Generic
Benzydamine + Chlorhexidine gluconate
2 brands available in the market
At a glance
Benzydamine + Chlorhexidine gluconate is an anti-inflammatory antiseptic solution used for the relief of pain and inflammation in mouth and throat conditions.
Description
Benzydamine is an NSAID that reduces pain and inflammation by reducing the production of hormone-like substances that promote the inflammatory response, and also possesses local anaesthetic activity. Chlorhexidine is an antiseptic agent that kills or prevents the growth of bacteria involved in mouth and throat infections.
Indications
- Tonsillitis
- Sore throat
- Mouth ulcers
- Pain following mouth or throat surgery
- Pain following dental procedures
Therapeutic class
Dental & Oral Preparations
Pharmacological class
Anti-inflammatory + Antiseptic
Pharmacology
Benzydamine is an NSAID that reduces pain and inflammation by reducing the production of hormone-like substances that promote the inflammatory response, and also possesses local anaesthetic activity. Chlorhexidine is an antiseptic agent that kills or prevents the growth of bacteria.
Mechanism of action
Benzydamine reduces pain and inflammation by inhibiting prostaglandin synthesis; Chlorhexidine prevents infection by destroying bacterial cell walls.
Dosage
Adult: Use as a gargle or mouth rinse every 1.5-3 hours as needed. Do not use for more than 7 days. Do not swallow.
Administration
Use as a gargle (for throat conditions) or mouth rinse (for oral lesions). Take a small amount, hold in mouth for 30-60 seconds, then spit out. Do not swallow.
Missed dose
If you miss a dose, use it as soon as possible. However, if it is almost time for your next dose, skip the missed dose.
Side effects
Common (2.6%): Oral numbness.
Rare (<2%): Temporary discolouration of teeth, tongue and dental restorations, burning/stinging sensation, dry mouth/thirst, tingling sensation, warm sensation, taste disturbance, nausea/vomiting, dizziness, headaches/drowsiness, allergic reactions (skin rashes, increased sensitivity to sunlight).
Precautions & warnings
Thoroughly brush teeth before use (to minimize tooth discolouration); do not swallow; do not use for more than 7 days; consult doctor if symptoms do not improve after a few days.
Contraindications
Hypersensitivity to any component.
Drug interactions
No adequate information on drug interactions is available.
Food interactions
Can be used with or without food.
Use in pregnancy
No adequate information is available regarding use during pregnancy. Please consult your doctor.
Pregnancy Category: N/A — always consult a doctor before taking during pregnancy.
Use in lactation
No adequate information is available regarding use during lactation. Please consult your doctor.
Pediatric use
No specific dosage for children; consult your doctor.
Geriatric use
No specific dosage adjustment is necessary for elderly patients.
Renal / hepatic impairment
No special precautions are necessary for patients with kidney or liver problems.
Overdose effects
Excessive use may cause oral irritation or numbness.
Storage conditions
Keep below 30°C temperature, away from light & moisture. Keep out of reach of children.
Chemical structure
Benzydamine + Chlorhexidine gluconate