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Fluorescein Sodium 2% Eye prep

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At a glance

Fluorescein Sodium 2% Eye prep is used for diagnostic ophthalmic procedures and fitting of hard contact lenses.

Description

Fluorescein Sodium 2% Eye prep is used for diagnostic ophthalmic procedures and fitting of hard contact lenses. It acts as a diagnostic staining agent to identify damaged areas on the surface of the eye.

Fluorescein, a precursor of the eosins, temporarily stains any cell it enters therefore marking any damaged areas. It is widely used in ophthalmology to detect corneal abrasions, ulcers, and other surface defects.

Indications
  • Hard Contact Lens Fitting: Used to ensure proper fitting of hard contact lenses.
  • Diagnostic Ophthalmic Procedures: Used for diagnostic staining to detect corneal abrasions, ulcers, and other surface defects.
Therapeutic class

Diagnostic Ophthalmic Preparation

Pharmacological class

Diagnostic Staining Agent

Pharmacology

Fluorescein, a precursor of the eosins, temporarily stains any cell it enters therefore marking any damaged areas. It stains corneal surface cells that have lost their integrity, allowing detection of corneal abrasions, ulcers, and other defects.

Mechanism of action

Fluorescein enters damaged corneal cells and stains them, helping to detect corneal defects during diagnostic examinations.

Dosage

Adult Dose (Ophthalmic):

  • Diagnostic staining: Moisten by applying 1-2 drops on to the eye.
Administration

Apply 1-2 drops to the eye for diagnostic staining.

Missed dose

If you miss a dose of Fluorescein Sodium 2% Eye prep, please consult your ophthalmologist.

Side effects

Side Effects:

  • Transient yellow coloration of skin and urine
  • Staining of the skin, clothing and soft contact lenses

Serious Side Effects: Severe local tissue damage, including phlebitis, skin sloughing, toxic neuritis (from extravasation).

Precautions & warnings

Precautions:

  • Severe local tissue damage may occur from extravasation; use caution; discontinue immediately if extravasation occurs.
  • Transient yellow coloration of skin and urine is normal and harmless.
  • Caution to avoid staining clothing and contact lenses.
Contraindications

Contraindications:

  • Hypersensitivity to components or mercury-containing compounds
  • History of hypersensitivity to fluorescein sodium
Drug interactions

Drug Interactions: No significant interactions known.

Food interactions

Food Interactions: No interaction found/established.

Use in pregnancy

Use in Pregnancy: Category C; limited data on use during pregnancy; consult your doctor.

Pregnancy Category: C — always consult a doctor before taking during pregnancy.

Use in lactation

Use in Lactation: Excreted into breast milk; American Academy of Pediatrics classifies fluorescein as compatible with breast-feeding.

Pediatric use

Pediatric Use: No specific dosage adjustment is necessary; use under medical advice.

Geriatric use

Geriatric Use: No specific dosage adjustment is necessary for elderly patients.

Renal / hepatic impairment

Renal Impairment: No specific precautions necessary (minimal systemic absorption due to topical use).

Hepatic Impairment: No specific precautions necessary (minimal systemic absorption due to topical use).

Overdose effects

Overdose: Limited information on topical overdose; excessive use may cause eye irritation.

Storage conditions

Storage: Store in a cool and dry place, protected from light. Keep out of reach of children.

Chemical structure

Fluorescein Sodium 2% Eye prep

Common questions

Q1: What is Fluorescein eye drop used for?
It is used for hard contact lens fitting and diagnostic ophthalmic procedures to detect corneal defects.
Q2: What are the side effects of Fluorescein?
Transient yellow coloration of skin and urine, staining of skin and clothing.
Q3: Can it be used during pregnancy?
Category C; consult your doctor.
Q4: Can it be used during breastfeeding?
Excreted into breast milk; AAP classifies as compatible with breast-feeding.
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.