Generic
Curcuminoids
3 brands available in the market
At a glance
Curcuminoids (Curcuma longa) is a herbal supplement used for the treatment of rheumatoid arthritis, osteoarthritis, traumatic swelling and pain, dental plaque, and cancer-associated pain or inflammation.
Description
Curcuminoids is the yellow pigment of Curcuma longa and has long traditional medicinal use in gastric ulcers and dyspepsia. Modern cellular studies on Curcuminoids with almost 4000 pre-clinical investigations, prove it as one of the best studied natural products of the whole biomedical literature. Curcuminoids is known as a master switch of addressing the natural inflammatory response function by down regulating the expression of a series of cytokines, enzymes and transcription factors. Curcuminoids significantly reduces the expression of COX-2, TNF-α, IL-1β, IL-1RN and IL-6. It inhibits the formation of prostaglandin. Curcuminoids also has anti-oxidative, anti-tumoral, anti-microbial and choleretic action.
Indications
- Rheumatoid arthritis
- Osteoarthritis
- Traumatic swelling and pain
- Dental plaque
- Cancer-associated pain or inflammation
Therapeutic class
Herbal and Nutraceuticals
Pharmacological class
Herbal Supplement (Curcumin)
Pharmacology
Curcuminoids is the yellow pigment of Curcuma longa and has long traditional medicinal use in gastric ulcers and dyspepsia. Modern cellular studies on Curcuminoids with almost 4000 pre-clinical investigations, prove it as one of the best studied natural products of the whole biomedical literature. Curcuminoids is known as a master switch of addressing the natural inflammatory response function by down regulating the expression of a series of cytokines, enzymes and transcription factors. It significantly reduces the expression of COX-2, TNF-α, IL-1β, IL-1RN and IL-6 and inhibits the formation of prostaglandin.
Mechanism of action
Curcuminoids regulates inflammatory response by reducing the expression of COX-2, TNF-α, IL-1β, IL-1RN and IL-6 and inhibiting prostaglandin formation.
Dosage
Dosage: 1-2 tablets daily after meal or as directed by physician.
Administration
Take 1-2 tablets daily after meal or as directed by physician.
Missed dose
If you miss a dose of Curcuminoids, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose. Do not double the dose.
Side effects
Well tolerated in recommended dose. Occasionally gastrointestinal disturbance may occur with overdose.
Precautions & warnings
- Consult a physician before starting any new supplement.
- Not recommended during pregnancy.
- Do not use in case of gallstones without consulting a physician.
- Do not exceed the recommended dose.
Contraindications
- Hypersensitivity to curcuminoids
- Obstruction of bile passages
- Gallstones (without physician consultation)
Drug interactions
No significant drug interactions are known.
Food interactions
Can be taken with or without food (recommended after meals).
Use in pregnancy
Not recommended during pregnancy.
Use in lactation
No known restrictions during lactation.
Pediatric use
Pediatric dosage should be determined by a physician.
Geriatric use
Limited information is available regarding dose adjustment for elderly patients.
Renal / hepatic impairment
Caution in obstruction of bile passages or gallstones.
Overdose effects
Information on overdosage is not available. Consult a physician if overdose is suspected.
Storage conditions
Store in a cool and dry place, away from light & moisture. Keep out of reach of children.
Chemical structure
Curcuminoids (Curcuma longa)