osudhkosh
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Company•The ACME Laboratories Ltd.

Rebreath Nebuliser Solution

175 mg/3 mlOTC
Generic: Revefenacin

৳ 80/unit

Pack: ৳ 240

Nebuliser SolutionStrip (3 3ml Ampoule)
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At a glance

Revefenacin is a long-acting muscarinic antagonist (LAMA) used for the maintenance treatment of chronic obstructive pulmonary disease (COPD). It is inhaled once daily via nebulizer and provides bronchodilation.

Indications
  • Maintenance treatment of chronic obstructive pulmonary disease (COPD)
Pharmacology

Revefenacin is a long-acting muscarinic antagonist with similar affinity for M1-M5 receptors. It inhibits M3 receptors on airway smooth muscle, causing bronchodilation. Preclinical models showed dose-dependent prevention of methacholine- and acetylcholine-induced bronchoconstrictive effects lasting over 24 hours.

Dosage

Adult Dose (Inhalation):

  • COPD maintenance: 175 mcg (one unit-dose vial) once daily via nebulizer using a mouthpiece
  • Administer at the same time each day
  • Hepatic impairment: Safety not evaluated; not recommended in any degree of hepatic impairment
  • Renal impairment: No dosage adjustment required
Side effects

Side Effects (1-10%):

  • Cough (4%)
  • Nasopharyngitis (4%)
  • Headache (4%)
  • Upper respiratory tract infection (3%)
  • Back pain (2%)
  • Hypertension (1-2%)
  • Dizziness (1-2%)
  • Oropharyngeal pain (1-2%)
  • Bronchitis (1-2%)
Use in pregnancy

Use in Pregnancy: No data on use in pregnant women; advise to contact physician if pregnancy occurs; animal studies showed no evidence of fetal harm.

Pregnancy Category: C — always consult a doctor before taking during pregnancy.

Precautions & warnings
  • Do not initiate during acutely deteriorating or life-threatening COPD episodes
  • Intended for maintenance treatment; not for relief of acute symptoms
  • Paradoxical bronchospasm may occur (life-threatening); treat with short-acting bronchodilator and discontinue
  • Caution in narrow-angle glaucoma (eye pain, blurred vision, visual halos) and urinary retention (prostatic hyperplasia)
  • Immediate hypersensitivity reactions: Discontinue
Overdose effects

Overdose: Anticholinergic signs and symptoms (nausea, vomiting, dizziness, blurred vision, increased intraocular pressure, fatigue, difficulty voiding); treatment: symptomatic supportive care.

Storage conditions

Store below 30°C in a dry place, protected from direct sunlight; discard ampoule and other part after use; keep out of reach of children.

Revefenacin — see the full informationPharmacology, precautions, pregnancy, overdose and the rest on the generic page
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.