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Zolmitriptan 5% Nasal prep

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Zolmitriptan 5% Nasal prep — brands, prices, indication, dosage and side effects available in Bangladesh.

Description

Zolmitriptan 5% Nasal prep is used to treat acute migraine attacks. It works by narrowing the blood vessels, thereby relieving migraine headaches and preventing the attack from becoming worse. Zolmitriptan 5% Nasal prep should be used as advised and you must follow proper guidance of the doctor. Carry the spray with you as an attack may occur anytime. Do not skip any doses and finish the full course of treatment even if you feel better. If you have missed a dose, take it as soon as you remember it. Side effects associated with the use of this medicine include dryness in mouth, nausea, taste changes, drowsiness and peripheral neuropathy (tingling and numbness of feet and hands). It may cause dizziness, do not drive or operate machinery until you know how this medicine affects you. Inform your doctor if you are suffering from any heart disease as the use of this medicine is contraindicated in some heart problems. Migraine headaches are thought to result from the dilatation (swelling) of blood vessels in the head. Zolmitriptan 5% Nasal prep is rapidly absorbed into the bloodstream through the inner lining of the nose. Once absorbed, it works by constricting (narrowing) the blood vessels in the head, stops transmission of pain signals to the brain, and blocks the release of chemicals that cause nausea and other migraine symptoms. This relieves the migraine attack.

Indications

• Acute migraine headache

Mechanism of action

Zolmitriptan is a selective agonist for serotonin (5HT1 receptors). It relieves migraine by selective constriction of intracranial blood vessels, neuropeptide release inhibition and decreased transmission in the trigeminal pain pathway.

Dosage

Adult Dose: Nasal Acute migraine attacks Adult: 5 mg (1 spray) into 1 nostril as soon as possible after onset of symptoms, repeated at least 2 hr after the 1st dose if symptoms recur w/in 24 hr. Max: 10 mg/day. Safety of treating >4 headaches in a 30 day period is not established. Hepatic impairment: Avoid use. Child Dose: Migraine Nasal spray 12 yr Initial dose: 2.5 mg intranasally at onset of migraine Individual response varies, may increase dose to 5 mg; do not exceed 5 mg per single dose If migraine has not resolved, may repeat dose after 2 hr if needed; not to exceed 10 mg/24 hr Safety not established in the treatment of an average of >4 migraines/30 days

Administration

Use this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Insert the bottle tip into one nostril and close the other nostril. Direct the spray towards the sides of your nostril, away from the cartilage dividing the two sides of your nose. As you spray, breath gently and keep the head upright. Repeat the same process for the other nostrils.

Side effects

Common: • Dizziness • Dryness in mouth • Nausea • Taste change • Drowsiness • Peripheral neuropathy (tingling and numbness of feet and hand)

Precautions & warnings

No interaction found/established You have been prescribed Zolmitriptan 5% Nasal prep for treatment of migraine headaches. Some tips that may help avoid a migraine attack: It may cause sleepiness. Don't drive or do anything that requires mental focus until you know how it affects you. Notify your doctor if your migraine occurs more often after starting the medication. Notify your doctor if you have stomach pain, headache, bloody diarrhoea or worsening high blood pressure. Inform your doctor if you have a history of heart disease or stroke. This medication does not prevent migraine attacks from happening.

Contraindications

Patients at risk of coronary artery disease (post-menopausal women, men >40 yr, hypertension, hypercholesterolemia, smoking, obesity, DM, family history of coronary artery disease) unless evaluated. Wolff-Parkinson-White syndrome; arrhythmias associated with accessory cardiac conduction pathways; previous cerebrovascular accident; uncontrolled or severe hypertension; ischaemic heart disease, history of MI, coronary vasospasm, transient ischaemic attack. Basilar or hemiplegic migraine.

Drug interactions

Increased risk of serotonin syndrome with SSRI, selective serotonin- and norepinephrine-reuptake inhibitors (SNRI). Increased zolmitriptan concentrations with cimetidine, quinolone antibacterials and drugs that inhibit the cytochrome P450 isoenzyme CYP1A2. Potentially Fatal: Increased risk of fatal serotonin syndrome with sibutramine. Increased risk of serotonin syndrome with MAOI and reversible inhibitors of monoamine oxidase type-A (RIMA); do not use zolmitriptan during and for 2 wk after the use of MAOI and RIMAs Do not use within 24 hr of treatment with another 5-HT1 agonist. Increased risk of additive vasoconstriction with ergot alkaloids; zolmitriptan should not be taken within 24 hr of any ergotamine or ergot-type medication.

Food interactions

No interaction found/established

Use in pregnancy

[CONSULT YOUR DOCTOR] Zolmitriptan 5% Nasal prep may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Use in lactation

[SAFE IF PRESCRIBED] Zolmitriptan 5% Nasal prep is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Renal / hepatic impairment

No interaction found/established No interaction found/established

Common questions

I am facing issue of headache from last 3-4 years.i have consulted allopathy and they have given me sibelum 10 for migrane and asked to take metopar(paracetamol) when ever pain is too much.i am nit taking sibelum now but i am taking metopar when ever required.so i want a homeopathy consultatation if it can be cured by homeopathy or the level of headache can be lowered. Currently i face headache once in a week and i had to take metopar. Kindly suggest. My weight 80 kg And i am taking some neuro medicines ( stalopam 10, amitone 10) I also have cholesterol and taking (atorec 20) Migraine and headache are two different things migraine is primarily headache of one side in symmetrically He has a problem of headache.what is the reason of headache in childMRI nd all reports are normal Migraine, Tension-type headache, Cluster headache and Chronic daily headache are few examples of reason I have suffering for headache like migraine http://www.1mgayush.com/NervousSystem/products/CEPHAGRAINE/Standardhttp://www.1mgayush.com/products/Cephagraine-Nasal-Drops/Standarduse these medicine at least 3 months & avoid spicy and oily food Naxdom 500 uses benifit please Used for acute headache My sister, she gets head ache when she completes her bath or when exposed to cold. When consultanted with an opthalmologist he said there isn't any eye power. Later consulting an other general physician he told that it is due to sinus and migraine and recommend to use half tablet of sinarest and then it decreases. So please advice me What's her problem? It could be migraine or tension type headache Suffering from headache which starts from both sides tension like and then progresses to only left side, vomiting intentionally gives relief Using zolmist nasal spray (zolmitriptan) gives immediate relief Looks like migraine Still better 2 get mri brain done for suretyU cn drop msg at 9XXXXXX to fix appointment for further adviceIm available in Gurgaon suffering from nasal congestion tell me the perfect nasal spray it may be due to allergy or infection visit ent specialist near you for proper examination Have acute migraine since last 15 years. The frequency of headache is once a week. The headache occurs on left and right side alternatively. Take nilsin capsule twice,pAthyadi kwath 20 ml twice

⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.
Zolmitriptan 5% Nasal prep — দাম, ব্যবহার, ডোজ ও পার্শ্বপ্রতিক্রিয়া | oshudhkosh