Generic
Boswellia Serrata + Boron
1 brands available in the market
At a glance
Boswellia Serrata + Boron is a combination tablet used for superior support for aging joints, osteoarthritis, and joint discomfort. It contains Undenatured Type II collagen, Glucosamine sulfate, Boswellia serrata, and Boron which support joint comfort and ease of motion.
Description
Boswellia Serrata + Boron is a multi-nutrient formula used for aging joints, osteoarthritis, and joint pain and inflammation. Each tablet contains: Undenatured Type II collagen 20 mg, Glucosamine sulfate 750 mg, Boswellia serrata 50 mg, and Boron (Calcium fructoborate) 0.75 mg.
Undenatured Type II collagen is derived from chicken sternum cartilage using a patented low-temperature, non-enzymatic manufacturing process that preserves the natural triple helix molecular configuration and biological activity. Boswellia serrata promotes joint health by inhibiting inflammatory factors such as the 5-lipoxygenase (5-LOX) enzyme and leukotriene B4. Boron (Calcium fructoborate) contributes to bone health by controlling inflammation associated with loss of bone mineral density.
Indications
- Superior support for aging joints
- Osteoarthritis
- Joint pain and inflammation reduction
- Joint comfort and ease of motion
- Cartilage repair and protection
Therapeutic class
Specific mineral & vitamin combined preparations
Pharmacological class
Joint Health Supplement
Pharmacology
Undenatured Type II collagen is a nutritional supplement derived from chicken sternum cartilage using a patented low-temperature, non-enzymatic manufacturing process that preserves the natural triple helix molecular configuration and biological activity. It contains active binding sites called epitopes which trigger oral tolerization. Glucosamine sulfate is a normal constituent of glycosaminoglycans in cartilage matrix and synovial fluid. Boswellia serrata inhibits 5-LOX enzyme and leukotriene B4 to reduce inflammation. Boron (Calcium fructoborate) is a patented complex that reduces C-reactive protein and supports bone health.
Mechanism of action
- Undenatured Type II collagen: Interacts with Peyer's patches in the small intestine, transforming T-cells into T regulatory cells, which migrate to joint areas and secrete anti-inflammatory cytokines (TGF-β and IL-10), reducing joint inflammation and promoting cartilage repair.
- Glucosamine sulfate: Helps build cartilage and prevents joint structure changes in osteoarthritis with significant symptom improvement.
- Boswellia serrata: Inhibits 5-LOX enzyme, reducing inflammatory leukotriene production and helping prevent cartilage damage.
- Boron (Calcium fructoborate): Reduces CRP and controls inflammation associated with bone mineral density loss, supporting bone health.
Dosage
Adults: 1 tablet orally twice daily after meals or as directed by the physician.
Children & adolescents below 12 years: Safety and effectiveness have not been established.
Administration
Take with adequate water after meals. Swallow the tablet whole; do not chew or crush. Follow the dose and duration as advised by your physician.
Missed dose
If you miss a dose, take it as soon as you remember. Skip the missed dose if it is almost time for your next dose. Do not double the dose.
Side effects
- Nausea
- Heartburn
- Diarrhea
- Constipation
- Uncommon: Drowsiness, skin reactions, headache
Glucosamine sulfate seems to be safe for most people. Some glucosamine products may not contain the labeled amount or may contain excessive amounts of Manganese.
Precautions & warnings
- Diabetic patients should monitor blood glucose levels regularly (glucosamine may increase insulin resistance).
- Patients allergic to shellfish should consult their physician before use (glucosamine is extracted from chitin, a carbohydrate; shellfish allergies are usually caused by protein).
- Use under medical supervision in patients with severe renal or hepatic insufficiency.
- Not recommended during pregnancy and lactation.
Contraindications
- Diabetic patients should use under close medical supervision (glucosamine may increase insulin resistance).
- Patients allergic to shellfish should consult their physician.
- Children, pregnant and nursing women should avoid use (insufficient research available).
Drug interactions
- Blood thinners (warfarin, heparin): Potential interaction with Glucosamine sulfate and Boswellia serrata.
- No other significant drug interactions reported.
Food interactions
No specific food restrictions.
Use in pregnancy
Not recommended during pregnancy (insufficient research available).
Use in lactation
Not recommended during lactation (insufficient research available).
Pediatric use
Safety and effectiveness in children below 12 years have not been established.
Geriatric use
No specific dose adjustment required for elderly, but consult your physician.
Renal / hepatic impairment
Use under medical supervision in patients with severe renal or hepatic insufficiency.
Overdose effects
Signs and symptoms of overdose include nausea, vomiting, diarrhea, constipation, and abdominal discomfort. Consult your doctor if overdose is suspected.
Storage conditions
Store below 30°C in a dry place, protected from light. Keep out of reach of children.
Chemical structure
Undenatured Type II collagen 20 mg + Glucosamine sulfate 750 mg + Boswellia serrata 50 mg + Boron (Calcium fructoborate) 0.75 mg