Generic
Carica Papaya Leaf Extract
5 brands available in the market
At a glance
Carica Papaya Leaf Extract is a herbal supplement used in the treatment of thrombocytopenia (low platelet count) associated with dengue and chemotherapy-induced thrombocytopenia. It also improves digestion, boosts immunity, enhances skin health, and relieves menstrual pain.
Description
Carica papaya, belonging to the plant family Caricaceae, is an economically important fruit crop worldwide. Many scientific works have been carried out to evaluate the benefit of different parts of the papaya plant including fruits, seeds, leaves, rind, shoots, roots, or latex. The leaf is considered non-toxic as its lethal dose is >15 g/kg body weight.
Carica Papaya Leaf Extract is indicated for thrombocytopenia associated with dengue and chemotherapy-induced thrombocytopenia. It also increases the taste of food, aids in digestion, eliminates constipation, reduces inflammation of the stomach and colon, keeps the liver clean, boosts immunity, removes acne, ensures healthy and beautiful skin, and relieves menstrual pain.
Indications
- Thrombocytopenia associated with dengue
- Chemotherapy-induced thrombocytopenia
- Increases taste of food
- Aids in digestion
- Eliminates constipation
- Reduces inflammation of stomach and colon
- Keeps the liver clean
- Boosts immunity
- Removes acne
- Ensures healthy and beautiful skin
- Relieves menstrual pain
Therapeutic class
Herbal and Nutraceuticals
Pharmacological class
Herbal Supplement (Papaya Leaf Extract)
Pharmacology
Carica Papaya Leaf Extract is a natural supplement that helps increase platelet count. In natural medicine, papaya leaf extract is a popular home remedy for dengue patients to boost blood platelets. Recent in vitro studies have shown that papaya leaf extract significantly inhibits hemolysis, probably due to its membrane-stabilizing potency.
Mechanism of action
Carica Papaya Leaf Extract stimulates megakaryocyte production in the bone marrow and stabilizes platelet membranes to increase platelet count. Its antioxidant components protect cells from oxidative stress and strengthen the immune system.
Dosage
Adults: 250 mg 1-2 capsules daily 2-3 times a day for 5-12 days, or as directed by a physician.
Children 1-5 years: 1 teaspoonful (5 ml) three times a day for 5 days.
Children 5-18 years: 2 teaspoonful (10 ml) three times a day for 5 days.
18 years and above: 3 teaspoonful (15 ml) three times a day for 5 days, or as directed by a physician.
Note: Do not use long-term without medical advice.
Administration
Take as advised by your physician, with or without food. Swallow capsules whole; do not chew or crush. Shake the syrup bottle well before use.
Missed dose
If you miss a dose, take it as soon as you remember. Skip the missed dose if it is almost time for your next dose. Do not double the dose.
Side effects
No health hazards or side effects are known with proper administration of designated therapeutic dosages. Rarely, allergic reactions may occur.
Precautions & warnings
- Use with caution in individuals with bleeding disorders or those taking blood thinning medications such as aspirin or warfarin.
- Co-administration with oral hypoglycemic agents may lead to very low blood glucose; monitor blood glucose levels regularly.
- Not recommended during pregnancy and lactation.
- Avoid in males with prostate dysfunction (BPH or prostate cancer) as it increases iron absorption.
Contraindications
- Hypersensitivity
- Pregnancy
- Prostate dysfunction in males (BPH or prostate cancer) - increases iron absorption which may increase oxidative stress
Drug interactions
- Amiodarone: May increase bioavailability; dose adjustment required.
- Antibiotics (penicillin G, ampicillin, amoxyclav, cephalothin, polymyxin B, rifampicin, amikacin, nalidixic acid, gentamycin, chloramphenicol, ofloxacin): Co-administration may potentiate antimicrobial action (synergistic effect).
Food interactions
No specific food restrictions.
Use in pregnancy
Not recommended during pregnancy.
Use in lactation
Not recommended during lactation.
Pediatric use
Children: 1-5 years: 5 ml three times daily for 5 days; 5-18 years: 10 ml three times daily for 5 days.
Geriatric use
No specific dose adjustment required for elderly, but consult your physician.
Renal / hepatic impairment
No special precautions required for patients with liver or kidney impairment, but consult your physician.
Overdose effects
Overdose may cause stomach discomfort. Consult your doctor if overdose is suspected.
Storage conditions
Keep away from direct sunlight and moisture. Store below 30°C in a cool and dry place. Keep out of reach of children.
Chemical structure
Carica papaya (Papaya) Leaf Extract