Generic
Armodafinil
2 brands available in the market
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| Brand | Company | Form | Price/unit |
|---|---|---|---|
| Armoda150 | ACI Limited | Tablet | ৳ 15 |
| Uptiva 150150mg | Incepta Pharmaceuticals Ltd. | Tablet | ৳ 15 |
At a glance
Armodafinil — brands, prices, indication, dosage and side effects available in Bangladesh.
Description
Armodafinil is a prescription medicine used in the treatment of excessive daytime sleepiness (narcolepsy). It improves wakefulness and helps you to stay awake and reduces the tendency to fall asleep during the day, thus restoring the normal sleep cycle. Armodafinil may be taken with or without food. It is advised to take this medicine at a fixed time each day to maintain a consistent level in the blood. If you miss any doses, take it as soon as you remember. Do not skip any doses and finish the full course of treatment even if you feel better. It is important that this medication is not stopped suddenly as it may worsen your symptoms. Some common side effects of this medicine include headache, nausea, and insomnia (difficulty sleeping). It even causes dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. However, these side effects are temporary and usually resolve on their own in some time. Please consult your doctor if these do not subside or bother you. Always remember that this medicine only used when advised by a doctor as it is not a replacement for a good sleep routine. You should try to get the right amount of sleep every night. Before taking Armodafinil, inform your doctor if you have any problems with your kidneys, heart, liver, or have a history of seizures (epilepsy or fits). Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or if you have any suicidal thoughts. Armodafinil modulates the levels of chemical messengers in the brain and exerts a stimulant effect to reduce extreme sleepiness.
Indications
• Narcolepsy (Uncontrollable daytime sleepiness)
Mechanism of action
The mechanism of armodafinil is unknown but it appears to exert its stimulant effects by reducing GABA-mediated neurotransmission.
Dosage
Adult Dose: Oral Narcolepsy, Obstructive sleep apnoea Adult: 150-250 mg daily as a single dose in the morning or in 2 divided doses (in the morning and at midday). Shift Work Sleep Disorder 150 mg PO qDay 1 hour prior to patient's work shift Elderly: Consider lower initial dose Hepatic impairment: Reduce dose Child Dose: Safety and efficacy not established Renal Dose: Renal impairment: Safety and efficacy not established
Administration
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Armodafinil may be taken with or without food, but it is better to take it at a fixed time.
Missed dose
If you miss a dose of Armodafinil, skip it and continue with your normal schedule. Do not double the dose.
Side effects
Common: • Headache • Dizziness • Nausea • Insomnia (difficulty in sleeping)
Precautions & warnings
[UNSAFE] Armodafinil may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur. Patients to be advised to avoid driving or any other potentially dangerous activity. Take it with or without food, preferably in morning time before you need to be alert. It is not a replacement for a good sleep routine. Try to get the right amount of sleep every night. It may cause headaches. Drink plenty of water and take a suitable pain killer. Inform your doctor if it does not go away. Do not drive or do anything requiring concentration until you know how it affects you. Your doctor may monitor you for heart disease and blood pressure while taking this medicine. It makes contraceptive pills less effective, consult with a doctor for effective contraception. Avoid taking alcohol while taking this medicine as it may lead to increase side effects. Inform your doctor if you are pregnant, planning to conceive or breastfeeding. Talk to your doctor if you notice sudden mood changes or develop suicidal thoughts. Stop taking medication and inform your doctor if you experience rash, itching or breathing problem while taking this medicine. Inform your doctor if you had a history of depression, anxiety, mood disorder, or mania and drug abuse. Inform your doctor if you notice difficulty sleeping, diarrhea, hallucinations, nausea, chest pain, and fast or slow heart rate. It may cause addiction/ dependence potential when taken for long term. Do not stop taking the medication suddenly without talking to your doctor.
Contraindications
Uncontrolled moderate to severe hypertension or cardiac arrhythmias; history of left ventricular hypertrophy or ischaemic ECG changes, chest pain, any clinical signs of mitral valve prolapse.
Drug interactions
May increase metabolism of ciclosporin, oral contraceptives. May increase the levels/effects of warfarin, TCAs and CYP2C19 substrates (e.g. citalopram, diazepam, methsuximide, phenytoin, propranolol, sertraline). Levels/effects may be reduced with CYP3A4 inducers (e.g. aminoglutethimide, carbamazepine, nafcillin, nevirapine, phenobarbital, phenytoin, rifamycins). Levels/effects may be increased with CYP3A4 inhibitors (e.g. azole antifungals, clarithromycin, diclofenac, doxycycline, erythromycin, imatinib, isoniazid, nefazodone, nicardipine, propofol, protease inhibitors, quinidine, telithromycin, verapamil). Avoid alcohol.
Food interactions
[UNSAFE] It is unsafe to consume alcohol with Armodafinil.
Use in pregnancy
[CONSULT YOUR DOCTOR] Armodafinil may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Use in lactation
[CONSULT YOUR DOCTOR] Armodafinil is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Renal / hepatic impairment
[CONSULT YOUR DOCTOR] There is limited information available on the use of Armodafinil in patients with kidney disease. Please consult your doctor. [CONSULT YOUR DOCTOR] There is limited information available on the use of Armodafinil in patients with liver disease. Please consult your doctor.
Common questions
Main problem : I keep feeling too sleepy throughout the day. I have so many things to do related to my career, family and social life but this problem has been consuming most of my quality time, brings down my energy making me too less productive. I have been reading about this thing over Internet and what I can figure out myself is that my problem seems to be too close to Narcolepsy. Narcolepsy is sudden uncontrollable bout of sleepiness. Often sleep problems are due to poor quality of night time sleep. You may go for a sleep study or polysomnography to identify sleep related issues and tackle the problem easily. palpitation tachycardia hypertension loud snoring daytime sleepiness Anxiety is the result of a hyperarousal state of nervous system due to a low threshold for threat perception. In simpler words, it's an ongoing flight or fight response. It can elicit a neuro-hormonal response understood as Flight or Fright reaction kicking in physiological cascade of symptoms ranging from palpitations, tachycardia, breathlessness, increased bowel movement, increase frequency of urination, dizziness, muscle tension or pain, trembling, dizziness, blurring of vision to restlessness, confusion and fainting spells. Chronic stress causes prolonged anxiety response with the consequences of slowed cognition , lack of concentration, headaches, fluctuations in blood pressure, irritable bowel syndrome with persistent Bowel movement issues and increased wear and tear of body tissues. Identifying your stressors, learning to deal with them, de stressing regularly by doing something that makes one feel good, yoga and meditation are some non pharmacological strategies to deal with it. If the condition is persisting for a long time, it's better to see a psychiatrist. Needs any kind of injection to ward of weakness. Weakness is so much that she can't get up from bed. All time sleeping Ezeepam plus tablet can cause sleepiness I have adhd and excessive daytime sleepiness and have been wanting to try modalert can I get a prescription Unfortunately Indian law does not allow giving prescription without actually examining patient. Please visit nearest psychiatrist for same. Med for uncontrollable shivering Should I continue same tablet 'petril beta 10' u can but consult Neuro I got my body tests done and found testosterone below the minimum range. Please advice. Take inj sustonone 250mg depot once a month Is tablet TRANESMA (Tranexamic Acid Tablet IP 250mg) anyway related for treatment of Melasa or Face pigmentation. Yes It can be used