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Lamivudine + Stavudine + Nevirapine

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At a glance

Lamivudine + Stavudine + Nevirapine — brands, prices, indication, dosage and side effects available in Bangladesh.

Description

Lamivudine + Stavudine + Nevirapine is a combination of antiretrovirals medicines. It is prescribed to treat HIV (human immunodeficiency virus) infection. It boosts up the immunity to fight against HIV to manage or treat AIDS (acquired immunodeficiency syndrome). Lamivudine + Stavudine + Nevirapine restricts the growth of HIV in the body and reduces the risk of getting HIV-related complications to improve the lifespan of an individual. The medicine should be taken in an empty stomach for better efficacy. Taking these medicines regularly at the same time increases their effectiveness. A dose of this medicine should not be missed as it can affect your recovery. It is important to complete the full course of the treatment until your doctor advises you to stop it. Common side effects of this medicine include headache, tiredness, trouble sleeping, nausea, diarrhea, dryness in the mouth, fever, and rash. These side effects are generally temporary, but if they persist or become serious inform your doctor. This medicine can also make you feel dizzy or drowsy, so it is advised to avoid driving. In addition to that, avoid alcohol consumption as it may increase the intensity of the side effects. Before starting with the treatment, you should consult your doctor if you are pregnant or breastfeeding, or have any health condition. Your doctor may suggest regular blood tests to check your blood counts and other bodily functions. If you are HIV positive, you should not breastfeed or share personal belongings like razors or toothbrushes. Consult your doctor to know about safe sex methods in order to prevent transmission of HIV during intercourse. Lamivudine + Stavudine + Nevirapine is a combination of three antiviral medicines: Lamivudine, Stavudine and Nevirapine. They work by preventing HIV (virus) from multiplying, thereby reducing the amount of virus in your body. They also increase the CD4 cell (white blood cells that protect against infection) count in your blood.

Indications

• HIV infection

Mechanism of action

Lamivudine, a synthetic nucleoside analogue, is phosphorylated into the body to the active 5'-triphosphate metabolite. It inhibits RNA- and DNA-dependent polymerase activities of reverse transcriptase via DNA chain termination. Stavudine is converted intracellularly to the active metabolite stavudine 5'-triphosphate which is then incorporated into the viral DNA by reverse transcriptase resulting in premature ending of the DNA chain elongation. Nevirapine is a non-nucleoside reverse transcriptase inhibitor that acts against HIV-1. It binds directly to reverse transcriptase and thereby blocks the RNA-dependent and DNA-dependent DNA polymerase activities by disrupting the enzyme's catalytic site.

Dosage

Adult Dose: Oral HIV infection Adult <60kg: 1 tab twice daily

Administration

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Lamivudine + Stavudine + Nevirapine is to be taken empty stomach.

Side effects

Common: • Headache • Tiredness • Insomnia (difficulty in sleeping) • Nausea • Diarrhea • Dryness in mouth • Fever • Rash • Peripheral neuropathy (tingling and numbness of feet and hand)

Precautions & warnings

[UNSAFE] Lamivudine + Stavudine + Nevirapine may cause side effects which could affect your ability to drive. You may experience fatigue while taking Lamivudine + Stavudine + Nevirapine and this may affect your ability to drive. Stavex LN Tablet is a combination of three medicines which slows down or stops the progression of HIV infections. Take it on an empty stomach, preferably at bedtime, to reduce side effects. Skipping doses increases the risk of treatment failure. Make sure that you take all your doses at the correct time. Stavex LN Tablet may cause dizziness or sleepiness. Don't drive or do anything requiring concentration until you know how it affects you. Stavex LN Tablet can cause birth defects. Use effective contraception while taking Stavex LN Tablet and 12 weeks after stopping it. It may cause weakening of your bones. Exercise regularly and take calcium and vitamin D supplements as suggested by your doctor. Your doctor may monitor your kidney and liver functions regularly. Inform your doctor if you develop symptoms such as abdominal pain, loss of appetite, darkened urine or yellowing of the eyes or skin. Do not stop taking Stavex LN Tablet without your doctor's advice.

