Generic
Timolol Maleate 0.5% + Travoprost 0.004% Eye Prep
At a glance
Timolol Maleate 0.5% + Travoprost 0.004% Eye Drop is used for glaucoma and ocular hypertension. It lowers eye pressure by reducing aqueous humor production and increasing outflow.
Description
Timolol Maleate 0.5% + Travoprost 0.004% is a combination of timolol (beta-blocker) and travoprost (prostaglandin analog). Timolol reduces aqueous humor production; travoprost increases uveoscleral outflow. Together, they effectively lower intraocular pressure.
Indications
- Glaucoma
- Ocular hypertension
Therapeutic class
Drugs for Miotics and Glaucoma
Pharmacological class
Beta-Blocker + Prostaglandin Analog
Pharmacology
Timolol blocks beta-adrenoceptors, reducing aqueous humor production; travoprost activates FP prostanoid receptors, increasing uveoscleral outflow. The combination effectively lowers intraocular pressure.
Mechanism of action
Lowers intraocular pressure by reducing aqueous humor production and increasing outflow.
Dosage
Adult Dose (Ophthalmic):
- 1 drop in affected eye(s) once daily in the evening
Administration
- For ophthalmic use only
- Wash hands before use
- Do not touch dropper tip to eye or any surface
- Wait 5 minutes before other eye medications
Missed dose
If you miss a dose, apply it the next evening; do not double the dose.
Side effects
Common Side Effects:
- Eye pain, itching, burning
- Change in iris color
- Foreign body sensation
- Darkening of eyelashes
Precautions & warnings
- Visual disturbances may affect driving or operating machinery
- Caution in asthma, COPD, or heart disease
- Apply pressure to the inner corner of the eye for 1 minute after instillation
Contraindications
- Hypersensitivity to any component
Drug interactions
No significant drug interactions known.
Food interactions
Alcohol consumption is not relevant (topical application).
Use in pregnancy
Use in Pregnancy: May be unsafe; animal studies show harmful effects; use only if clearly needed; consult your doctor.
Pregnancy Category: C — always consult a doctor before taking during pregnancy.
Use in lactation
Use in Lactation: Probably safe; limited data suggests no significant risk; consult your doctor.
Pediatric use
Safety and efficacy not established in children
Geriatric use
Caution required in elderly patients
Renal / hepatic impairment
Renal Impairment: Not applicable (topical application)
Hepatic Impairment: Not applicable (topical application)
Overdose effects
Overdose is not applicable (topical application); excessive use may cause eye irritation.
Storage conditions
Store in a cool and dry place, protected from light; keep out of reach of children.
Chemical structure
Timolol + Travoprost