৳ 3.10/unit
Pack: ৳ 186
৳ 3.10/unit
Pack: ৳ 186
At a glance
Levothyroxine Sodium is a medicine used to treat an underactive thyroid gland (hypothyroidism). It replaces the hormone which was not being produced by your thyroid gland in sufficient quantity and helps regulate your body's energy and metabolism.
Indications
- Hypothyroidism - replacement therapy of any etiology
- Suppression of Thyroid Stimulating Hormone (TSH) levels - goitres, nodules, and after treatment of thyroid cancer
- Suppression of goitrogenic effects of other drugs (e.g., lithium)
- Diagnostic aid in suppression tests
Pharmacology
Levothyroxine Sodium is a synthetic thyroxine identical to natural T4. It increases basal metabolic rate (BMR) and utilization and mobilization of glycogen stores and stimulates protein synthesis. These effects are mediated at the cellular level by the thyroxine metabolite, tri-iodothyronine (T3).
Dosage
Adult Dose (Oral):
- Mild Hypothyroidism: 1.7 mcg/kg or 100-125 mcg daily; max 300 mcg/day
- >50 years or with CVD: 12.5-25 mcg daily start; adjust 12.5-25 mcg every 4-6 weeks
- Severe Hypothyroidism: 12.5-25 mcg daily start; increase 25 mcg every 2-4 weeks
- TSH suppression in thyroid cancer: >2 mcg/kg/day
Pediatric Dose: 0-3 months: 10-15 mcg/kg/day; 3-6 months: 8-10; 6-12 months: 6-8; 1-5 years: 5-6; 6-12 years: 4-5; >12 years: 2-3 mcg/kg/day
Side effects
Common Side Effects (due to overdose):
- Palpitations
- Vomiting
- Anxiety
- Diarrhea
- Flushing
- Weight loss
- Nervousness
- Restlessness
Use in pregnancy
Use in Pregnancy: Levothyroxine Sodium is safe during pregnancy (Category A). Low or no risk to the developing baby. Dose may need to be increased during pregnancy.
Pregnancy Category: A — always consult a doctor before taking during pregnancy.
Precautions & warnings
- Monitor thyroid hormone levels regularly
- Dose adjustment needed with weight changes
- Maintain 4-hour gap with antacids, calcium, or iron supplements
- Inform doctor before changing brand
- Dose may need to be increased during pregnancy
Overdose effects
Overdose symptoms: agitation, confusion, irritability, hyperactivity, headache, sweating, tachycardia, arrhythmias, coma. Symptomatic treatment.
Storage conditions
Store below 30°C in a dry place, protected from light; keep out of reach of children.