Generic
Aluminium Chloride Hexahydrate 20%
2 brands available in the market
At a glance
Aluminium Chloride Hexahydrate topical solution is indicated for the treatment of hyperhidrosis of the armpits, hands, and feet.
Description
Acts locally in the stratum corneum and sweat ducts to form a gel plug that blocks sweat output for hyperhidrosis management.
Indications
Treatment of hyperhidrosis of the armpits (axillae), the hands and the feet.
Pharmacological class
Antiperspirant Topical Solution
Pharmacology
Precipitates with mucopolysaccharides, damaging epithelial cells and forming a plug that blocks sweat output.
Mechanism of action
Obstruction of sweat gland ducts via aluminium-mucopolysaccharide gel plug formation.
Dosage
Apply each night until sweating stops, then reduce frequency to twice a week or less.
Administration
Apply topically at night to thoroughly dried skin and wash off in the morning.
Missed dose
Apply when remembered, avoiding daytime re-application.
Drug interactions
No known drug interactions.
Food interactions
Not applicable.
Contraindications
Hypersensitivity to the active substance or excipients.
Side effects
Very common: Application site irritation. Pruritus, erythema, rash, and skin burning sensation.
Use in pregnancy
Unlikely to penetrate skin; no effects during pregnancy anticipated.
Pregnancy Category: N/A (Topical) — always consult a doctor before taking during pregnancy.
Use in lactation
Ensure breast is free of solution before feeding.
Precautions & warnings
Ensure skin is completely dry to prevent hydrochloric acid formation. Do not apply on shaved or broken skin.
Pediatric use
Use as directed by physician.
Geriatric use
Safe for older adults.
Renal / hepatic impairment
Not applicable.
Overdose effects
Frequent application increases skin irritation. Ingestion may cause GI burning and symptoms.
Therapeutic class
Miscellaneous topical agents
Storage conditions
Store below 25°C, protected from light, upright, away from naked flame.
Chemical structure
Aluminium Chloride Hexahydrate