Generic
Brammiroshayan
2 brands available in the market
At a glance
Brammiroshayan is an Ayurvedic syrup formulated with Brahmi (Bacopa monnieri) along with multiple medicinal herbs. It helps improve memory, attention, and cognitive function.
Description
Brammiroshayan is an Ayurvedic syrup that has been used since ancient times. Its main ingredient is Brahmi (Bacopa monnieri), which is well-known as a nervine tonic. It also contains Shatavari (Asparagus racemosus), Vidari (Ipomoea paniculata), Haritaki (Terminalia chebula), Vena (Vetiveria zizanioides), Ginger (Zingiber officinale), and Fennel (Foeniculum vulgare).
The triterpenoid saponins and bacosides present in Brahmi enhance nerve impulse transmission. Bacosides help repair damaged neurons by enhancing kinase activity, neuronal synthesis, restoring synaptic activity, and modulating cholinergic and GABAergic neurotransmission. It exhibits antioxidant activity in the hippocampus, frontal cortex, and striatum and modulates the expression of enzymes involved in reactive oxygen species regulation in the brain.
Shatavari is a well-known nervine tonic that reduces free radical-induced oxidative neural damage. Its antioxidant compound racemofuran enhances glutathione peroxidase activity and glutathione content while reducing lipid peroxidation and protein carbonyl levels.
This syrup is beneficial for cognitive deficit, age-associated memory impairment, attention deficit disorder, dementia, convulsions and epilepsy in children, Alzheimer's disease, autistic spectrum disorder, and drug addiction.
Indications
- Cognitive deficit
- Age Associated Memory Impairment (AAMI)
- Attention Deficit Disorder (ADD)
- Dementia
- Convulsion and Epilepsy in children
- Alzheimer's disease
- Autistic Spectrum Disorder (ASD)
- Drug addiction
Therapeutic class
Herbal and Nutraceuticals
Pharmacological class
Ayurvedic Herbal Formulation (Brahmi-based)
Pharmacology
Brammiroshayan's main ingredient is Brahmi (Bacopa monnieri), which belongs to the Scrophulariaceae family. It has been used in Ayurvedic medicine for centuries. The compounds responsible for its pharmacological effects include alkaloids, saponins, and sterols. Other active constituents include betulic acid, stigmasterol, beta-sitosterol, and numerous bacosides.
The triterpenoid saponins and bacosides enhance nerve impulse transmission. Bacosides aid in repairing damaged neurons by enhancing kinase activity, neuronal synthesis, restoring synaptic activity, and modulating cholinergic and GABAergic neurotransmission.
Asparagus racemosus is a well-known nervine tonic that attenuates free radical-induced oxidative neural damage. Its antioxidant compound racemofuran enhances glutathione peroxidase activity and glutathione content while reducing membrane lipid peroxidation and protein carbonyl levels.
Mechanism of action
Brammiroshayan's triterpenoid saponins and bacosides enhance nerve impulse transmission. Bacosides repair damaged neurons by enhancing kinase activity and restoring synaptic activity. Brahmi acts as an antioxidant in the hippocampus, frontal cortex, and striatum, regulating enzymes involved in reactive oxygen species management. Shatavari enhances glutathione peroxidase activity and glutathione content while reducing lipid peroxidation and protein carbonyl levels, protecting neurons from oxidative damage.
Dosage
Dosage and Administration:
- 2-5 years: 1 teaspoonful (5 ml) 2-3 times daily after meals for 3 months
- 6-12 years: 1-2 teaspoonfuls (5-10 ml) 2-3 times daily after meals for 3 months
- Above 12 years and Adults: 2-3 teaspoonfuls (10-15 ml) 3 times daily after meals for 3 months
Dosage and duration should be determined as per physician's advice.
Administration
Take the prescribed dose after meals. Shake the bottle well before use. May be mixed with water if needed.
Missed dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
Side effects
No side effects are associated with the use of Bacopa at the therapeutic doses mentioned above. Bacopa has been used safely as an Ayurvedic medicine for hundreds of years. Rarely, mild stomach discomfort may occur in sensitive individuals.
Precautions & warnings
- Caution in hyperthyroidism, fever, and acute infections
- Pregnant and lactating women should consult a doctor before use
- Patients with medical conditions should consult their doctor before use
- Keep out of reach of children
Contraindications
- Hypersensitivity to any component of Brammiroshayan
- Hyperthyroidism (caution)
- Acute infections and fever (caution)
Drug interactions
- Thyroid stimulating drugs: Bacopa may potentiate the activity of thyroid stimulating drugs
- Anti-thyroid medications: Bacopa may decrease the effects of anti-thyroid medications
- Morphine and other opiates: Bacopa may decrease the toxicity of morphine and other opiate drugs
- Phenytoin (anti-seizure medication): Bacopa may reduce the decline in cognitive function associated with phenytoin
Food interactions
Best taken after meals. Can be mixed with milk or water.
Use in pregnancy
[CONSULT YOUR DOCTOR] Limited safety data is available for use during pregnancy. No adverse effects on fetal development have been reported in medical literature, but consultation with a physician is advised.
Use in lactation
[CONSULT YOUR DOCTOR] Limited safety data is available for use during lactation. No adverse effects on breastfed infants have been reported in medical literature, but consultation with a physician is advised.
Pediatric use
- 2-5 years: 1 teaspoonful (5 ml) 2-3 times daily
- 6-12 years: 1-2 teaspoonfuls (5-10 ml) 2-3 times daily
Consult a doctor before use in children under 6 months.
Geriatric use
Adult dosage applies to elderly patients (2-3 teaspoonfuls 3 times daily). Particularly beneficial for dementia and age-related memory decline.
Renal / hepatic impairment
No dose adjustment needed for patients with kidney or liver disease, but consult a doctor before use.
Overdose effects
No cases of overdose have been reported at therapeutic doses. Excessive intake may cause mild stomach discomfort.
Storage conditions
Store in a cool and dry place, away from direct sunlight. Keep out of reach of children.
Chemical structure
Per 5 ml contains: Bacopa monnieri 1.21 g, Asparagus racemosus 0.30 g, Ipomoea paniculata 0.30 g, Terminalia chebula 0.30 g, Vetiveria zizanioides 0.30 g, Zingiber officinale 0.30 g, Foeniculum vulgare 0.30 g