Ampicillin + Sulbactam

Ampicillin + Sulbactam is a combination of two antibiotics. It is prescribed to treat various types of bacterial infections. It fights against the infection by killing the microorganisms. Ampicillin + Sulbactam is best taken in empty stomach. Take it preferably half to one hour before food. You should take it in the dose and duration as advised by your doctor. The dose will depend on the condition you are being treated for, but you should always complete a full course of the medicine even if you feel better. If you stop taking it early, some bacteria may survive and the infection may come back. Some common side effects of this medicine include nausea, vomiting, diarrhea, and rash. You should contact your doctor if these side effects do not resolve with time and persist for a longer duration. Before using it, you should tell your doctor if you are allergic to any antibiotics or have any kidney or liver problems. Your doctor may change the dose or prescribe a different medicine. This medicine is generally regarded as safe to use during pregnancy if used under a doctor's supervision. However, you should consult with your doctor if you are breastfeeding. Ampicillin + Sulbactam is a combination of two medicines: Ampicillin and Sulbactam. Ampicillin is an antibiotic. It works by preventing the formation of the bacterial protective covering which is essential for the survival of bacteria. Sulbactam is a beta-lactamase inhibitor which reduces resistance and enhances the activity of Ampicillin against bacteria.

• Bacterial infections

Ampicillin binds to 1 or more of the penicillin-binding proteins (PBPs), thus inhibiting the final transpeptidation step of peptidoglycan synthesis in bacterial cell walls. Sulbactam inhibits the activity of beta-lactamases and extends the spectrum of ampicillin to include beta-lactamase producing organisms.

Adult Dose: Parenteral Gynaecological infections; Intra-abdominal infections; Skin and skin structure infections Adult: Each vial contains 1.5 g (ampicillin 1 g and sulbactam 0.5 g) or 3 g (ampicillin 2 g and sulbactam 1 g): 1.5-3 g 6 hrly by deep IM or slow IV inj over 10-15 min or infusion over 15-30 min. Max: 12 g (8 g ampicillin and 4 g sulbactam) daily. Orbital Cellulitis 3 g (2 g ampicillin + 1 g sulbactam) IV q6hr Pelvic Inflammatory Disease 3 g (2 g ampicillin + 1 g sulbactam) IV q6hr Pneumonia Aspiration or community acquired: 1.5 g (1 g ampicillin + 0.5 g sulbactam) to 3 g (2 g ampicillin + 1 g sulbactam) IV q6hr for 5 or more days Hospital acquired: 3 g IV q6hr for 5 or more days Urinary Tract Infections Pyelonephritis: 3 g (2 g ampicillin + 1 g sulbactam) IV q6hr for 14 days Child Dose: Parenteral Gynaecological infections; Intra-abdominal infections; Skin and skin structure infections Child: >1 yr 300 mg/kg daily (ampicillin 200 mg and sulbactam 100 mg) in divided doses 6 hrly by IV infusion. Renal Dose: Renal impairment: Haemodialysis patient: 1.5-3 g once 24 hrly immediately after dialysis. CrCl (ml/min) Dosage Recommendation 5-14 1.5-3 g 24 hrly. 15-29 1.5-3 g 12 hrly.

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Ampicillin + Sulbactam is to be taken empty stomach.

Common: • Nausea • Vomiting • Diarrhea • Rash • Allergic reaction

[CONSULT YOUR DOCTOR] It is not known whether Ampicillin + Sulbactam alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. You have been prescribed this combination medicine to treat bacterial infections even if they have developed resistance. Finish the prescribed course, even if you start to feel better. Stopping it early may make the infection come back and harder to treat. Diarrhea may occur as a side effect. Taking probiotics along with Ampicillin + Sulbactam may help. Talk to your doctor if you notice bloody stools or develop abdominal cramps. Stop taking Ampicillin + Sulbactam and inform your doctor immediately if you develop an itchy rash, swelling of the face, throat or tongue or breathing difficulties while taking it. Do not use leftover medicine for treating any infection in the future. Always consult your doctor before taking any antibiotic.

Hypersensitivity to ampicillin, sulbactam or other β-lactam antibacterials (e.g. penicillins, cephalosporins). History of cholestatic jaundice/hepatic dysfunction associated w/ ampicillin and sulbactam.

Increased and prolonged serum levels w/ probenecid. Increased incidence of rashes w/ allopurinol. May reduce effectiveness of oestrogen-containing OC. May increase risk of methotrexate toxicity. Bacteriostatic drugs (e.g. chloramphenicol) may interfere w/ the bactericidal effect of ampicillin. Additive effect w/ anticoagulants.

[SAFE] Consuming alcohol with Ampicillin + Sulbactam does not cause any harmful side effects.

[SAFE IF PRESCRIBED] Ampicillin + Sulbactam is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

[CAUTION] Ampicillin + Sulbactam should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.

[CAUTION] Ampicillin + Sulbactam should be used with caution in patients with kidney disease. Dose adjustment of Ampicillin + Sulbactam may be needed. Please consult your doctor. [CONSULT YOUR DOCTOR] There is limited information available on the use of Ampicillin + Sulbactam in patients with liver disease. Please consult your doctor.

Scar on face due to bacterial infections Pic is not clear, plz visit for proper opinion I have a history of recurring yeast and bacterial vaginosis infections. Tab metrogyl 500 mg twice a day x 5 days and tab fluconazole 150 mg three doses alternate days I suffering from bacterial infections in my shaving area or too much acne problem. Fudic cream twice a day My child verry high cough and fever in cold sesion try to much doctor but result is no . It's will be countiue cough and fever it's good to be only antiboitic Antibiotics are required if bacterial infections. Consult child specialist What are use mega-cv dry syrup Child are not drinking milk Mega CV is an antibiotic used to treat bacterial infections Sir which medication can we use to fast healing the wound such as minor cut,bacterial infections just apply Neomycin cream locally I get infections around my private parts and also near my toes It's basically fungus or bacterial infection Dear Mr PATIENT need to check your lesions before prescribing any medications, post a high quality image of the lesion with a good resolution.