Generic
Chlorhexidine Gluconate 1% Oral prep
2 brands available in the market
At a glance
Chlorhexidine Gluconate 1% Oral prep is an antiseptic used for the treatment of gum inflammation (gingivitis) and mouth infections.
Description
Chlorhexidine Gluconate 1% Oral prep is used in the treatment of inflammation of gums. It works by killing harmful microorganisms in the oral cavity. Use it as directed by the dentist. Chlorhexidine Gluconate 1% Oral prep is an antiseptic that binds strongly to the surface of teeth, inner cheeks and gums. It works by killing the harmful microorganisms that cause swollen gums, tartar, bad odour from mouth, and other mouth infections. Chlorhexidine is a very potent cationic chemoprophylactic agent that has a broad-spectrum of activity against gm+ve and gm-ve bacteria.
Indications
- Gingivitis (Gum inflammation)
- Mouth infections
- Bad breath (Halitosis)
- Tartar (Dental calculus)
- Swollen gums
Therapeutic class
Other antibacterial preparation
Pharmacological class
Antiseptic (Oral Gel/Cream)
Pharmacology
Chlorhexidine is a very potent cationic chemoprophylactic agent that has a broad-spectrum of activity against gm+ve and gm-ve bacteria. It is both bacteriostatic and bactericidal depending on its concentration. The bactericidal effect, which is achieved at high concentrations, is due to the binding of the cationic to negatively charged bacterial cell walls and extramicrobial complexes. Bacteriostatic effect is achieved at low concentrations which causes an alteration of bacterial cell osmotic equilibrium and leakage of potassium and phosphorus.
Mechanism of action
Chlorhexidine, as a positively charged cation, binds to negatively charged bacterial cell walls. At high concentrations it destroys the bacterial cell wall, and at low concentrations it alters osmotic equilibrium and inhibits bacterial growth.
Dosage
Adult Dose: Apply to the affected area 2-3 times daily or as directed by the physician.
Administration
Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use.
Missed dose
If you miss a dose of Chlorhexidine Gluconate 1% Oral prep, please consult your doctor.
Side effects
Common Side Effects:
- Taste change
- Staining of teeth
- Hard Dental Plaque
- Tongue discoloration
Serious Side Effects (Rare): Allergic reactions (sudden wheeziness, swelling of eyelids/face/lips, rash or itching).
Precautions & warnings
- Use after meals, it may affect the taste of foods and beverages.
- For maximum effectiveness avoid rinsing mouth (with water or any other mouthwash), brushing teeth, eating or drinking for 30 minutes after use.
- May cause permanent discolouration of some tooth fillings. To minimize discolouration, brush and floss daily.
- Do not mix/dilute with any other product.
- Avoid contact with eyes and ears.
Contraindications
- Hypersensitivity to Chlorhexidine or any of the excipients in the formulation.
Drug interactions
Incompatible with soaps, other anionic agents, borates, bicarbonates, carbonates, chlorides, citrates, nitrates, phosphates & sulfates.
Food interactions
No food interactions have been found or established. However, it may affect the taste of food.
Use in pregnancy
[CONSULT YOUR DOCTOR] Chlorhexidine Gluconate 1% Oral prep may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Use in lactation
[SAFE IF PRESCRIBED] Chlorhexidine Gluconate 1% Oral prep is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Pediatric use
Limited information is available regarding use in children. Use as advised by a physician.
Geriatric use
Limited information is available regarding dose adjustment for elderly patients.
Renal / hepatic impairment
No information is available on use in kidney or liver problems.
Overdose effects
Information on overdosage is not available. Consult a physician if overdose is suspected.
Storage conditions
Keep in a cool and dry place protected from light. Keep out of reach of children.
Chemical structure
Chlorhexidine Gluconate 1%