Chondroitin + Glucosamine

Chondroitin + Glucosamine is a combination of two medicines. It is used in the treatment of osteoarthritis. It reduces pain and swelling by reducing inflammation. It also reduces friction in the joints and makes physical movements more comfortable and pain free. Chondroitin + Glucosamine may be prescribed alone or in combination with another medicine. It can be taken with or without food. Take it regularly and do not take more or use it for a longer duration than recommended by your doctor. You should not stop taking the medicine until your doctor tells you it is okay to stop. Using this medicine may cause a few common side effects such as nausea, diarrhea, constipation, and heartburn.

Chondroitin + Glucosamine is a combination of two medicines: Glucosamine and Chondroitin, which relieves osteoarthritis symptoms. It helps in the formation of cartilage (the soft tissue that cushions the joints) and keep the joints lubricated for better movement and flexibility.

• Osteoarthritis (knee, hip, spine, hand, and other locations)
• Rheumatoid arthritis
• Sports injuries
• Migraine
• Skin problems (psoriasis)
• Vascular complications (atherosclerosis)
• Kidney stones
• Inflammatory bowel disease (ulcerative colitis, leaky gut syndrome)

Glucosamine is a natural amino-sugar, produced by the body and found in certain foods. It is the most fundamental building block required for biosynthesis of glycosaminoglycans (GAGs) like Hyaluronic Acid, Keratan Sulfate, and Chondroitin Sulfate. GAGs binds with protein and form proteoglycans, the essential building block of articular cartilage. When cartilage in a joint deteriorates, Osteoarthritis develops.

Chondroitin Sulfate is a glycosaminoglycan (acid muco polysaccharide) found in connective tissue, especially in the articular cartilage of all mammals. Chondroitin Sulfate supplement acts similarly as Glucosamine Sulfate, since it also provide substrate for proteoglycans. Chondroitin also protects existing healthy cartilage from premature decline by preventing the MMP enzyme that breakdowns the proteoglycans.

Glucosamine Sulfate stimulates the production of proteoglycans and increases sulfate uptake by articular cartilage. Chondroitin Sulfate helps maintain cartilage elasticity, repairs cartilage, and reduces synovial inflammation.

Adult Dose (Oral): 1 to 2 tablets three times daily or as directed by the physician.

Weight-based Dosage (per day):

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Chondroitin + Glucosamine may be taken with or without food, but it is better to take it at a fixed time.

If you miss a dose of Chondroitin + Glucosamine, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Common Side Effects:

• Nausea
• Diarrhea
• Constipation
• Heartburn
• Abdominal pain
• Indigestion
• Flatulence (rare)

• Diabetic patients should monitor blood glucose levels regularly.
• Use under medical supervision in patients with severe hepatic or renal insufficiency.
• It may take several weeks to see treatment benefits.
• Inform your doctor if symptoms do not improve after 2-3 months.
• Do not use if allergic to shellfish or sulfur.

• Proven hypersensitivity to Glucosamine or Chondroitin (e.g., allergy to shellfish or sulfur).

May increase insulin resistance & affect glucose tolerance; reduce antidiabetic agent effectiveness. Increase INR value with warfarin & potentiates anticoagulant effect.

[CAUTION] Caution is advised when consuming alcohol with Chondroitin + Glucosamine. Please consult your doctor.

[CONSULT YOUR DOCTOR] Information regarding the use of Chondroitin + Glucosamine during pregnancy is not available. Women who are pregnant or who could become pregnant should not supplement with Glucosamine or Chondroitin.

[SAFE IF PRESCRIBED] Chondroitin + Glucosamine is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby. Should be taken with caution and medical advice during lactation.

Children should not be supplemented with Glucosamine and Chondroitin.

Limited information is available regarding dose adjustment for elderly patients.

[CONSULT YOUR DOCTOR] There is limited information available on the use of Chondroitin + Glucosamine in patients with kidney disease. Please consult your doctor. Patients with severe renal insufficiency should use under appropriate medical supervision.

[CONSULT YOUR DOCTOR] There is limited information available on the use of Chondroitin + Glucosamine in patients with liver disease. Please consult your doctor. Patients with severe hepatic insufficiency should use under appropriate medical supervision.

Information on Chondroitin + Glucosamine overdosage is not available. Consult a physician if overdose is suspected.

Store in a cool and dry place, protected from light. Keep out of reach of children.

Glucosamine + Chondroitin