Deflazacort

Deflazacort belongs to a group of medicines called steroids. It is used for treatment of various diseases and conditions such as allergic conditions, asthma, cancer, rheumatic disorder, and skin and eye disorders. Deflazacort works by inhibiting the release of substances that cause swelling or by changing how the immune system works. It can be taken in an empty stomach or after food. Taking the medicine regularly at the right times increases its effectiveness. It is important to keep taking the medicine regularly until your doctor tells you it is safe to stop. Taking this medicine can cause few common side effects such as increased appetite, frequent urge to urinate, facial swelling, and abnormal hair growth. If any of these side effects bothers you, let your doctor know. Deflazacort can make it harder for you to fight off infections. Tell your doctor if you have any signs of infection such as a fever or sore throat. Before taking the medicine, you should let your doctor know of all the other medicines you are taking. Pregnant and breastfeeding women should consult their doctors before taking the medicine. .

• Severe allergic reactions • Allergic conditions • Asthma • Cancer • Rheumatic disorder • Skin disorders • Eye disorders

Deflazacort, derived from prednisolone, is a corticosteroid with mainly glucocorticoid activity. An anti-inflammatory dose of 6 mg deflazacort is equiv to 5 mg prednisolone.

Adult Dose: Oral Allergic and inflammatory disorders Adult: Initially, up to 120 mg daily. Maintenance: 3-18 mg/day. Hepatic impairment: Dose reductions may be needed. Child Dose: Oral Allergic and inflammatory disorders Child: 0.25-1.5 mg/kg/day given on alternate days.

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Deflazacort may be taken with or without food, but it is better to take it at a fixed time.

Common: • Increased appetite • Frequent urge to urinate • Facial swelling • Abnormal hair growth • Cushing syndrome • Cough

[SAFE] Deflazacort does not usually affect your ability to drive. Deflazacort helps treat inflammation, severe allergies, flare-ups of ongoing illnesses, and many other medical problems that require either reduction of inflammation or suppression of the immune system. Do not use it more often or for longer than advised by your doctor. Take it with food to avoid an upset stomach. Deflazacort can make it harder for you to fight off infections. Notify your doctor if you have any signs of infection such as a fever or sore throat. Side effects such as mood changes or stomach problems can happen when you start taking Deflazacort. Inform your doctor if this bothers you. Do not stop taking Deflazacort suddenly without talking to your doctor first as it may worsen your symptoms.

Systemic infection; live virus vaccines in those receiving immunosuppressive doses.

Antacids, ACE inhibitors, acetazolamide, adrenergic neuron blockers, antidiabetics, aspirin, barbiturate, ?-blockers, calcium-channel blockers, carbamazepine, carbenoxolone, cardiac glycosides, clonidine, coumarins, diazoxide, diuretics, erythromycin, hydralazine, ketoconazole, methotrexate, methyldopa, mifepristone, minoxidil, moxonidine, nitrates, nitroprusside, NSAIDs, oestrogens, phenytoin, primidone, rifamycins, ritonavir, somatropin, ?2 sympathomimetics, theophylline, vaccines.

[UNSAFE] It is unsafe to consume alcohol with Deflazacort.

[CONSULT YOUR DOCTOR] Deflazacort may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

[CONSULT YOUR DOCTOR] Deflazacort is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

[SAFE IF PRESCRIBED] Deflazacort is safe to use in patients with kidney disease. No dose adjustment of Deflazacort is recommended. However, inform your doctor if you have any kidney disease. [CAUTION] Deflazacort should be used with caution in patients with severe liver disease. Dose adjustment of Deflazacort may be needed. Please consult your doctor. Limited information is available on the use of Deflazacort in these patients.

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