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Chlorhexidine Gluconate 1% Vag Prep

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At a glance

Chlorhexidine Gluconate 1% Vag Prep is an antiseptic used for vaginal and skin disinfection.

Description

Chlorhexidine Gluconate 1% Vag Prep is an antiseptic cream/solution used for skin and vaginal disinfection. It is used by healthcare professionals as an antiseptic cream and lubricant when examining women during pregnancy or for gynecological problems. Chlorhexidine is a very potent cationic chemoprophylactic agent that has a broad-spectrum of activity against gm+ve and gm-ve bacteria. It is both bacteriostatic and bactericidal depending on its concentration.

Indications
  • Vaginal and skin disinfection
  • Antiseptic and lubricant for gynecological examinations
  • Antiseptic during pregnancy examinations
Therapeutic class

Other antibacterial preparation

Pharmacological class

Antiseptic (Vaginal/Skin Cream)

Pharmacology

Chlorhexidine is a very potent cationic chemoprophylactic agent that has a broad-spectrum of activity against gm+ve and gm-ve bacteria. It is both bacteriostatic and bactericidal depending on its concentration. The bactericidal effect, which is achieved at high concentrations, is due to the binding of the cationic to negatively charged bacterial cell walls and extramicrobial complexes. Bacteriostatic effect is achieved at low concentrations which causes an alteration of bacterial cell osmotic equilibrium and leakage of potassium and phosphorus.

Mechanism of action

Chlorhexidine, as a positively charged cation, binds to negatively charged bacterial cell walls. At high concentrations it destroys the bacterial cell wall, and at low concentrations it alters osmotic equilibrium and inhibits bacterial growth.

Dosage

Adult Dose: Apply to skin or affected area as cream or solution. Used by healthcare professionals during examination by applying on gloved hand and around birth canal and perineum.

Administration

Check the label before use. Take the quantity as advised by your doctor and apply. For use on skin or vagina only.

Missed dose

If you miss a dose of Chlorhexidine Gluconate 1% Vag Prep, please consult your doctor.

Side effects

Common Side Effects:

  • Skin irritation
  • Allergic reactions

Serious Side Effects (Rare): Allergic reactions (sudden wheeziness, swelling of eyelids/face/lips, rash or itching).

Precautions & warnings
  • Avoid application to ears and eyes. Wash out with water if necessary.
  • If mixed with soap or detergents its effectiveness may reduce.
  • Avoid application to deep cuts involving the head or spine.
  • For use on skin or vagina only.
Contraindications
  • Hypersensitivity to Chlorhexidine.
Drug interactions

Chlorhexidine is incompatible with soaps and other anionic agents. Hypochlorite bleaches may cause brown stains to develop in fabrics which have previously been in contact with preparations containing Chlorhexidine.

Food interactions

No food interactions have been found or established.

Use in pregnancy

Chlorhexidine Gluconate 1% Vag Prep is safe during pregnancy. There is no evidence of any adverse effects on the fetus.

Use in lactation

Chlorhexidine Gluconate 1% Vag Prep is safe during lactation. There is no evidence of any adverse effects on the infant.

Pediatric use

Limited information is available regarding use in children. Use as advised by a physician.

Geriatric use

Limited information is available regarding dose adjustment for elderly patients.

Renal / hepatic impairment

No information is available on use in kidney or liver problems.

Overdose effects

Information on overdosage is not available. Consult a physician if overdose is suspected.

Storage conditions

Keep in a cool and dry place protected from light. Shake the bottle well before use. Keep out of reach of children.

Chemical structure

Chlorhexidine Gluconate 1%

Common questions

What is Chlorhexidine Gluconate 1% Vag Prep used for?
It is used for vaginal and skin disinfection and as an antiseptic lubricant for gynecological examinations.
How to use Chlorhexidine Gluconate 1% Vag Prep?
Apply to the skin or vagina as advised by your doctor. For external use only.
What are the side effects of Chlorhexidine Gluconate 1% Vag Prep?
Skin irritation and allergic reactions.
Can Chlorhexidine Gluconate 1% Vag Prep be used during pregnancy?
Yes, it is safe during pregnancy.
Where should Chlorhexidine Gluconate 1% Vag Prep not be used?
Do not use on eyes, ears, deep cuts, or wounds involving the head or spine.
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.