Ceftriaxone

Ceftriaxone is an antibiotic belonging to the cephalosporin group, which is used to treat bacterial infections in your body. It is effective in infections of the brain (e.g., meningitis), lungs (e.g., pneumonia), ear, urinary tract, skin & soft tissues, bones & joints, blood and heart. Ceftriaxone is also used to prevent infections during surgery. It fights the infection by killing the bacteria. This helps to improve your symptoms and cure the underlying infection. It is given as a drip (intravenous infusion) or as an injection directly into a vein or a muscle under the supervision of a healthcare professional. Your doctor will decide the correct dose for you. This medicine will be given to you regularly at evenly spaced intervals as per the schedule prescribed by your doctor. Do not skip any doses and finish the full course of treatment even if you feel better. Stopping the medicine too early may lead to the returning or worsening of infection. The most common side effects of this medicine include diarrhea, rash, and changes in liver function tests and blood cell counts. Some people may develop temporary redness or pain at the site of injection. These side effects are usually mild but let your doctor know if they bother you or do not go away. Before taking it, you should let your doctor know if you are allergic to any antibiotics or have any kidney or liver problems. You should also let your healthcare team know all other medicines you are taking as they may affect, or be affected by this medicine. Pregnant and breastfeeding women should consult their doctor before using it. Ceftriaxone is an antibiotic. It kills the bacteria by preventing them from forming the bacterial protective covering (cell wall) which is needed for them to survive.

• Bacterial infections

Ceftriaxone binds to one or more of the penicillin-binding proteins (PBPs) which inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell wall, thus inhibiting biosynthesis and arresting cell wall assembly resulting in bacterial cell death.

Adult Dose: Susceptible infections IV/IM 1-2 g/day, up to 4 g/day for severe infections. Intra-abdominal Infections Complicated, mild-to-moderate, community acquired: 1-2 g/day IV in single daily dose or divided q12hr for 4-7 days, in combination with metronidazole Meningitis 2 g IV q12hr for 7-14 days Acute Uncomplicated Pyelonephritis 1-2 g IV qDay Typhoid fever 2 g IV once daily for 14 days. Surgical Prophylaxis Prophylaxis of surgical infection 1 g IV 0.5-2 hours before procedure Uncomplicated Gonococcal Infections Uncomplicated gonococcal infection of pharynx, cervix, urethra, or rectum: ceftriaxone 250 mg IM once plus azithromycin 1 g PO once (preferred) or alternatively, doxycycline 100 mg PO q12hr for 7 days Pelvic Inflammatory Disease 250 mg IM as single dose with doxycycline, with or without metonidazole for 14 days Child Dose: Children: IV, IM: 50–75 mg/kg/day, max 2 g/day q24h 50 mg/kg, max 1 g, 1–3 doses IM for AOM q24h 100 mg/kg/day for meningitis, max 4 g/day q12h Renal Dose: Renal impairment: CrCl (ml/min) <10 Max: 2 g daily.

Your doctor or nurse will give you this medicine. Kindly do not self administer.

If you miss a dose of Ceftriaxone, please consult your doctor.

Common: • Abnormal liver function tests • Diarrhea • Rash

[UNSAFE] Ceftriaxone may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur. Your doctor has prescribed Ceftriaxone to cure your infection and improve your symptoms. Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early may make the infection harder to treat. Discontinue Ceftriaxone and inform your doctor immediately if you get a rash, itchy skin, swelling of face and mouth, or have difficulty in breathing. Diarrhea may occur as a side effect but should stop when your course is complete. Inform your doctor if it does not stop or if you find blood in your stools.

Hypersensitivity to cephalosporins; hyperbilirubinaemic neonates. Do not use calcium or calcium-containing solutions or products with or within 48 hr of ceftriaxone administration due to risk of calcium-ceftriaxone precipitate formation.

May increase nephrotoxicity of aminoglycosides. May diminish therapeutic effect of BCG, typhoid vaccine, Na picosulfate. May increase anticoagulant effect of vit K antagonists (e.g. warfarin). May increase serum level w/ probenecid. Potentially Fatal: Admin w/ Ca-containing IV soln may cause precipitation of a crystalline material in the lungs and kidneys.

[SAFE] Consuming alcohol with Ceftriaxone does not cause any harmful side effects.

[SAFE IF PRESCRIBED] Ceftriaxone is safe to use during pregnancy. Most studies have shown low or no risk to the developing baby.

[CAUTION] Ceftriaxone should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.

[SAFE IF PRESCRIBED] Ceftriaxone is safe to use in patients with kidney disease. No dose adjustment of Ceftriaxone is recommended. However, inform your doctor if you have any underlying kidney disease. [CAUTION] Ceftriaxone should be used with caution in patients with severe liver disease. Dose adjustment of Ceftriaxone may be needed. Please consult your doctor. Dose adjustment of Ceftriaxone is not recommended in patients with mild to moderate liver disease.

Loose motions with weakness. Took some medicine and it&#x27;s better now but the pain and motion haven&#x27;t stopped completely. Stomach feels heavy and gas is continuously being formed which is leading to motions.Have consulted with a doctor yesterday and he prescribed - Andial, Redotil and Monocef-o-200, Nexpro RD. stop MONOCEF O , rest continue Monocef o 50 syrup in safe in cough khasi Please consult Dr. will take detail history and will examine your child in detail. may ask you for blood test. All information will be used to determine exact underlying cause of problem. Depending upon cause will prescribe you treatment. Khasi ho gai h 4 days se monocef 50 diya tha There are many underlying causes of Patient?s symptoms. Different cause needs different treatment. Specific treatment cannot be given unless we establish exact underlying cause. Final and perfect diagnosis cannot be done without doing clinical examination of patient. Please consult me or any other Paediatrician. will take detail history and will examine patient in detail. All information will be used to determine exact underlying cause of problem. Depending upon cause will prescribe you treatment. At time may ask you relevant investigations if necessary.Patient may need antibiotics and/or other prescription drugs. It is mandatory for the customer to have a prescription for the prescription medicines he/she is procuring. Valid prescription cannot be given without diagnosis. During pregnancy patient for fever monocef antibiotic are suggestible or not?? Yes can be given Cold cough then ear block feelings take monocef & leoped for 10days no improvment can be sinusitis with ear drum infection visit ent specialist near you for proper examination Going to high altitude place for vacation PATIENT allergic to MONOCEF . can he take Diamox 250 mg if need be? If you are asking about cross reactivity between MONOCEF and DIAMOX, they are entirely different medicines with different mechanism of action and there should not be any cross reactivity. more pain in both hand and both foots joint. since 18 days and i have taken paracitamaol,aclofeneac cefafroxil shellcall etc. and two times take injection of MONOCEF. AMIKACIN M.V.I. Please get your vitamin d 3 checked as this is the most common cause of your symptoms Scar on face due to bacterial infections Pic is not clear, plz visit for proper opinion