Stavudine

Stavudine belongs to a group of medicines called antiretrovirals. It is used to treat HIV (human immunodeficiency virus), the virus that can cause AIDS (acquired immunodeficiency syndrome). It helps to control HIV infection so your immune system can work better. Stavudine is not a cure for HIV or AIDS and only helps to decrease the amount of HIV in your body. This helps to lower your risk of getting HIV-related complications and improves your lifespan. It is prescribed in combination with other HIV medicines. Your doctor will recommend the best medicines for you and will decide the doses that you need. Follow carefully the instructions for all the medicines that you are given. It can be taken with or without food. Taking all these medicines regularly at the right times greatly increases their effectiveness and reduces the chances of HIV becoming resistant to them. It is important not to miss doses and to keep taking them until your doctor tells you it is safe to stop. Common side effects of this medicine include headache, nausea, vomiting, stomach pain, fatigue, diarrhea, and rash. These are usually not serious but tell your doctor if they bother you or do not go away. Rarely, some people may experience a skin reaction or liver damage. Your doctor will closely monitor you for these in the initial period of treatment. Before taking it, tell your doctor if you have any skin problems or liver or kidney disease. While using it, you may need regular blood tests to check your blood counts and liver function. Avoid drinking alcohol as it may increase your risk of liver damage. Pregnant or breastfeeding mothers should consult their doctor before using this medicine. Do not have unprotected sex or share personal items like razors or toothbrushes, if you are HIV positive. Talk to your doctor about safe ways like condoms to prevent HIV transmission during sex. Stavudine is an antiviral medication. It prevents the multiplication of virus in human cells. This stops the virus from producing new viruses and clears up your infection.

• HIV infection

Stavudine, a thymidine analogue, is converted intracellularly to the active metabolite stavudine triphosphate which inhibits HIV reverse transcriptase by competing w/ the natural substrate, thymidine triphosphate. It also inhibits viral DNA synthesis by causing DNA chain termination.

Adult Dose: Oral HIV infection Adult: 60 kg: 40 mg 12 hrly. Child Dose: Oral HIV infection Child: Birth to 13 days 0.5 mg/kg 12 hrly; >14 days 30 kg: Same as adult dose. Renal Dose: CrCl (mL/min) Dosage <26 <60 kg: 15 mg 24 hrly; ?60 kg: 20 mg 24 hrly. 26-50 <60 kg: 15 mg 12 hrly; ?60 kg: 20 mg 12 hrly.

Take this medicine in the dose and duration as advised by your doctor. Do not chew, crush or break it. Stavudine is to be taken empty stomach.

If you miss a dose of Stavudine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Common: • Fatigue • Headache • Nausea • Dizziness

[UNSAFE] Stavudine may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur. In combination with other medicines, it is used for the treatment of HIV infections. Take it with food, as this increases the absorption of the medicine into the body. Stavudine may cause dizziness or sleepiness. Do not drive or do anything requiring concentration until you know how it affects you. You may still develop infections or other illnesses associated with viral infection while taking this medication. You can also pass on HIV or HBV to others. Don't share needles or personal items that can have blood or body fluids on them. During treatment and for at least six months after stopping this medicine, regular blood tests are needed to monitor your liver function, level of hepatitis B virus and blood cells in your blood.

Hypersensitivity to stavudine. Lactation.

Increased risk of pancreatitis, peripheral neuropathy and hepatotoxicity in combination w/ didanosine and hydroxycarbamide. Risk of hepatic decompensation w/ interferon and ribavirin. Risk of peripheral neuropathy w/ isoniazid. Zidovudine may decrease the phosphorylation of stavudine to its active triphosphate form. Doxorubicin and ribavirin may inhibit stavudine activation.

[CAUTION] Caution is advised when consuming alcohol with Stavudine. Please consult your doctor.

[CONSULT YOUR DOCTOR] Stavudine may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

[SAFE IF PRESCRIBED] Stavudine is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

[CAUTION] Stavudine should be used with caution in patients with kidney disease. Dose adjustment of Stavudine may be needed. Please consult your doctor. [SAFE IF PRESCRIBED] Stavudine is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Stavudine may not be needed in these patients. Please consult your doctor. Inform your doctor if you develop any signs and symptoms of jaundice while taking Stavudine. You may need to stop taking this medicine.

i have unprotected sex with my friend. Can I take any drugs now to prevent any STD/HIV infection Hello PATIENT to 1mg. There is some medicine for prophylactic but you need to see physician for prescription and better you check HIV status of both partner hello, one of my frnd suffering with hiv infection from last 2yrs her cd4 is more than 470 and viral load is zero undetectable now she is using art medicines i have doubt that can we have to use art medicine in the whole life or can we stop it once we get viral load zero You still need to be on ART even if the viral load is undetectable I am suffering from HIV 1 infection. Take medicines then and monitor ur cd4 count periodically What are the symptoms of HIV infection Fever, sourthroat, loosemotions, rashes on body, enlarged lymphnodes Its an accidental case I fell down from the tree in childhood stag afterwards I continued feel pain in my chest an also growing like pigeon chest I consultant many doctor but they gave same reason its from birth there is nothing to worrying but me continues suffering Please Share latest X-rays of the affected region What is the Best topical ointmentand systemic capsule for ringworm infection? What is the best topical ointment and capsule for ringworm infection? pictures to be sentneeds to be identified first and then treatedStop all other creams applications. Cap. Itraconazole (Itrasys/ Canditral) 100mg twice daily for 2 weeks. Sertacide Cream for application twice daily for 1 month.Tab. Fexova 180 mg (if required in case of itching) Blood Test- Serum Insulin Fasting & PP. The treatment has to be complete otherwise it will be recur. I have high BP and Iam using 40 mg tablet. Now BP is normal from long time so can I decrease the dose to 20 mg tablet. If it&#x27;s normal on 40mg, continue 40mg I have been suffering from sinus infection from 12 years Take nilsin capsule 2 capsule twice, add shadbindu oil drops in each of your nostril