Generic
Albumin Human 5%
At a glance
Albumin Human 5% — brands, prices, indication, dosage and side effects available in Bangladesh.
Description
Albumin Human 5% is used to treat blood volume loss. It works by replacing the body fluids lost due to excessive trauma, bleeding, surgery, or kidney dialysis. Thus, it is helpful in treating low blood albumin levels. Albumin Human 5% must be administered under the supervision of a healthcare professional. You should not take it if you have any known allergy from this injection. Before taking it, inform the doctor you are suffering from any severe heart disease. Your doctor may check your blood pressure and ask you to get regular blood tests done while you are using this injection. The most common side effects include flushing (sense of warmth in the face, ears, neck, and trunk), nausea and fever. Inform your doctor if you are pregnant or breastfeeding or suffering from kidney diseases as a dose adjustment may be required. This injection is safe to use in patients suffering from liver diseases. Albumin Human 5% contains human albumin, a natural protein in blood. It works by replacing the blood or body fluids lost due to excessive bleeding, surgery, or kidney dialysis.
Indications
• Nephrotic syndrome
Mechanism of action
Human albumin increases intravascular oncotic pressure and causes movement of fluids from interstitial into intravascular space. Human albumin solutions are available in various concentrations. Solutions containing 5% human albumin are usually used in hypovolemic patients, whereas more concentrated 25% solutions are recommended in patients in whom fluid and sodium intake must be minimised e.g. patients with hypoproteinaemia or cerebral oedema or in paediatric patients.
Dosage
Adult Dose: Adult: Initially, 25 g of albumin, adjusted according to patient's response. Usual rates of infusion: Up to 5 ml/minute (5% solution). Intravenous Hypoproteinaemia Adult: Up to 2 g/kg daily. Usual rates of infusion: Up to 5 ml/minute (5% solution). Special Populations: Volume admin and rate of infusion must always be individualised according to situation and response. Usual rates of infusion are up to 5 ml/min (5% soln). Child Dose: Child: Up to 1 g/kg, adjusted according to patient's response. Usual rates of infusion: Up to 5 ml/minute (5% solution). Intravenous Neonatal hyperbilirubinaemia Child: 1 g/kg of albumin before exchange transfusion. Usual rates of infusion: Up to 5 ml/minute (5% solution). Special Populations: Volume admin and rate of infusion must always be individualised according to situation and response. Usual rates of infusion are up to 5 ml/min (5% soln).
Administration
Your doctor or nurse will give you this medicine. Kindly do not self-administer.
Missed dose
If you miss a dose of Albumin Human 5%, please consult your doctor.
Side effects
Common: • Vomiting • Flushing (sense of warmth in the face, ears, neck and trunk) • Fever • Nausea • Chills • Hives • Slow heart rate
Precautions & warnings
[SAFE] Albumin Human 5% does not usually affect your ability to drive. It is given as an injection into veins under the supervision of a medical professional. Inform your doctor immediately if you experience a skin rash, itching, breathing difficulties, swelling of face and changes in heartbeat while using this medicine. Inform your doctor if you have history of severe anemia (lack of red blood cells), or severe heart failure.
Contraindications
Cardiac failure, severe anaemia, history of hypersensitivity, parenteral nutrition.
Drug interactions
Albumin solution should not be mixed by protein hydrolysates or alcoholic solutions. Risk of atypical reactions to ACE inhibitors in patients undergoing therapeutic plasma exchange with albumin human replacement.
Food interactions
[CONSULT YOUR DOCTOR] It is not known whether it is safe to consume alcohol with Albumin Human 5%. Please consult your doctor.
Use in pregnancy
[CONSULT YOUR DOCTOR] Albumin Human 5% may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Use in lactation
[CONSULT YOUR DOCTOR] Information regarding the use of Albumin Human 5% during breastfeeding is not available. Please consult your doctor.
Renal / hepatic impairment
[CAUTION] Albumin Human 5% should be used with caution in patients with kidney disease. Dose adjustment of Albumin Human 5% may be needed. Please consult your doctor. [SAFE IF PRESCRIBED] Albumin Human 5% is safe to use in patients with liver disease. No dose adjustment of Albumin Human 5% is recommended.