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Sulphamethoxazole 200 mg +Trimethoprim 40 mg/ml

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Sulphamethoxazole 200 mg +Trimethoprim 40 mg/ml — brands, prices, indication, dosage and side effects available in Bangladesh.

Description

Sulphamethoxazole 200 mg +Trimethoprim 40 mg/ml is a combination medicine that is used to treat various types of bacterial infections such as pneumonia, bronchitis, infections of urinary tract, ear, and abdomen. It prevents the growth of microorganisms to cure the infection. Sulphamethoxazole 200 mg +Trimethoprim 40 mg/ml is a prescription medicine that is advised to be taken as suggested by the doctor. It should be taken with food and it must be taken at a fixed time to ensure better efficacy. Do not consume more than the recommended dose, as an overdose of it may have harmful effects on your body. If you miss a dose, take it as soon as you remember. The treatment must be completed even if you feel better to ensure a complete recovery. Sulphamethoxazole 200 mg +Trimethoprim 40 mg/ml may lead to some side effects such as nausea, vomiting, stomach pain, loss of appetite, headache, etc. To overcome any such side effects, it is advised to eat a healthy balanced diet and drink plenty of fluid. If any of the side effects get aggravated, contact your doctor immediately. If you experience any allergic reaction (rashes, itching, swelling, shortness of breath, etc.), you must consult your doctor immediately. Before taking this medicine, you should tell your doctor if you have any problems with your liver or kidneys. Also, tell your doctor if you are on any medication for any health condition. Pregnant or breastfeeding women should also consult with the doctors before taking it. Avoid drinking alcohol as it can cause excessive dizziness with this medicine. It usually does not impair your ability to drive, but you should not drive if it makes you feel sleepy or dizzy. If you are a known allergic to the medicine, you must refrain from using this medicine and consult your doctor. It is advised to take proper rest during the course of treatment for the medicine to work effectively. Sulphamethoxazole 200 mg +Trimethoprim 40 mg/ml is a combination of two antibiotics: Sulfamethoxazole and Trimethoprim. These antibiotics work by preventing the bacteria from producing folic acid, a nutrient required for bacterial multiplication. Together, they treat your infection effectively.

Indications

• Bacterial infections

Mechanism of action

Co-trimoxazole exhibits the synergistic actions of its components (sulfamethoxazole and trimethoprim) by 10-fold. Sulfamethoxazole inhibits dihydrofolic acid formation from PABA, thus interfering with synthesis and growth of bacterial folic acid. Trimethoprim inhibits enzymes folic acid pathway, preventing the reaction of the dihydrolic acid to tetrahydrofolate. Co-trimoxazole possesses bactericidal effects against E coli, Klebsiella spp, Enterobacter spp, M morganii, P mirabilis, P vulgaris, H influenzae, Strep pneumoniae, Pneumocystis (carinii) jiroveci, Cyclospora spp.

Dosage

Adult Dose: Intravenous Acute exacerbations of chronic bronchitis ; Acute otitis media; Urinary tract infections Adult: 960 mg bid. Severe infections: 2.88 g daily in 2 divided doses. Pneumocystis (carinii) jiroveci pneumonia Adult: 120 mg/kg daily in 2-4 divided doses by infusion over 60-90 min for 14-21 days. Prophylaxis of Pneumocystis(carinii) jiroveci pneumonia Adult: 960 mg once daily for 7 days; 960 mg once daily 3 times wkly on alternate days; or 960 mg bid 3 times wkly on alternate days. Doses are given by infusion over 60-90 min. Hepatic impairment: Severe: Contraindicated. Child Dose: Intravenous Acute exacerbations of chronic bronchitis ; Acute otitis media; Urinary tract infections Child: 18 mg/kg 12 hrly. Severe infections: Up to 27 mg/kg 12 hrly. Max: 1.44 g 12 hrly. Pneumocystis (carinii) jiroveci pneumonia Adult: Each ampoule contains sulfamethoxazole 400 mg and trimethoprim 80 mg in 5 mL: Child: >4 wk 120 mg/kg daily in 2-4 divided doses by infusion over 60-90 min for 14-21 days. Prophylaxis of Pneumocystis(carinii) jiroveci pneumonia Child: >4 wk 15-30 mg/kg bid, by infusion over 60-90 min, 2-3 times wkly given on consecutive or alternate days. Renal Dose: Renal impairment: CrCl (ml/min) Dosage Recommendation <15 Not recommended. 15-30 Half the standard dose.

Administration

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Sulphamethoxazole 200 mg +Trimethoprim 40 mg/ml is to be taken with food.

Side effects

Common: • Nausea • Vomiting • Skin rash • Allergic reaction

Precautions & warnings

[CONSULT YOUR DOCTOR] It is not known whether Sulphamethoxazole 200 mg +Trimethoprim 40 mg/ml alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. You have been prescribed Bactrim DS Tablet for the treatment of many types of bacterial infections. Finish the prescribed course of Bactrim DS Tablet, even if you start to feel better. Stopping it early may make the infection come back and harder to treat. Diarrhea may occur as a side effect but should stop when your course is complete. Inform your doctor if it does not stop or if you find blood in your stools. Stop taking Bactrim DS Tablet and inform your doctor if you develop skin rash/blisters or other unexplained skin reaction while taking Bactrim DS Tablet. In case of long-term use, have regular monthly blood tests to monitor your blood cells as suggested by your doctor.

