Clioquinol 1% + Flumetasone Pivalate 0.02% Ear prep

Clioquinol 1% + Flumetasone Pivalate 0.02% Ear prep is a combination medicine used for the treatment of inflammation of the external ear, especially with suspected secondary infection. Flumetasone pivalate is a moderately potent glucocorticoid with anti-inflammatory, anti-allergic, vasoconstrictive and anti-proliferative effects. Clioquinol is a bacteriostatic agent active against a broad spectrum of pathogenic micro-organisms, including fungi and gram-positive bacteria (e.g., staphylococci). It has only a moderate inhibitory effect on gram-negative bacteria.

• Inflammation of the external ear (with suspected secondary infection)

Flumetasone pivalate is a moderately potent glucocorticoid, usually used for local application. It has an anti-inflammatory, anti-allergic, vasoconstrictive and anti-proliferative effect. Clioquinol is a bacteriostatic agent that is active against a broad spectrum of pathogenic micro-organisms, including fungi and gram-positive bacteria (e.g., staphylococci). It has only a moderate inhibitory effect on gram-negative bacteria.

Flumetasone pivalate reduces inflammation and allergy with vasoconstrictive and anti-proliferative effects. Clioquinol inhibits the growth of bacteria and fungi.

Adult Dose (Ear Drops): Inflammation of the external ear with suspected secondary infection: Instill 2-3 drops twice daily directly into the auditory canal of the affected ear. Recommended treatment duration: 7-10 days. Patient should be seated or lying down with the treated ear turned upwards during application. Maintain this position for at least 1-2 minutes after application.

Instill ear drops directly into the auditory canal of the affected ear. Patient should be seated or lying down with the treated ear turned upwards during application. Maintain this position for at least 1-2 minutes after application.

If you miss a dose of Clioquinol 1% + Flumetasone Pivalate 0.02% Ear prep, use it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose. Do not double the dose.

Common Side Effects:

• Irritation at the site of application (burning sensation, itching or skin rash)
• Hair discolouration

Serious Side Effects (Rare): Adrenal suppression (with prolonged use).

• Prolonged use may lead to adrenal suppression.
• Preparation should not come into contact with the conjunctiva.
• Discontinue treatment if there is severe irritation or sensitisation or if there is no improvement after 1 week of application.
• Caution during pregnancy and lactation.
• Do not use in tympanic membrane perforation.
• Do not use in children under 2 years.

• Hypersensitivity to any component of the formulation or iodine
• Primary bacterial, viral or fungal infections of the outer ear
• Tympanic membrane perforation
• Children under 2 years

No significant drug interactions are known.

No food interactions have been found or established.

Limited information is available regarding the use of Clioquinol 1% + Flumetasone Pivalate 0.02% Ear prep during pregnancy. Consult your doctor before use.

Limited information is available regarding the use of Clioquinol 1% + Flumetasone Pivalate 0.02% Ear prep during breastfeeding. Consult your doctor before use.

Not recommended for use in children under 2 years of age.

Limited information is available regarding dose adjustment for elderly patients.

For topical/ear use, no dose adjustment is required in renal or hepatic impairment.

Information on overdosage is not available. Consult a physician if overdose is suspected.

Store in a cool and dry place, away from light and out of reach of children.

Clioquinol + Flumetasone Pivalate