Amisulpride

Amisulpride is a prescription medicine used in the treatment of schizophrenia, a mental disorder that can result in hallucinations or delusions and also adversely affects a person’s ability to think and behave. Amisulpride may be taken with or without food, preferably before bedtime. However, it is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration as advised by your doctor and if you have missed a dose, take it as soon as you remember. Do not skip any doses and finish the full course of treatment even if you feel better. It is important that this medication is not stopped suddenly without talking to your doctor as it may worsen your symptoms. Some common side effects of this medicine include nausea, vomiting, and dryness in the mouth. Initially, this medicine may cause a sudden drop in blood pressure when you change positions, so it is better to rise slowly if you have been sitting or lying down. It also causes dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. This medicine can lead to weight gain and may increase your blood sugar and cholesterol levels. However, modifying your lifestyle by having a healthy diet and exercising regularly can reduce this side effect. Amisulpride is an atypical antipsychotic. It works by modulating the action of certain chemical messengers in the brain that affect thoughts.

• Schizophrenia

Amisulpride binds selectively with a high affinity to human dopaminergic D2/D3 receptor subtypes whereas it is devoid of affinity for D1, D4 and D5 receptor subtypes.

Adult Dose: Adult Acute episodes, 400—800mg daily in two divided doses. Adjust according to response; max 1.2g daily. Mixed positive and negative symptoms, adjust dose to control positive symptoms. Predominant negative symptoms, 50—300mg once daily. Elderly: Dose reduction may be required. Hepatic Failure: Since the drug is weakly metabolised a dosage reduction should not be necessary. Child Dose: Under 18 years, not recommended. Renal Dose: Amisulpride is eliminated by the renal route. In renal insufficiency, the dose should be reduced to half in patients with creatinine clearance (CRCL) between 30-60 ml/min and to a third in patients with CRCL between 10-30 ml/min. As there is no experience in patients with severe renal impairment (CRCL < 10 ml/min) particular care is recommended in these patients

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Amisulpride may be taken with or without food, but it is better to take it at a fixed time.

Common: • Nausea • Vomiting • Dryness in mouth • Constipation • Weight gain • Decreased blood pressure • Dystonia (involuntary muscle contractions) • Akathisia (inability to stay still) • Parkinsonism • Increased prolactin level in blood

[UNSAFE] Amisulpride may cause side effects which could affect your ability to drive. You may feel less alert, drowsy or sleepy while taking this medicine. This may affect your driving ability. Amisulpride helps treat schizophrenia. Take it at bedtime to avoid feeling sleepy during the day. Use caution while driving or doing anything that requires concentration as Amisulpride can cause dizziness and sleepiness. To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down. Do not consume alcohol while on treatment with this medicine as it may worsen the side effects. It may cause increased weight, blood sugar, cholesterol, and triglycerides (fat) levels. Eat healthy and exercise regularly. Inform your doctor if you are pregnant, planning to conceive or breastfeeding. Do not stop taking Amisulpride without talking to your doctor first as it may cause worsening of symptoms.

Prolactin-dependent tumours, phaeochromocytoma. Lactation.

Other antipsychotics, drugs that prolong QT interval, levodopa, CNS depressants, alcohol, antihypertensives.

[UNSAFE] It is unsafe to consume alcohol with Amisulpride.

[CONSULT YOUR DOCTOR] Amisulpride may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

[CONSULT YOUR DOCTOR] Amisulpride is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

[CAUTION] Amisulpride should be used with caution in patients with kidney disease. Dose adjustment of Amisulpride may be needed. Please consult your doctor. Use of Amisulpride is not recommended in patients with severe kidney disease. [SAFE IF PRESCRIBED] Amisulpride is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Amisulpride may not be needed in these patients. Please consult your doctor.

Sulpitac 50 may reduced For considering Dear 1mg user, medicines gives quick relief and has side effects too so consult your doctor and see how to reduce dose and control totally, later you can take counselling that really helps you. Pay Rs 99 and call me on my phone www.dontfeel.com for counselling Now I take the medicine oxetol 600, ativan2, sulpitac 100 .sir I have social anxiety. Any solution sir Start tab censpram 5 mg daily even take a sulpitac od 100 and emetil 75 in morning and haloperidol 5 mg and peptin 2 mg no change in thinking Response to medicines depends on- 1. Diagnosis 2. Adequate dose of medicines 3. Adequate duration of treatment 4. Regular Medicines 5. Individual factors like patient&#x27;s metabolism, other medical conditions etc. Resistance to medicines can be because of following factors- 1. Diagnostic confusion 2. Irregular treatment or lack of proper follow up with treating doctor 3. Inadequate dose of medicines 4. Pharmacodynamics/ pharmacokinetics 5. Internal biological resistance For Treatment Resistant Depression , adjunctive measures like changing treatment goals, psychotherapy and ECTs can Sir I am suffering with social anxiety. I have no courage to face and speak with people.sir now I take the medicine sulpitac 100mg,oxetol 600mg and ativan 2mg. Based on your clinical history, your doctor plans the type of medicine and it&#x27;s dose and duration. For first episode of anxiety/ depression/ panic, the usual maintenance phase is 6 months of asymptomatic period, after which medicines can be gradually tapered. But treatment may need to continue longer depending on severity and frequency of episodes. To take any decision to change medication or stop them, several factors have to be taken in account for which regular follow up with your psychiatrist is important. For second opinion, seek a proper consultation with another psychiatrist and take along your previous prescriptions. Sir I am suffering with social anxiety. Now I am taking the medicine oxetol 600mg,sulpitac 100mg and ativan2mg.no improvement sir.please tell me any other medication sir? censpram 10 mg daily How to treat erectile dysfunction with schizophrenia https://www.1mg.com/otc/himalaya-confido-tablet-otc90667One ?one tablet morning & evening after taking food , use at least 1-2 months Continuously hearing voices of unknown people when nobody is there and very suspicious and thinks that nabors trying to hurt. Taking following medicins Thyronorm 75, Epition 1 Tab, Sulpitac 600 mg Imagining things, seeing or hearing things that normally people can&#x27;t, behavioural disturbances like unprovoked anger or irritability, fear, suspiciousness can be symptoms of serious psychiatric illness. False, firm beliefs that someone may want to harm/ hurt, that people constantly talk about one or are trying to do something harmful, with or without hearing strange voices that only the patient an hear is called paranoid psychosis.It is a neurochemical disorder and needs proper evaluation and treatment by a psychiatrist. She is having a mental problem she mummers the whole day and cries and laughs without any reason i have consulted a psychatrist and i am giving sulpitac now And she us having continuous vomiting Response to medicines depends on- 1. Diagnosis 2. Adequate dose of medicines 3. Adequate duration of treatment 4. Regular Medicines 5. Individual factors like patient&#x27;s metabolism, other medical conditions etc.Please discuss with your psychiatrist regarding vomiting issues