Flurbiprofen

Flurbiprofen is a pain relieving medicine. It is used to treat pain, swelling, and stiffness caused by conditions such as osteoarthritis and rheumatoid arthritis. Flurbiprofen is only meant for external use and should be used strictly as advised by your doctor. A thin layer of the medicine should be massaged into the affected areas with clean and dry hands. Avoid getting in contact with your eyes, nose, or mouth and avoid applying it on wounded or damaged skin. In case of accidental contact, you should rinse it thoroughly with plenty of water. It is usually safe with little or no side effects. However, it may cause burning sensation and skin irritation at the site of application in some people. They are usually temporary and resolve with time. If they do not get better with time or worsen, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the symptoms. Before using the medicine, it is important to tell your doctor if you are using or have recently used any other medicines for the same disease or other diseases. To make sure the medicine is safe, pregnant and breastfeeding women should consult their doctor before using the medicine.

• Pain relief

Flurbiprofen is a non-steroidal anti-inflammatory drug (NSAID). It works by blocking the release of certain chemical messengers that cause fever, pain and inflammation (redness and swelling).

Adult Dose: Oral Pain and inflammation Adult: 150-200 mg daily in divided doses, increased to 300 mg daily in acute or severe conditions if necessary. Dysmenorrhoea Adult: Initially, 100 mg followed by 50-100 mg 4-6 hrly. Max: 300 mg daily. Rheumatoid Arthritis, Osteoarthritis 200-300 mg/day divided q6-12hr PO, not to exceed 100 mg/dose or 300 mg/day Child Dose: <12 years: Not recommended Renal Dose: Renal Impairment Severe Impairment: Not recommended

This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the gel. Wash your hands after applying, unless hands are the affected area.

Common: • No common side effects seen

No interaction found/established You have been prescribed Flurbiprofen to relieve pain and inflammation.

Peptic ulcer, GI haemorrhage, asthma, bronchospasm, rhinitis, angioedema, hypersensitivity; aspirin intolerance; pregnancy (3rd trimester); lactation.

Reduced antihypertensive effect of ACE inhibitors, angiotensin II receptor antagonists and ?-blockers. Slight reduction in blood glucose concentration in patients w/ DM receiving certain antidiabetic agents (e.g. glyburide, metformin). Reduced diuretic effect of furosemide and thiazides. May increase toxicity of lithium and methotrexate. May increase risk of bleeding w/ antiplatelets, anticoagulants, SSRIs, corticosteroids.

No interaction found/established

[CONSULT YOUR DOCTOR] Flurbiprofen may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

[SAFE IF PRESCRIBED] Flurbiprofen is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.

No interaction found/established No interaction found/established

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