Generic
Bicarbonate Component [HCO3 Hemodialysis Solution]
6 brands available in the market
At a glance
Bicarbonate Component [HCO3 Hemodialysis Solution] — Haemodialysis solutions. Brands, prices, indication, dosage and side effects available in Bangladesh.
Description
Bicarbonate Component [HCO3 Hemodialysis Solution] belongs to the haemodialysis solutions group. Doctors prescribe it mainly for Bicarbonate Component [HCO3 Hemodialysis Solution] solution is indicated in renal failure, Chronic renal failure and Haemodialysis. Bicarbonate serves a crucial biochemical role in the physiological pH buffering system. Dose, duration and suitability differ from patient to patient, so it should be taken only under a registered physician's advice.
Indications
Bicarbonate Component [HCO3 Hemodialysis Solution] is used in the conditions listed below: • Bicarbonate Component [HCO3 Hemodialysis Solution] solution is indicated in renal failure, Chronic renal failure and Haemodialysis. Bicarbonate serves a crucial biochemical role in the physiological pH buffering system
Therapeutic class
Haemodialysis solutions
Pharmacological class
Active ingredients per unit dose: • Each 1 liter solution contains- • Sodium Chloride: 30.5 gm • Sodium bicarbonate: 66 gm • Highly purified water: q.s. to 1 liter
Mechanism of action
How Bicarbonate Component [HCO3 Hemodialysis Solution] works — key points: • Sodium chloride is the major extracellular cation. • It is important in electrolyte and fluid balance, osmotic pressure control and water distribution as it restores sodium ions. • It is used as a source of electrolytes and water for hydration, treatment of metabolic acidosis, priming solution in haemodialysis and treatment of hyperosmolar diabetes. • It is also used as diluents for infusion of compatible drug additives. • Sodium bicarbonate raises blood and urinary pH by dissociation to provide bicarbonate ions, which neutralises the hydrogen ion concentration. • It also neutralises gastric acid via production of carbon dioxide..
Dosage
Recommended schedule as per the manufacturer's literature: • Acidic component & Bicarbonate Component should be used in the dilution ratio of- • Acidic component: 1.00 Volume • Bicarbonate Component: 1.83 Volume • Purified Water: 34.00 Volume
Precautions & warnings
Points to keep in mind while on Bicarbonate Component [HCO3 Hemodialysis Solution]: • • Bicarbonate Component needs to be used with Acidic component (not to be used alone). • Before use, the mixed solution must be diluted with • highly purified water. • Close the container tightly immediately after use. • Discard solution in case of visible solid particles inside. • Discard solution after 96 hours of first opening..
Contraindications
Avoid Bicarbonate Component [HCO3 Hemodialysis Solution] in the following situations: • Known hypersensitivity to any of the ingredients of this preparation
Drug interactions
Watch for these combinations: • Sodium bicarbonate: Increases toxicity of amphetamines, ephedrine, pseudoephedrine, flecainide, quinidine and quinine. Decreases effects of lithium, chlorpropamide and salicylates due to increased clearance. May affect the absorption of certain drugs due to raised intra-gastric pH. Sodium chloride: May affect serum concentrations of lithium
Storage conditions
Storage: • Keep out of reach of children. Not for Injection. Store below 30°C.