Clobetasol Propionate + Terbinafine Hydrochloride + Ofloxacin + Ornidazole

Clobetasol Propionate + Terbinafine Hydrochloride + Ofloxacin + Ornidazole is a combination cream which exhibits anti-bacterial, anti-fungal, anti-protozoal & anti-inflammatory actions. Ofloxacin is a broad-spectrum antibiotic that acts against many gram-positive & gram-negative bacteria. Ornidazole belongs to the nitroimidazole group of antibiotics and is used to treat amoeba and trichomonas infections. Terbinafine is an Allylamine antifungal that inhibits biosynthesis of Ergosterol (an essential component of fungal cell membrane) via inhibition of Squalene Epoxidase enzyme causing fungal cell death. Clobetasol is a potent corticosteroid which exhibits anti-inflammatory, anti-pruritic and vasoconstrictive properties.

• Mixed and complicated Fungal, Protozoal & Bacterial infections
• Mild to moderate vaginitis
• Candidiasis and trichomoniasis
• Pruritus vulvae
• Dermatitis
• Eczema
• Genito-urinary infections

This cream is a combination cream which exhibits anti-bacterial, anti-fungal, anti-protozoal & anti-inflammatory actions. Ofloxacin is a broad-spectrum antibiotic that acts against many gram-positive & gram-negative bacteria. Ornidazole belongs to the nitroimidazole group of antibiotics and is used to treat amoeba and trichomonas infections. Terbinafine is an Allylamine antifungal that inhibits biosynthesis of Ergosterol (an essential component of fungal cell membrane) via inhibition of Squalene Epoxidase enzyme causing fungal cell death. Clobetasol is a potent corticosteroid which exhibits anti-inflammatory, anti-pruritic and vasoconstrictive properties.

Ofloxacin inhibits bacterial DNA gyrase. Terbinafine inhibits squalene epoxidase, preventing fungal cell wall formation. Ornidazole damages DNA of anaerobic bacteria and protozoa. Clobetasol reduces inflammation and itching by blocking inflammatory mediators.

Adult & Pediatric Dose: Apply by gently rubbing onto the affected area twice daily.

This cream is for external use only. Wash your hands before use. Clean and dry the affected area and apply a small amount of cream. Gently massage into the skin. Wash hands after application (unless hands are the affected area).

If you miss a dose of this cream, apply it as soon as you remember. However, if it is almost time for your next application, skip the missed dose. Do not double the dose.

Common Side Effects:

• Application site irritation
• Itching
• Skin irritation
• Dry skin
• Burning sensation

Serious Side Effects (Rare): Allergic reactions, skin atrophy, striae, telangiectasia (with prolonged use).

• For external use only. Do not swallow.
• Avoid contact with eyes, mouth and nose.
• Avoid prolonged use (may cause skin atrophy).
• Do not use on large areas or with occlusive dressings.
• Consult a doctor before use during pregnancy and lactation.
• Avoid long-term use in children.

• Hypersensitivity to any of the components of the formulation.

No hazardous interactions have been reported.

No food interactions have been found or established.

The safe use of this preparation during pregnancy has not been established. Consult your doctor before use.

The safe use of this preparation during lactation has not been established. Consult your doctor before use.

Avoid long-term use in children. Consult a doctor before use.

Limited information is available regarding dose adjustment for elderly patients.

For topical use, no dose adjustment is required in renal or hepatic impairment.

Information on overdosage is not available. Consult a physician if overdose is suspected.

Store below 30°C. Keep away from light and out of reach of children. Do not freeze.

Ofloxacin + Ornidazole + Terbinafine + Clobetasol