Contraindications

Known hypersensitivity to trimethoprim or sulfonamides; severe hepatic failure or marked liver parenchymal damage, jaundice; serious haematological disorders and porphyria; severe renal insufficiency where repeated measurements of the plasma concentration cannot be performed; history of drug-induced immune thrombocytopenia w/ use of trimethoprim and/or sulfonamides; megaloblastic anaemia due to folate deficiency. Neonates 4 wk. Treatment of Group A β-haemolytic streptococcia. Pregnancy, esp in the period prior to birth. Concomitant use w/ clozapine. Concomitant use w/ leucovorin for the treatment of P. jiroveci in HIV positive patients.

Drug interactions

May increase risk of hyperkalaemia w/ ACE inhibitors. Increased risk of methaemoglobinaemia w/ prilocaine. May increase risk of ventricular arrhythmias w/ amiodarone. May increase dofetilide-induced QT prolongation. May increase risk of dapsone toxicity. May increase risk of crystalluria w/ methenamine. May increase serum rifampicin levels. Enhanced effects of acenocoumarol and warfarin. Enhanced effect of sulfonylureas. May prolong the half-life of phenytoin. May increase risk of megaloblastic anaemia w/ pyrimethamine given in doses of >25 mg wkly. May increase plasma concentrations of lamivudine, zidovudine and zalcitabine. Increased plasma concentrations w/ procainamide and/or amantadine. May increase risk of haematological toxicity w/ mercaptopurine and azathioprine. May increase digoxin levels. Increased risk of thrombocytopenia w/ diuretics. Potassium aminobenzoate may inhibit the effects of sulfonamides. Concomitant use w/ ciclosporin following renal transplantation may result to reversible deterioration of renal function. Potentially Fatal: Increased risk of fatal agranulocytosis w/ clozapine. Concomitant use w/ leucovorin for the treatment of P. jiroveci in HIV positive patients may result to treatment failure and excess mortality.

Food interactions

[CONSULT YOUR DOCTOR] It is not known whether it is safe to consume alcohol with Sulphamethoxazole 200 mg +Trimethoprim 40 mg/ml. Please consult your doctor.

Use in pregnancy

[CONSULT YOUR DOCTOR] Sulphamethoxazole 200 mg +Trimethoprim 40 mg/ml is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Use in lactation

[SAFE IF PRESCRIBED] Sulphamethoxazole 200 mg +Trimethoprim 40 mg/ml is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby. There may be a possibility of skin rash in the baby.

Renal / hepatic impairment

[CAUTION] Sulphamethoxazole 200 mg +Trimethoprim 40 mg/ml should be used with caution in patients with kidney disease. Dose adjustment of Sulphamethoxazole 200 mg +Trimethoprim 40 mg/ml may be needed. Please consult your doctor. Use of Sulphamethoxazole 200 mg +Trimethoprim 40 mg/ml is not recommended in patients with severe kidney disease. [CAUTION] Sulphamethoxazole 200 mg +Trimethoprim 40 mg/ml should be used with caution in patients with liver disease. Dose adjustment of Sulphamethoxazole 200 mg +Trimethoprim 40 mg/ml may be needed. Please consult your doctor. Use of Sulphamethoxazole 200 mg +Trimethoprim 40 mg/ml is not recommended in patients with the severe liver disease.

Common questions

There is a wound on my back,it&#x27;s 1cm in length and 1mm in depth.I have cleaned this and I want to know which cream I use and any medicine which should I take. And tab bactrim ds 1-0-1 I am using bactrim ds tablets for acne which I&#x27;ll get on my scalp so it is advisable to continue? Consult the doctor who has prescribed taht to you, there is ac ourse of antibiotic whic should be completed. Scar on face due to bacterial infections Pic is not clear, plz visit for proper opinion I have a history of recurring yeast and bacterial vaginosis infections. Tab metrogyl 500 mg twice a day x 5 days and tab fluconazole 150 mg three doses alternate days Local doctor said tounsil to my kid . She is vomiting and loose motion with fever, satrogyl o with bactrim and vomihalt we r giving, but she is not eating anything or very less, what should I do Hello, generally oral intake decreases when the child is ill. Encourage intake of fluids to drink.Also start darolac sachet half sachet orally twice daily for next 5 days. I suffering from bacterial infections in my shaving area or too much acne problem. Fudic cream twice a day My child verry high cough and fever in cold sesion try to much doctor but result is no . It&#x27;s will be countiue cough and fever it&#x27;s good to be only antiboitic Antibiotics are required if bacterial infections. Consult child specialist What are use mega-cv dry syrup Child are not drinking milk Mega CV is an antibiotic used to treat bacterial infections

⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.
Sulphamethoxazole 200 mg +Trimethoprim 40 mg/ml — দাম, ব্যবহার, ডোজ ও পার্শ্বপ্রতিক্রিয়া | oshudhkosh