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Omeprazole + Domperidone

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At a glance

Omeprazole + Domperidone — brands, prices, indication, dosage and side effects available in Bangladesh.

Description

Omeprazole + Domperidone is a prescription medicine used to treat gastroesophageal reflux disease (Acid reflux) and peptic ulcer disease by relieving the symptoms such as heartburn, stomach pain, or irritation. It also neutralizes the acid in the stomach and promotes easy passage of gas to reduce stomach discomfort. Omeprazole + Domperidone is taken without food in a dose and duration as advised by the doctor. The dose you are given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. Let your healthcare team know about all other medications you are taking as some may affect, or be affected by this medicine. Most common side effects are diarrhea, stomach pain, dryness in mouth, headache, and flatulence. Most of these are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any side effects. It may also cause dizziness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Avoid drinking alcohol while taking this medicine as it can worsen your dizziness. Lifestyle modifications like having cold milk and avoiding hot tea, coffee, spicy food or chocolate can help you to get better results. Before taking this medicine, you should tell your doctor if you are pregnant, planning pregnancy or breastfeeding. You should also tell your doctor if you have liver diseases so that your doctor can prescribe a suitable dose for you. Omeprazole + Domperidone is a combination of two medicines: Domperidone and Omeprazole. Domperidone is a prokinetic which works on the upper digestive tract to increase the movement of the stomach and intestines, allowing the food to move more easily through the stomach. Omeprazole is a proton pump inhibitor (PPI) which works by reducing the amount of acid in the stomach which helps in the relief of acid-related indigestion and heartburn.

Indications

• Gastroesophageal reflux disease (Acid reflux) • Peptic ulcer disease

Mechanism of action

Domperidone is a peripheral dopamine D2-receptor antagonist, which regulates the motility of gastric and small intestinal smooth muscle. It increases the duration of antral and duodenal contractions and also LES resting pressure, thus stimulating gastric emptying and is also effective in relief of symptoms of reflux esophagitis. Antiemetic activity is due to the blockade of dopamine receptors in the chemoreceptor trigger zone. Omeprazole inhibits the secretion of gastric acid by irreversibly blocking the enzyme system of H+/K+ ATPase of the gastric parietal cell. It is activated at an acidic pH to a sulphenamide derivative that binds irreversibly to H+/K+ ATPase, an enzyme system found at the secretory surface of parietal cells. It thereby inhibits the final transport of hydrogen ions (via exchange with K ions) into the gastric lumen.

Dosage

Adult Dose: Oral Dyspepsia, Gastro-oesophageal reflux disease Adult: 1 cap bid or as directed by the physician.

Administration

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Omeprazole + Domperidone is to be taken empty stomach.

Side effects

Common: • Diarrhea • Stomach pain • Dryness in mouth • Headache • Flatulence

Precautions & warnings

[UNSAFE] Omeprazole + Domperidone may cause side effects which could affect your ability to drive. Omeprazole + Domperidone may cause dizziness and visual disturbances. This may affect your driving ability. You have been prescribed Aciloc RD 20 Tablet for the treatment of acidity and heartburn. Take it one hour before the meal, preferably in the morning. It is a well-tolerated medicine and provides relief for a long time. Inform your doctor if you get watery diarrhea, fever or stomach pain that does not go away. Inform your doctor if you do not feel better after taking it for 14 days as you may be suffering from some other problem that needs attention. Long-term use can cause weak bones and deficiency of minerals such as magnesium. Take adequate dietary intake of calcium and magnesium or their supplements as prescribed by your doctor.

Contraindications

Pregnancy. Domperidone is contraindicated in conditions associated with rise in prolactin level. Omeprazole is contraindicated in hypersensitive patients.

Drug interactions

Anticholinergics may antagonize beneficial effects of domperidone in reflux oesophagitis and dyspepsia. Decreased bioavailability of domperidone after prior admin of cimetidine or Na bicarbonate. Delayed elimination of diazepam, phenytoin and warfarin with omeprazole.

Food interactions

[CAUTION] Caution is advised when consuming alcohol with Omeprazole + Domperidone. Please consult your doctor.

Use in pregnancy

[CONSULT YOUR DOCTOR] Omeprazole + Domperidone may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Use in lactation

[SAFE IF PRESCRIBED] Omeprazole + Domperidone is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Renal / hepatic impairment

[CAUTION] Omeprazole + Domperidone should be used with caution in patients with kidney disease. Dose adjustment of Omeprazole + Domperidone may be needed. Please consult your doctor. [CAUTION] Omeprazole + Domperidone should be used with caution in patients with liver disease. Dose adjustment of Omeprazole + Domperidone may be needed. Please consult your doctor. Use of Omeprazole + Domperidone is not recommended in patients with moderate and severe liver disease.

Common questions

Aciloc rd with vertin 16 interaction Pls let me know can i take vertin16 with aciloc rd? Pls reply. Its a request Yes you can take Feeling acid reflux for fhe last 4 days.took aciloc and zintac but it comes back Take a cap pentop i. T. Once a day empty stomach Why I am having pain in my calph, both legs, if I run or walk and exceed my daily limit , it will cause to trigger pain Take tablets Tab. K-2 twice a day Tab. Evion 600 twice a day Tab. Aciloc rd once a day Heartburn Mental disorder Depression Frequent persistent heartburn Gastroesophageal reflux disease Irritable bowel syndrome Indigestion Back flow of acid from stomach Difficulty in swallowing Inflammation of esophagus Excess acid secretion by stomach Intestinal or stomach ulcers You need to be examined in clinic to reach a diagnosis and then appropriate medicine can be prescribed Having problem of acid reflux disease with throat infection and pain in right side of abdomen take avipattikar churan 1 spoon twice before meal, for throat infection do gargles with lyuke warm water and mixing tankan bhasma a littlein it,, My cough is not getting cured since 4-6 months. Tried some doctors, their medicines work for some time and the dry cough starts again. Though it happens occasionally, but i still cough It can be allergic cough or acid reflux disease. Can't give more opinion without seeing acid reflux, gastric, sugar stimulate acid reflux. CBC,ESR,LIPID PROFILE,URINE RE/CS, KFT, LFT, VIT D & B estimation,TAKE RABEKIND DSR once a day empty stomach FOR 3 week Suffering from acid reflux disease due to which pain in throat and right side of lower abdomen Dear sir for the time being you can take Robinia 30, 04 drops in half cup water and Nixocid tab 2 tab thrice daily for a month, but as this case needs supervision, discussion and examination you need to visit a homeopath so that he can discuss your case in detail, get some investigations, do examination and guide you accordingly,

⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.
Omeprazole + Domperidone — দাম, ব্যবহার, ডোজ ও পার্শ্বপ্রতিক্রিয়া | oshudhkosh