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Generic

Atropine Sulphate 1% eye prep

13 brands available in the market

At a glance

Atropine Sulphate 1% eye prep is an anticholinergic agent used for mydriasis and cycloplegia.

Description

Atropine is an anticholinergic agent which competitively blocks the muscarinic receptors in peripheral tissues. It also has mydriatic and cycloplegic effect.

Indications
  • Keratitis
  • Iritis
  • Cyclitis
  • Refractive procedure in children
  • Mydriasis and cycloplegia
Therapeutic class

Anticholinergics

Pharmacological class

Anticholinergic Agent

Pharmacology

Atropine is an anticholinergic agent which competitively blocks the muscarinic receptors in peripheral tissues.

Mechanism of action

Atropine blocks muscarinic receptors, causing pupillary dilation and ciliary muscle paralysis.

Dosage

Adult - Inflammatory eye disorders: 1-2 drops of 1% solution up to 4 times daily.
Adult - Eye refraction: 1 drop of 1% solution twice daily for 1-2 days before procedure.
Child - Inflammatory eye disorders: 1 drop of 1% solution up to 3 times daily.
Child - Eye refraction: 1-2 drops of 0.5% solution twice daily for 1-3 days before procedure.

Administration

For ophthalmic use only. Hold the dropper close to the eye without touching it.

Missed dose

If you miss a dose, apply it as soon as possible. However, if it is almost time for your next application, skip the missed dose.

Side effects

Common: Eye irritation, hyperemia, edema, dry eyes, dermatitis, blurred vision, increased intraocular pressure.
Serious: Systemic toxicity in children.

Precautions & warnings

Toxic systemic reaction may occur in the very young and very old. Children are at higher risk of systemic toxicity.

Contraindications

Narrow angle glaucoma.

Drug interactions

Quinidine, antidepressants, some antihistamines: Additive anticholinergic effects.

Food interactions

Can be used with or without food.

Use in pregnancy

Pregnancy Category C. Atropine may be unsafe during pregnancy.

Pregnancy Category: C — always consult a doctor before taking during pregnancy.

Use in lactation

Trace amounts enter breast milk. AAP Committee states 'compatible with nursing'; use with caution.

Pediatric use

Children are at higher risk of systemic toxicity.

Geriatric use

Elderly patients are at higher risk of toxic systemic reactions.

Renal / hepatic impairment

No special precautions necessary.

Overdose effects

Excessive use may cause systemic toxicity.

Storage conditions

Store in a cool and dry place, protected from light. Keep out of reach of children.

Chemical structure

Atropine Sulphate 1% eye prep

Common questions

What is it used for?
It is used for keratitis, iritis, cyclitis, and refractive procedures.
What is the dosage?
Adults: 1-2 drops up to 4 times daily; Children: 1 drop up to 3 times daily.
What are the common side effects?
Eye irritation, blurred vision, increased intraocular pressure.
Who should not use it?
Patients with narrow angle glaucoma.
Can it be used during pregnancy?
Pregnancy Category C, consult your doctor.
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.