Generic
Flaxseed Oil (Linum Usitatissimum)
2 brands available in the market
At a glance
Flaxseed Oil (Linum Usitatissimum) is a herbal supplement used for hyperlipidemia, constipation, and heart disease. It helps lower cholesterol and reduce inflammation.
Description
Flaxseed is the seed from the plant Linum usitatissimum. Oil from the seed is used to make medicine. People try flaxseed oil for many different conditions especially, high cholesterol, heart disease and constipation. Flaxseed oil is also applied to the skin to soothe irritations or soften roughness and used as dietary supplements.
Flaxseed Oil contains Alpha Linolenic Acid (ALA) which contributes to the maintenance of normal blood cholesterol levels. By increasing HDL level Flaxseed Oil helps to reduce hyperlipidemia. Moreover ALA helps to reduce inflammation.
Indications
- Hyperlipidemia: Used for treatment of high cholesterol and triglycerides.
- Constipation: Used for relief of constipation.
- Heart Disease Prevention: Used to support cardiovascular health.
Therapeutic class
Herbal and Nutraceuticals, Prostaglandin analogues
Pharmacological class
Omega-3 Fatty Acid Supplement
Pharmacology
Flaxseed Oil contains Alpha Linolenic Acid (ALA) which contributes to the maintenance of normal blood cholesterol levels. By increasing HDL level Flaxseed Oil helps to reduce hyperlipidemia. Moreover ALA helps to reduce inflammation. Flaxseed Oil reduces cholesterol levels by increasing prostaglandins E1 and E3 (PGE1 and PGE3), which inhibit cholesterol synthesis and stimulate cholesterol movement across cell membranes.
Mechanism of action
Flaxseed Oil increases prostaglandins E1 and E3 to inhibit cholesterol synthesis and acts as a lubricant in the bowel to relieve constipation.
Dosage
Adult Dose:
- One softgel capsule two to three times daily, with a meal.
- For easier swallowing, take with water before and during ingestion.
Administration
Take this medicine in the dose and duration as advised by your doctor; it is better to take with meals.
Missed dose
If you miss a dose, take it as soon as possible; however, if it is almost time for your next dose, skip the missed dose.
Side effects
Side Effects: Adverse effects are rare at recommended dosages; overdose may cause loose stool and abdominal pain.
Precautions & warnings
Precautions:
- Caution when combined with blood thinning medication (Warfarin, Coumadin) - risk of bleeding.
- Keep out of reach of children.
Contraindications
Contraindications: No known contraindications (caution with blood thinning medications).
Drug interactions
Drug Interactions:
- Blood thinning medication (Warfarin, Coumadin): May increase risk of bleeding; caution required.
Food interactions
Food Interactions: Better to take with meals; caution with alcohol.
Use in pregnancy
Use in Pregnancy: Flaxseed oil might increase the chance of premature birth when taken during the second or third trimesters; caution required.
Pregnancy Category: N/A — always consult a doctor before taking during pregnancy.
Use in lactation
Use in Lactation: Sufficient data not available for use during lactation; consult your doctor.
Pediatric use
Pediatric Use: Flaxseed is possibly safe for children in short-term.
Geriatric use
Geriatric Use: No specific dosage adjustment is necessary for elderly patients.
Renal / hepatic impairment
Renal Impairment: Safe for patients with kidney disease.
Hepatic Impairment: Safe for patients with liver disease.
Overdose effects
Overdose: Overdose may cause loose stool and abdominal pain; symptomatic treatment.
Storage conditions
Storage: Store below 30 degree C, protect from light and moisture. Keep out of reach of children.
Chemical structure
Flaxseed Oil (Linum Usitatissimum)