medicine in severe stomach disease. You can help the medicine work better by eating smaller meals more often and avoiding spicy or oily foods. Most people who take it do not have any side effects, but the most common include fatigue, drowsiness, headache, constipation, diarrhea and muscle pain. If you do get a side effect, it is usually mild and will go away when you stop taking this medicine or as you adjust to it. Consult your doctor if any of these side effects bother you or do not go away. Before taking it, you should tell your doctor if you have any kidney or liver diseases so that your doctor can prescribe a suitable dose for you. Also, tell your doctor if you are taking other medications. This medicine is usually considered safe to take during pregnancy and breastfeeding if it has been prescribed by a doctor. Avoid drinking alcohol as this can increase the amount of acid in your stomach and make your symptoms worse. Roxatidine is a histamine H2 receptor antagonist. It works by reducing the acid produced in the stomach which helps in relief of acid-related indigestion and heartburn.
Indications
• Gastroesophageal reflux disease (Acid reflux) • Peptic ulcer disease
Mechanism of action
Roxatidine is a potent and selective inhibitor of basal and stimulated gastric acid secretion through competitive blockade of H2-receptors. Total pepsin secretion is reduced in a dose-dependent manner. There is an independent mucosal protection action.
Dosage
Adult Dose: Oral Peptic ulcer Adult: 150 mg at bedtime or 75 mg bid daily for 4-6 wk. Maintenance: 75 mg at bedtime. Gastro-oesophageal reflux disease Adult: 75 mg bid or 150 mg at bedtime for 6-8 wk. Gastritis Adult: 75 mg once daily in the evening. Zollinger-Ellison syndrome Adult: 75 mg bid. Premedication before anaesthesia Adult: 75 mg in the evening on the day before surgery and repeated 2 hr before induction of anaesthesia. Alternatively, 150 mg once on the night before surgery. Intravenous Upper gastrointestinal haemorrhage Adult: 75 mg bid via slow inj or infusion. Renal Dose: Renal impairment: CrCl (ml/min) Dosage Recommendation 20-50 75 mg at bedtime. <20 75 mg every 2 days.
Administration
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Roxatidine may be taken with or without food, but it is better to take it at a fixed time.
Missed dose
If you miss a dose of Roxatidine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Side effects
Common: • Fatigue • Drowsiness • Headache • Constipation • Diarrhea • Muscle pain
Precautions & warnings
[CONSULT YOUR DOCTOR] It is not known whether Roxatidine alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Take Roxatidine before going to bed if you are taking this medicine once a day. It is very effective in controlling stomach acid that is released when you are asleep. If you are also taking other medications to treat acidity (e.g., antacid), take them 2 hours before or after taking Roxatidine. Avoid taking soft drinks, citrus fruits like orange and lemon, which can irritate the stomach and increase acid secretion. Inform your doctor if you do not feel better after taking Roxatidine for 2 weeks as you may be suffering from some other problems. Inform your doctor if you have ever been diagnosed with kidney disease as dose of your medicine may need to be adjusted. Do not stop taking the medication without talking to your doctor.
Contraindications
Lactation. Porphyria.
Drug interactions
May affect serum levels of protease inhibitors.
Food interactions
[UNSAFE] It is unsafe to consume alcohol with Roxatidine.
Use in pregnancy
[CONSULT YOUR DOCTOR] Information regarding the use of Roxatidine during pregnancy is not available. Please consult your doctor.
Use in lactation
[CONSULT YOUR DOCTOR] Information regarding the use of Roxatidine during breastfeeding is not available. Please consult your doctor.
Renal / hepatic impairment
[CONSULT YOUR DOCTOR] There is limited information available on the use of Roxatidine in patients with kidney disease. Please consult your doctor. [CONSULT YOUR DOCTOR] There is limited information available on the use of Roxatidine in patients with liver disease. Please consult your doctor.
Common questions
Heartburn Mental disorder Depression Frequent persistent heartburn Gastroesophageal reflux disease Irritable bowel syndrome Indigestion Back flow of acid from stomach Difficulty in swallowing Inflammation of esophagus Excess acid secretion by stomach Intestinal or stomach ulcers You need to be examined in clinic to reach a diagnosis and then appropriate medicine can be prescribed Having problem of acid reflux disease with throat infection and pain in right side of abdomen take avipattikar churan 1 spoon twice before meal, for throat infection do gargles with lyuke warm water and mixing tankan bhasma a littlein it,, My cough is not getting cured since 4-6 months. Tried some doctors, their medicines work for some time and the dry cough starts again. Though it happens occasionally, but i still cough It can be allergic cough or acid reflux disease. Can't give more opinion without seeing acid reflux, gastric, sugar stimulate acid reflux. CBC,ESR,LIPID PROFILE,URINE RE/CS, KFT, LFT, VIT D & B estimation,TAKE RABEKIND DSR once a day empty stomach FOR 3 week Suffering from acid reflux disease due to which pain in throat and right side of lower abdomen Dear sir for the time being you can take Robinia 30, 04 drops in half cup water and Nixocid tab 2 tab thrice daily for a month, but as this case needs supervision, discussion and examination you need to visit a homeopath so that he can discuss your case in detail, get some investigations, do examination and guide you accordingly, Moderate Throat Pain in left side Moderate Ear pain. Acid reflux too often it may be due to acidity also you may have got some ulcer or infection in that region visit ent specialist near you for proper examination Grade one fatty liver with excessive bowel gases seen? Acid peptic disease /colities. Ok tell me the duration of problem Acid Reflux treatment and cause? Cause your food habits and lifestyle. Treatment if at all you want you need to call