Calcitriol

Calcitriol is the active form of Vitamin D. It increases the levels of Vitamin D in your blood which in turn raises calcium levels in the blood by helping in absorption of more calcium from your intestine. Thus, it is used in the treatment of calcium deficiency and postmenopausal osteoporosis. Calcitriol is given in women after menopause to strengthen weak bones. It helps in reducing the bone damage. It is administered as an injection. It is advised not to self administer the injection, it should be done by a healthcare professional. In case of injection site reactions such as pain, swelling or redness, kindly consult your doctor. Do not take any other form of Vitamin D along with this medicine without consultation of your doctor. Calcium supplements along with Vitamin D3 should only be taken with doctor's advice. Drink plenty of fluids such as water to avoid feeling dehydrated. Avoid using antacids as it can cause difficulty for the medicine to absorb. Inform your doctor if you are pregnant. However, it is safe to use in breastfeeding mothers and liver disease patients. In case of kidney disease patients, dose adjustment is required. Caution is advised when consuming alcohol with Calcitriol. Calcitriol is the active form of Vitamin D. It raises Vitamin D levels in your blood. This in turn raises calcium levels in your blood by helping you absorb more calcium from your intestine.

• Calcium deficiency

Calcitriol promotes calcium absorption in the intestines and retention at the kidneys thus increasing serum calcium levels. It also increases renal tubule phosphate resorption consequently decreasing serum phosphatase levels, PTH levels and bone resorption..

Adult Dose: Adult: Capsule: The optimal daily dose of Calcitriol must be carefully determined for each patient on the basis of the serum calcium level. Calcitriol can be administered orally either 0.25 mcg or 0.50 mcg. Postmenopausal osteoporosis The recommended dosage is 0.25 mcg twice daily or 0.50 mcg once daily. Serum creatinine levels should be determined at 4 weeks, 3 and 6 months and 6 monthly intervals thereafter. Renal osteodystrophy (Dialysis patients) The recommended initial dose of Calcitriol is 0.25 mcg/day. Patients with normal or only slightly reduced serum calcium levels may respond to Calcitriol doses of 0.25 mcg every other day. Most patients undergoing hemodialysis respond to doses between 0.5 and 1 mcg/day. Hypoparathyroidism & Rickets The recommended initial dosage of Calcitriol is 0.25 mcg/day given in the morning. If a satisfactory response is not observed, the dose may be increased at 2 to 4 week intervals. Predialysis patients: The recommended initial dosage of Calcitriol is 0.25 mcg/day in adults. This dosage may be increased if necessary to 0.5 mcg/day. Injection The recommended intravenous initial dose of Calcitriol injection, depending on the severity of the hypocalcemia and/or secondary hyperparathyroidism, is 1 mcg (0.02 mcg/kg) to 2 mcg administered three times weekly, approximately every other day. Doses as small as 0.5 mcg and as large as 4 mcg three times weekly have been used as an initial dose. If a satisfactory response is not observed, the dose may be increased by 0.5 to 1 mcg at two to four week intervals. Child Dose: Chronic Renal Dialysis Associated Hypocalcemia 0.25-2 mcg/day PO qDay Hypoparathyroidism/Pseudohypoparathyroidism 6 years: 0.5-2 mcg PO qDay Familial Hypophosphatemia Initial: 0.015-0.02 mcg/kg PO qDay Maintenance: 0.03-0.06 mcg/kg PO qDay No more than 2 mcg PO qDay Secondary Hyperparathyroidism in Moderate to Severe Kidney Disease 3 years: 0.25 mcg/day PO; may increase to 0.5 mcg/day Hypocalcemia in Premature Infants 1 mcg qDay PO for 5 days

Your doctor or nurse will give you this medicine. Kindly do not self administer.

Common: • Injection site reactions (pain, swelling, redness)

[SAFE] Calcitriol does not usually affect your ability to drive. Do not take any other forms of Vitamin D unless your doctor suggests. Take calcium supplements along with Vitamin D3 as suggested by your doctor. Drink plenty of fluids (such as water) as it is important not to become dehydrated. Avoid using antacids without your doctor's advice. Some antacids can make it harder for your body to absorb calcitriol. Consult your doctor if you notice a metallic taste in mouth, muscle or joint pain, headache or drowziness.

Hypercalcaemia; evidence of vitamin D toxicity. Pregnancy (dose exceeding RDA). Lactation.

Hypermagnesaemia may develop in patients on chronic renal dialysis. Hypercalcaemia in patients on digitalis may precipitate cardiac arrhythmias. Intestinal absorption of calcitriol may be reduced by cholestyramine and colestipol. Phenytoin, barbiturates may decrease the T1/2 of calcitriol. May develop hypercalcaemia with thiazide diuretics.

[CAUTION] Caution is advised when consuming alcohol with Calcitriol. Please consult your doctor.

[CONSULT YOUR DOCTOR] Calcitriol may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

[SAFE IF PRESCRIBED] Calcitriol is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.

[CAUTION] Calcitriol should be used with caution in patients with severe kidney disease. Dose adjustment of Calcitriol may be needed. Please consult your doctor. However, regular monitoring of phosphate levels may be advised while you are taking this medicine. [SAFE IF PRESCRIBED] Calcitriol is safe to use in patients with liver disease. No dose adjustment of Calcitriol is recommended.

Vitamin D deficiency in body. Please suggest some food or medicine. Calcirol sachet weekly for three months What medicine to take for deficiency of vitamin D3? Calcirol sachet and the natural way is to tale morning sunrays Mild pain in calf muscles of both legs since Feb 16. Test results sugar 116, vit d vit b12 thyroid normal uric acid 5.7 For vit D deficiency Calcirol sachet 60K units weekly for three months I have deficiency of vitamin D (17)and vitamin B12(156) in my blood test report. Calcirol sachet weekly for 3 monthsTab Matilda forte OD for 3months Diagnosis:: endometriosis Medicine:: endoreg Age::38 Apart from this what to do for healthy life. Don't want pregnancy Other medicine:: thyrox.5mg,corcium,autrim,telma40,fol g1, calcirol gems,caberlin.5 Keep your thyroid and prolactin levels checked regularly. Use a reliable method of protection to avoid pregnancy.check your BP regularly. Continue iron and calcium supplements. Eat a balanced diet.exercise regularly. High TSH and low B12 and vitamin D. Actually there is a deficiency of vitamin D and B12 in a way Tab neurobion forte ODCalcirol sachet 60K units weekly for three months