Contraindications

Hypersensitivity. Lactation. Severe hepatic impairment.

Drug interactions

Antiviral effect inhibited by zidovudine, doxorubicin and ribavirin. Avoid concurrent admin with drugs that cause pancreatitis (e.g. IV pentamidine) or peripheral neuropathy (e.g. metronidazole, isoniazid and vincristine). Increased risk of adverse effects such as hepatoxicity, peripheral neuropathy and pancreatitis if used with hydroxycarbamide and didanosine. May antagonise the antiviral action of zalcitabine. May enhance the adverse effect of emtricitabine.

Food interactions

[CAUTION] Caution is advised when consuming alcohol with Lamivudine + Stavudine + Nevirapine. Please consult your doctor.

Use in pregnancy

[CONSULT YOUR DOCTOR] Lamivudine + Stavudine + Nevirapine may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Use in lactation

[SAFE IF PRESCRIBED] Lamivudine + Stavudine + Nevirapine is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Renal / hepatic impairment

[CAUTION] Lamivudine + Stavudine + Nevirapine should be used with caution in patients with kidney disease. Dose adjustment of Lamivudine + Stavudine + Nevirapine may be needed. Please consult your doctor. [SAFE IF PRESCRIBED] Lamivudine + Stavudine + Nevirapine is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Lamivudine + Stavudine + Nevirapine may not be needed in these patients. Please consult your doctor. Inform your doctor if you develop any signs and symptoms of jaundice while taking Lamivudine + Stavudine + Nevirapine. You may need to stop taking this medicine.

Common questions

I am having fasting sugar 188 PP 358 Doctor suggest GLYCOMET gp1 before food. Earlier I had Amaryl 2 YoUr pp is v high you continue amryl or Diab aid ln homoeo 20 drops with 40mlwatet before dinner What are the side effects of Eritel LN HS 40 prescribed by not very much may have electrolytes done Dear sir my mother discharge hospital and live ln home pls advice the report Consult physician n nephrologist Iam diabetic ,hypertensive . Iam on myrtle mv2, tenelyglyptide and LN block. Can I use Viagra?Pl advise me Yes. Do an ecg and show it to ur physician or me then start viagra Many times urination at night and pain in left side of back .I am using Telma LN 40 tablets Get ultrasound kub with PVR , uroflowmetry n urine routine examination n culture Due eating of gutkha my teeth were turned into yellowish colour suggest to get it I ln white state get the ultrasonic scaling done by dentist Slightly enlarged prostate. Dribbling of urine and unable to control when feels to go to urinate. He is on blood pressure medication, taking Ln trio and Ln beta daily. Used to take prostate medicines a few years ago when prostate weight was 53g, and then it got reduced to 30g so medication was stopped. Get ultrasound kub with PVR n uroflowmetry I have problem with premature ejaculation. Which medicine I can use.i am using LN BETA 2.5 daily 1 tablet.pls suggest me the right medicine Hello S K PATIENT to 1 mg. PE is common in your age group and since you taking antihypertensive medicine I would like to suggest you for life style modification first.dont take so much tension which is further deteriorate your health. Life style modification with behavioural changes may help you more. There are some technique and take help from your partner. In the ?stop-start? programme, the partner stimulates the penis until the patient feels the urge to ejaculate. At this point, he instructs his partner to stop, waits for the sensation to pass and then stimulation is resumed. Another the ?squeeze? technique is similar but the partner applies manual pressure to the glans just before ejaculation until the patient loses his urge. Apply some cream like Climax spray / EMLA cream which will further help. Along with this do exercise, stop smoking tobacco alcohol n gutkha, eat fruits and take antioxidant multivitamins and vitamin C. Try this for couple of weeks and if not improved i will advice you some medicines.

⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.
Lamivudine + Stavudine + Nevirapine — দাম, ব্যবহার, ডোজ ও পার্শ্বপ্রতিক্রিয়া | oshudhkosh