Generic
Astaxanthin
25 brands available in the market
At a glance
Astaxanthin is a powerful antioxidant that improves cardiovascular health, protects skin, prevents cataracts and macular degeneration, and reduces inflammation.
Description
Astaxanthin is a xanthophyll carotenoid with antioxidant and anti-inflammatory properties. It has potential as a therapeutic agent in atherosclerotic cardiovascular disease.
Similar in structure to beta-carotene, astaxanthin can quench, scavenge and trap free radicals including singlet and triplet oxygen. It prevents lipid peroxidation and enhances the protective capacities of other antioxidants in the body.
The recommended daily dosage is 2-4 mg daily. Depending on dosage, it works on cardiovascular health, skin, nervous system, eyes, inflammation, and fertility.
Indications
- Strong antioxidant
- Improves cardiovascular health (atherosclerosis, reduce cholesterol)
- Improves immune function
- Improves skin condition and protects from sun damage
- Improves recovery from central nervous system injuries
- Protects from Parkinson's, dementia and Alzheimer's disease
- Protects eyes from cataracts and macular degeneration
- Reduces inflammation (arthritis)
- Reduces risk of infertility
- Reduces oxidative DNA damage and cancer risk
- Stabilizes blood sugar
Therapeutic class
Supplements & adjuvant therapy
Pharmacological class
Xanthophyll Carotenoid (Antioxidant)
Pharmacology
Astaxanthin is a xanthophyll carotenoid with antioxidant and anti-inflammatory properties. It acts as an antioxidant by dual mode of action - suppressing singlet oxygen and inhibiting lipid peroxidation.
Astaxanthin is absorbed by passive diffusion into the intestinal epithelium alongside fatty acids. It is incorporated into lipoproteins, transported to the liver via lymph and blood, and partly resecreted with lipoproteins. More than 70% of astaxanthin is contained in HDL portion of plasma.
Mechanism of action
Astaxanthin suppresses singlet oxygen and inhibits lipid peroxidation, reducing harmful free radicals. Instead of sacrificing an electron, it stabilizes metabolic toxin radicals by adding them to its double-bonded chain. It stops and reverses oxidative damage to cell structures and protects healthy forms of cholesterol.
Dosage
Adults (18 years and older):
- 4 mg daily: Strong antioxidant, improves cardiovascular health, improves immune function
- 4-8 mg daily: Improves skin condition, protects from sun damage, improves CNS recovery, protects from cataracts and macular degeneration
- 8-12 mg daily: Reduces inflammation (arthritis)
- 16 mg daily: Reduces risk of infertility
Take with or immediately prior to meals in the morning.
Administration
Take with meals or immediately before meals in the morning. Swallow the capsule whole.
Missed dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
Side effects
No severe side effects have been reported yet.
Precautions & warnings
Precautions:
- Avoid if known allergy to astaxanthin
- Pregnant women and nursing mothers should avoid astaxanthin supplements (no safety data available)
- Safe when consumed in amounts found in food; supplement safety is unknown
Contraindications
- Known hypersensitivity to astaxanthin
Drug interactions
- Cholestyramine, Colestipol, Mineral Oil, Orlistat: May reduce astaxanthin absorption rate
Food interactions
Best taken with food for better absorption.
Use in pregnancy
[CONSULT YOUR DOCTOR] Pregnant women should avoid astaxanthin supplements as no safety data is available.
Use in lactation
[CONSULT YOUR DOCTOR] Nursing mothers should avoid astaxanthin supplements as no safety data is available.
Pediatric use
Dosage for children has not been established. Do not use without medical advice.
Geriatric use
Adult dosage applies to elderly patients.
Renal / hepatic impairment
No dose adjustment needed for patients with kidney or liver disease.
Overdose effects
No case of overdose has occurred with astaxanthin.
Storage conditions
Store in a cool and dry place, away from direct light. Keep out of reach of children.
Chemical structure
Astaxanthin (C₄₀H₅₂O₄)