Flunid

• Skin and Soft Tissue Infections: Boils, abscess, carbuncles, infected skin conditions, cellulitis, infected wounds, burns, otitis media and externa, impetigo.
• Respiratory Tract Infections: Pneumonia, lung abscess, empyema, sinusitis, pharyngitis, tonsillitis, quinsy.
• Other Infections: Osteomyelitis, enteritis, endocarditis, urinary tract infection, meningitis, septicaemia.

Flucloxacillin is active against Gram-positive organisms including penicillinase producing strains. Flucloxacillin acts by inhibiting the formation of cell wall of bacteria. Flucloxacillin is isoxazolyl penicillin which combined the properties of resistance to hydrolysis by penicillinase, gastric acid stability and activity against gram-positive bacteria.

Adult Dose (Oral):

• 250-500 mg 3-4 times daily; dosage may be doubled in severe infections.
• Osteomyelitis and endocarditis: up to 8 g/day in 6-8 hourly divided doses.

Adult Dose (Parenteral):

• IV: 0.25-1 g 4 times/day; may double in severe cases.
• IM: 250 mg 4 times daily.

Child Dose (2-10 years): Half of adult dose; (<2 years): One fourth of adult dose.

Common Side Effects:

• Nausea
• Vomiting
• Diarrhea
• Allergic reaction
• Injection site reactions (pain, swelling, redness)
• Rash, urticaria
• Fever

Use in Pregnancy: Category B; generally considered safe during pregnancy; animal studies have shown low or no adverse effects.

Precautions:

• Flucloxacillin does not usually affect your ability to drive.
• Prescribed for bacterial infections; finish the prescribed course (do not stop early even if feeling better).
• Diarrhea may occur as a side effect; should stop when course is complete; inform doctor if blood in stools.
• Inform doctor immediately if itchy rash, swelling of face, throat or tongue, or breathing difficulties occur.
• Use with caution in patients with hepatic dysfunction and allergic diathesis.

Overdose: Limited information on overdose; symptomatic treatment.

Storage: Keep in a dry place away from light and heat. Keep out of reach of children.