Generic
Chlorhexidine Gluconate 1% Vag Prep
1 brands available in the market
At a glance
Chlorhexidine Gluconate 1% Vag Prep is an antiseptic used for vaginal and skin disinfection.
Description
Chlorhexidine Gluconate 1% Vag Prep is an antiseptic cream/solution used for skin and vaginal disinfection. It is used by healthcare professionals as an antiseptic cream and lubricant when examining women during pregnancy or for gynecological problems. Chlorhexidine is a very potent cationic chemoprophylactic agent that has a broad-spectrum of activity against gm+ve and gm-ve bacteria. It is both bacteriostatic and bactericidal depending on its concentration.
Indications
- Vaginal and skin disinfection
- Antiseptic and lubricant for gynecological examinations
- Antiseptic during pregnancy examinations
Therapeutic class
Other antibacterial preparation
Pharmacological class
Antiseptic (Vaginal/Skin Cream)
Pharmacology
Chlorhexidine is a very potent cationic chemoprophylactic agent that has a broad-spectrum of activity against gm+ve and gm-ve bacteria. It is both bacteriostatic and bactericidal depending on its concentration. The bactericidal effect, which is achieved at high concentrations, is due to the binding of the cationic to negatively charged bacterial cell walls and extramicrobial complexes. Bacteriostatic effect is achieved at low concentrations which causes an alteration of bacterial cell osmotic equilibrium and leakage of potassium and phosphorus.
Mechanism of action
Chlorhexidine, as a positively charged cation, binds to negatively charged bacterial cell walls. At high concentrations it destroys the bacterial cell wall, and at low concentrations it alters osmotic equilibrium and inhibits bacterial growth.
Dosage
Adult Dose: Apply to skin or affected area as cream or solution. Used by healthcare professionals during examination by applying on gloved hand and around birth canal and perineum.
Administration
Check the label before use. Take the quantity as advised by your doctor and apply. For use on skin or vagina only.
Missed dose
If you miss a dose of Chlorhexidine Gluconate 1% Vag Prep, please consult your doctor.
Side effects
Common Side Effects:
- Skin irritation
- Allergic reactions
Serious Side Effects (Rare): Allergic reactions (sudden wheeziness, swelling of eyelids/face/lips, rash or itching).
Precautions & warnings
- Avoid application to ears and eyes. Wash out with water if necessary.
- If mixed with soap or detergents its effectiveness may reduce.
- Avoid application to deep cuts involving the head or spine.
- For use on skin or vagina only.
Contraindications
- Hypersensitivity to Chlorhexidine.
Drug interactions
Chlorhexidine is incompatible with soaps and other anionic agents. Hypochlorite bleaches may cause brown stains to develop in fabrics which have previously been in contact with preparations containing Chlorhexidine.
Food interactions
No food interactions have been found or established.
Use in pregnancy
Chlorhexidine Gluconate 1% Vag Prep is safe during pregnancy. There is no evidence of any adverse effects on the fetus.
Use in lactation
Chlorhexidine Gluconate 1% Vag Prep is safe during lactation. There is no evidence of any adverse effects on the infant.
Pediatric use
Limited information is available regarding use in children. Use as advised by a physician.
Geriatric use
Limited information is available regarding dose adjustment for elderly patients.
Renal / hepatic impairment
No information is available on use in kidney or liver problems.
Overdose effects
Information on overdosage is not available. Consult a physician if overdose is suspected.
Storage conditions
Keep in a cool and dry place protected from light. Shake the bottle well before use. Keep out of reach of children.
Chemical structure
Chlorhexidine Gluconate 1%