Hartmann's Solution

Introduction: Hartmann's Solution is a sterile electrolyte solution containing Sodium Chloride, Potassium Chloride, Calcium Chloride and Sodium Lactate. It is used to treat hypovolemia caused by surgery, hemorrhage and trauma, and dehydration.

How it works: This solution restores fluid and electrolyte balance, increases blood volume and helps treat metabolic acidosis associated with dehydration.

Important Information: The volume and rate of infusion depend on the patient's age, weight and clinical condition. For burn patients, the Parkland formula is used.

• Hypovolemia: caused by surgery, hemorrhage and trauma
• Dehydration: due to excessive sweating, severe diarrhea or vomiting, excess fluid loss by kidneys
• Plasma loss: caused by intestinal obstruction, burns or denuding skin conditions
• Metabolic acidosis: associated with dehydration (alternative to Sodium Bicarbonate)
• Alkalinized urine

Haemodialysis solutions

Electrolyte Solution

Hartmann's Solution is a sterile solution of Sodium Chloride, Potassium Chloride, Calcium Chloride and Sodium Lactate. Each litre contains Sodium 131 mmol, Potassium 5 mmol, Calcium 2 mmol, Bicarbonate (as lactate) 29 mmol, and Chloride 111 mmol. It restores fluid and electrolyte balance, increases blood volume and helps treat metabolic acidosis associated with dehydration.

Hartmann's Solution replenishes fluid and electrolyte deficits and restores blood volume.

Adult Dose:

• Recommended flow rate: up to 100 drops/minute/70 kg body weight
• Burn patients (Parkland formula): 4 ml/kg × % BSA burn (over 24 hours)
• Example: 60 kg with 30% BSA burn = 7200 ml/24 hours (half in first 8 hours)

Intravenous (IV) infusion. Check infusion set and solution prior to use. Do not use if the solution is cloudy, contains particles, or after expiry date.

If you miss a dose, consult your doctor.

Common Side Effects:

• Mild swelling of hands, ankles and feet (fluid retention)
• Rare: fluid in lungs causing breathing difficulty
• Nausea, vomiting
• Headache, dizziness
• Drowsiness, confusion
• Inflammation or swelling of veins around injection site

Precautions:

• Should not be administered rapidly or for prolonged periods
• Use with caution in pregnancy, renal impairment, heart failure, pulmonary congestion
• Caution in patients receiving potassium sparing diuretics
• Discontinue if rigor arises during infusion
• Caution in diabetes mellitus (one isomer of lactate is gluconeogenic)

Contraindications:

• Severe hyperkalemia
• Severe hypernatremia
• Severe hyperchloremia
• Diabetes mellitus - caution required (due to lactate)

Drug Interactions:

• Caution with potassium-sparing diuretics

Food Interactions: Not applicable (intravenous administration).

Use in Pregnancy: Pregnancy Category C. Use only if clearly needed.

Use in Lactation: Safe to use during breastfeeding.

Pediatric Use: Dose is individualized based on age, weight and clinical condition.

Geriatric Use: Dose is individualized considering heart and kidney function.

Renal Impairment: Use with caution in renal impairment.

Hepatic Impairment: Use with caution in liver disease (lactate metabolism occurs in liver).

Overdose: Fluid and electrolyte overload may occur. Heart failure, pulmonary edema may occur - discontinue infusion and provide supportive care.

Storage: Store at controlled room temperature.

Hartmann's Solution (Electrolyte Solution)