Telbivudine

Telbivudine is used in the treatment of HIV infection and chronic hepatitis B virus (HBV) infection. It prevents the multiplication of virus in human cells. This stops the virus from producing new viruses and clears up your infection. Telbivudine is prescribed in combination with other HIV medicines. Your doctor will recommend the best medicines for you and will decide the doses that you need. Follow carefully the instructions for all the medicines that you are given. It can be taken with or without food. Taking all these medicines regularly at the right times greatly increases their effectiveness and reduces the chances of HIV becoming resistant to them. It is important not to miss doses and to keep taking them until your doctor tells you it is safe to stop. Common side effects of this medicine include nausea, stomach pain, weakness and headache. These are usually not serious but tell your doctor if they bother you or do not go away. Rarely, some people may experience a skin reaction or liver damage. Your doctor will closely monitor you for these in the initial period of treatment. Before taking it, tell your doctor if you have any skin problems or liver or kidney disease. While using it, you may need regular blood tests to check your blood counts and liver function. Avoid drinking alcohol as it may increase your risk of liver damage. Pregnant or breastfeeding mothers should consult their doctor before using this medicine. Do not have unprotected sex or share personal items like razors or toothbrushes, if you are HIV positive. Talk to your doctor about safe ways like condoms to prevent HIV transmission during sex. Telbivudine is an antiviral medication. It prevents the multiplication of virus in human cells. This stops the virus from producing new viruses and clears up your infection.

• HIV infection • Chronic hepatitis B virus (HBV) infection

Telbivudine is a synthetic thymidine nucleoside analogue. It undergoes intracellular phosphorylation to form its active metabolite, telbivudine triphosphate. Telbivudine triphosphate inhibits hepatitis B viral DNA polymerase; enzyme inhibition blocks reverse transcriptase thus reducing viral DNA replication. It is used in the treatment of chronic hepatitis B infection.

Adult Dose: Oral Chronic hepatitis B Adult: 600 mg once daily. Child Dose: Safety and efficacy not established Child: >16 yr: 600 mg once daily. Renal Dose: Renal impairment: ESRD: 600 mg 96 hrly, after dialysis session. CrCl (ml/min) Dosage Recommendation <30 (not requiring dialysis) 600 mg 72 hrly. 30-49 600 mg 48 hrly.

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Telbivudine may be taken with or without food, but it is better to take it at a fixed time.

If you miss a dose of Telbivudine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Common: • Fatigue • Headache • Nausea • Decreased appetite • Indigestion • Fever • Feeling of discomfort • Dizziness • Muscle pain • Joint pain • Abdominal distension • Insomnia (difficulty in sleeping) • Rash • Back pain • Liver damage

[UNSAFE] Telbivudine may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur. You have been prescribed Telbivudine for the treatment of chronic hepatitis B virus (HBV) infection. In combination with other medicines, it is used for the treatment of HIV infections. Take it with food, as this increases the absorption of the medicine into the body. Telbivudine may cause dizziness or sleepiness. Do not drive or do anything requiring concentration until you know how it affects you. You may still develop infections or other illnesses associated with viral infection while taking this medication. You can also pass on HIV or HBV to others. Don't share needles or personal items that can have blood or body fluids on them. During treatment and for at least six months after stopping this medicine, regular blood tests are needed to monitor your liver function, level of hepatitis B virus and blood cells in your blood.

Hypersensitivity. Lactation. Concurrent use w/ peginterferon alfa-2a.

Increased risk of peripheral neuropathy when used with peginterferon alfa-2a.

[UNSAFE] It is unsafe to consume alcohol with Telbivudine.

[SAFE IF PRESCRIBED] Telbivudine is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

[CONSULT YOUR DOCTOR] Telbivudine is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

[CAUTION] Telbivudine should be used with caution in patients with kidney disease. Dose adjustment of Telbivudine may be needed. Please consult your doctor. Regular monitoring of kidney function tests may be advised before you start taking this medicine and while you are taking this medicine. [SAFE IF PRESCRIBED] Telbivudine is safe to use in patients with liver disease. No dose adjustment of Telbivudine is recommended.

I have HBV related chronic liver problem .Local urologist suggest me to take rapilif d 8 for urine block problem?Can i take that medicine with entavir for hepatitis b virus and cronic liver disease? Yes u can take it Suffering from Hepatitis B virus from last one week. Please suggest me. Pls consult a gastroenterologist How to treatment of HEPATITIS C VIRUS https://www.1mg.com/otc/himalaya-liv.-52-ds-tablet-otc135545One ?one tablet morning & evening after taking food , use at least 1-2 monthsUse this medicine along with your treatment What should be next course of action for me. Pls guide. I am about to be married and really scared. Dear PATIENT from 1mg. The reports shows positive Hepatitis B surface antigen which can be due to Hepatitis B infection. I suggest you should consult a Hepatologist/ Gatroenetrologist/ Physician for this. I M HBSAG ( HEPATITIS B POSITIVE) SO SIR any treatment treat my infection https://goo.gl/forms/5QhDt8ZurRhhcjvD2 Kindly fill the health information so that I can advice best products to you thanks Can a complete remedy medicine be expected for hepatitis b disease in coming years? This is my result is there any chance of me naturally become hepatitis b negative? IgM anti HBcAg, LFT ultrasound abdomen n HBV viral load(quantitative) HbeAg required to know whether it is chronic infection or carrier state Hepatitis b disise medicine&#x27;s explain Hepatitis b disise medicine&#x27;s explain https://www.1mg.com/otc/liv.52-hb-capsule-otc122387One ?one tablet morning & evening after taking food , use at least 1-2 monthsuse along with your treatment i have unprotected sex with my friend. Can I take any drugs now to prevent any STD/HIV infection Hello PATIENT to 1mg. There is some medicine for prophylactic but you need to see physician for prescription and better you check HIV status of both partner