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Generic

Adalimumab

3 brands available in the market

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BrandCompanyFormPrice/unit
Advixa 4040mg/0.4mlIncepta Pharmaceuticals Ltd.Injection৳ 8,000
Adalimab 4040mg/0.8mlHealthcare Pharmaceuticals Ltd.Injection৳ 15,000
Advixa 4040mg/0.8mlIncepta Pharmaceuticals Ltd.Injection৳ 15,000

At a glance

Adalimumab — brands, prices, indication, dosage and side effects available in Bangladesh.

Description

Adalimumab is a medicine used to treat a variety of conditions such as ankylosing spondylitis, rheumatoid arthritis, psoriasis, ulcerative colitis, and Crohn’s disease. It provides relief from swelling, pain, and redness associated with various disorders and improves physical function. Adalimumab is given by a healthcare professional and should not be self-administered. You should use it regularly and at the same time each day to get the maximum benefit from it. Continue using it as recommended by your doctor and complete the dose even if you feel better. Some of the common side effects of this medicine include headache, sinus inflammation, rash upper respiratory tract infection, and injection site reactions such as pain, redness, and swelling. Talk to your doctor if any of these side effects do not go away with time or get worse. Your doctor may help with ways to reduce or prevent these symptoms. To make sure the medicine is safe for you, before taking it, let your doctor know if you have any problems with your heart, kidneys, or liver. You should also tell your doctor about all the other medicines you are taking. It is important for pregnant and breastfeeding women to ask the advice of their doctors before taking this medicine. Adalimumab blocks the action of certain chemical messengers that are responsible for inflammation, swelling and redness associated with certain joint diseases.

Indications

• Ankylosing spondylitis • Rheumatoid arthritis • Psoriasis • Ulcerative Colitis • Crohn’s disease

Mechanism of action

Adalimumab is a recombinant DNA-derived human Ig G1 monoclonal antibody. It binds to human tumour necrosis factor alfa (TNF-alpha), thus interfering w/ cytokine-driven inflammatory processes.

Dosage

Adult Dose: Subcutaneous Rheumatoid arthritis, Ankylosing spondylitis, Psoriatic arthritis Adult: 40 mg as a single dose every other wk. May increase to wkly dosing when used as monotherapy. Crohn's disease, Ulcerative colitis Adult: Moderate to severe active disease: Initially, 160 mg (given as four 40-mg inj in 1 day or as two 40-mg inj for 2 consecutive days), then 80 mg 2 wk after the initial dose (day 15). Maintenance: After 2 wk (day 29), 40 mg every other wk, may increase to 40 mg wkly if needed. Review treatment if no response w/in 8 (ulcerative colitis) or 12 (Crohn's disease) wk of therapy. Plaque psoriasis Adult: Initially, 80 mg. Maintenance: 40 mg every other wk beginning 1 wk after 1st dose. Child Dose: Subcutaneous Juvenile idiopathic arthritis Child: >4 yr 15 to 30 kg: 40 mg every other wk.

Administration

Your doctor or nurse will give you this medicine. Kindly do not self administer.

Missed dose

If you miss a dose of Adalimumab, please consult your doctor.

Side effects

Common: • Headache • Sinus inflammation • Rash • Upper respiratory tract infection • Injection site reaction

Precautions & warnings

[UNSAFE] Adalimumab may cause side effects which could affect your ability to drive. Adalimumab may cause room spinning sensation and vision disturbances. This may affect your driving ability. It is given by injection under the skin (via subcutaneous). Take it as per the dose and duration suggested by the doctor. Inform your doctor immediately if you notice severe rash, hives, swelling of hands or face and shortness of breath. Store the pen in the refrigerator. When refrigeration is not possible, you can also keep your pen at room temperature (less than 30°C) for up to 2 weeks. Do not freeze it. Do not stop taking the medication suddenly without talking to your doctor first.

Contraindications

None listed on FDA-approved label.

Drug interactions

Increased risk of serious infections w/ other biologic disease-modifying antirheumatic drugs (e.g. abatacept, anakinra), rituximab. May increase immunosuppressant effect w/ tocilizumab, live vaccines.

Food interactions

[SAFE] Consuming alcohol with Adalimumab does not cause any harmful side effects.

Use in pregnancy

[SAFE IF PRESCRIBED] Adalimumab is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Use in lactation

[SAFE IF PRESCRIBED] Adalimumab is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Renal / hepatic impairment

[CONSULT YOUR DOCTOR] There is limited information available on the use of Adalimumab in patients with kidney disease. Please consult your doctor. [CONSULT YOUR DOCTOR] There is limited information available on the use of Adalimumab in patients with liver disease. Please consult your doctor.

Common questions

Suffering from ulcerative colitis in large intestine bleeding in stool, acute acidity for acidity take Neksium 40mg once daily in empty stomach for 10 daysfor rest problem consult surgeon or Gastroentrologist Suffering from ultratics colitis i have done colonoscopy test 04 months back From 05 months how many months I have to take medicines is it cure completely Ulcerative colitis is a lifelong disease with remission and exacerbations. Durations of remission cant b predicted all d time Hi, I was diagnosed for Ulcerative Colitis in 2009. I was administered with Mesacol , I was back to normal. In past 1 month , after having food lunch or dinner I feel uneasy such as indigestion, having to force for motions next day. Sometimes Iam unable to pass motions. I feel tired also. Pls suggest. Ulcerative colitis is a lifong disease q with remission and exacerbation . U should b under constant follow up of ur gastroenterologist Is there any medicine for ulcerative colitis Hi ulcerative colitis can be managed by diet control & some ayurvedic medicine . Permanent Cure for ulcerative colitis https://goo.gl/forms/5QhDt8ZurRhhcjvD2 Kindly fill the health information so that I can advice best products to you thanks I am a ulcerative colitis patient https://goo.gl/forms/5QhDt8ZurRhhcjvD2 Kindly fill the health information so that I can advice best products to you thanks Suffering from severe lower back pain since 6 years. As per MRI it is lumbar spondylosis,but Doctor told that it is one of the types of arthritis in which bridge is getting formed on spine Is there any permanent solution .at present taking Sazo 500 twice a day It's called Ankylosing spondylitis". no permanent cure for this All you need to do is to exercise each and every joint of your body regularly "Along with the medication Suffering from Ulcerative colitis since 5 years Take butter milk at the time of lunch dailyhttp://www.1mgayush.com/products/bael/Standard

⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.
Adalimumab — দাম, ব্যবহার, ডোজ ও পার্শ্বপ্রতিক্রিয়া | oshudhkosh