Generic
Glutaraldehyde
1 brands available in the market
At a glance
Glutaraldehyde is a disinfectant used to sterilize medical and dental equipment.
Description
Introduction: Glutaraldehyde is a pungent colorless oily liquid, used to disinfect medical and dental equipment. It is also used for industrial water treatment and as a chemical preservative.
How it works: Glutaraldehyde is a bactericidal disinfectant which is rapidly effective against gram positive and gram-negative bacteria, viruses including HBV, HIV, fungi and spores.
Important Information: Can be used as sterilant at 25°C with 10 hours immersion and as high level disinfectant with 45 minutes immersion. Can be reused for up to maximum 14 days.
Indications
- Sterilant: At 25°C with immersion time of at least 10 hours
- High Level Disinfectant: At 25°C with immersion time of at least 45 minutes
Therapeutic class
Disinfectant Preparations
Pharmacological class
Aldehyde Disinfectant
Pharmacology
Glutaraldehyde is a pungent colorless oily liquid, used to disinfect medical and dental equipment. It is also used for industrial water treatment and as a chemical preservative. Glutaraldehyde is a bactericidal disinfectant which is rapidly effective against gram positive and gram-negative bacteria, viruses including HBV, HIV, fungi and spores.
Mechanism of action
Glutaraldehyde acts on proteins and nucleic acids of bacteria and viruses to disrupt their cellular activity.
Dosage
Usage Procedure:
- Clean, rinse and rough dry devices before immersing
- Completely immerse medical devices in Glutaraldehyde Solution, filling all lumens
- Leave completely immersed for required time at 15°-30°C
- Sterilant: At 25°C with at least 10 hours immersion
- High Level Disinfectant: At 25°C with at least 45 minutes immersion
Activation: Add entire contents of Activator Vial, shake well
Reuse Period: Maximum 14 days
Administration
For professional use only. After activation, solution turns green. Record date of activation in logbook.
Missed dose
If you miss a dose, follow usage instructions.
Side effects
Toxicity (Ingestion):
- Intense pain
- Inflammation, ulceration and necrosis of mucous membranes
- Vomiting, haematemesis
- Blood-stained diarrhea
- Haematuria, anuria
- Metabolic acidosis
- Vertigo, convulsion
- Loss of consciousness and circulatory failure
Precautions & warnings
Precautions:
- Avoid gastric lavage and emesis
- Give milk, water, charcoal or demulcents for prevention of absorption
- Assisted ventilation if indicated
- Acidosis may require IV sodium bicarbonate or sodium lactate
Contraindications
Contraindications:
- No specific contraindications, but avoid if hypersensitive to glutaraldehyde
Drug interactions
Drug Interactions: No significant interactions known.
Food interactions
Food Interactions: Not applicable.
Use in pregnancy
Use in Pregnancy: Avoid occupational exposure. Use protective measures if necessary.
Pregnancy Category: NA — always consult a doctor before taking during pregnancy.
Use in lactation
Use in Lactation: Avoid occupational exposure. Use protective measures if necessary.
Pediatric use
Pediatric Use: Not applicable (for professional use).
Geriatric use
Geriatric Use: Not applicable (for professional use).
Renal / hepatic impairment
Renal & Hepatic Impairment: Not applicable (for professional use).
Overdose effects
Overdose: If ingested, seek immediate medical attention. Avoid gastric lavage and emesis.
Storage conditions
Storage: Store within temperature 15°-25°C and protect from sunlight.
Chemical structure
Glutaraldehyde Solution