Generic
Iron Polymaltose Complex
4 brands available in the market
At a glance
Iron Polymaltose Complex syrup is used for the treatment of latent iron deficiency and iron deficiency anaemia including macrocytic anaemia, nutritional anaemia of infants, anaemia due to excessive haemorrhage and anaemia associated with infections and malignant disease.
Description
Iron Polymaltose Complex is a polysaccharide-iron complex, which is a novel iron preparation used in the treatment of iron deficiency anaemia. It contains non-ionic ferric iron and polymaltose in a stable complex that facilitates controlled absorption of ferric iron when it comes in contact with mucosal cell surface. Being non-ionic, it does not interact with food components and other medications, so bioavailability is not decreased.
Indications
- Latent iron deficiency
- Iron deficiency anaemia (macrocytic anaemia, nutritional anaemia of infants, anaemia due to excessive haemorrhage, anaemia associated with infections and malignant disease)
- Prevention and treatment of iron deficiency anaemia before, during and after pregnancy and during lactation
Therapeutic class
Oral Iron preparations
Pharmacological class
Iron Polymaltose Complex
Pharmacology
Iron Polymaltose Complex is a polysaccharide-iron complex, which is a novel iron preparation used in the treatment of iron deficiency anaemia. It contains non-ionic ferric iron and polymaltose in a stable complex. This complex facilitates a controlled absorption of the ferric iron when it comes in contact with the mucosal cell surface. Being non-ionic, it does not interact with food components and other medications, so bioavailability is not decreased.
Mechanism of action
Iron Polymaltose Complex facilitates controlled iron absorption and ensures faster utilization in haemoglobin and myoglobin synthesis to correct iron deficiency.
Dosage
Adult Dose (Oral):
- 10 ml once or twice daily
Child Dose (Oral):
- 6-12 years: 10 ml daily
- 2-6 years: 5 ml daily
- Premature infants & Infants: 3.33 mg elemental iron/kg body weight
Administration
Take in the dose and duration as advised by your doctor; measure with a measuring cup; take on empty stomach.
Missed dose
If you miss a dose, please consult your doctor.
Side effects
Side Effects:
- Nausea
- Vomiting
- Constipation
- Diarrhea
Precautions & warnings
Precautions:
- Caution in conditions where there is a risk of iron overload (haemochromatosis, thalassemia or haemosiderosis)
- Caution in hypersensitivity to iron or any other ingredients
Contraindications
Contraindications:
- Haemochromatosis, thalassemia or haemosiderosis
- Hypersensitivity to iron or any other ingredients
Drug interactions
Generally no interactions have been observed; since iron is complex bound, ionic interactions with foodstuff components (phytates, oxalates, tannin) and concomitantly administered medicaments (tetracycline, antacids) are unlikely.
Food interactions
No food interaction found/established.
Use in pregnancy
Use in Pregnancy: Administration during first trimester requires careful assessment of potential risk versus benefits; should not be administered unless clearly indicated; iron therapy may be indicated for remainder of pregnancy on physician advice.
Use in lactation
Use in Lactation: Iron is excreted in breast milk but not in clinically significant concentrations.
Pediatric use
Recommended in children; doses provided above.
Geriatric use
No specific data for elderly; however caution advised.
Renal / hepatic impairment
Renal Impairment: No specific precautions; however consult your doctor.
Hepatic Impairment: Avoid higher doses if you have liver disease or hemochromatosis.
Overdose effects
Overdose: Initially epigastric pain, diarrhea and vomiting; may include metabolic acidosis, convulsions, and coma after apparent recovery; seek emergency medical attention; initially give emetic, followed by gastric lavage with 1% sodium bicarbonate, and oral administration of desferrioxamine.
Storage conditions
Keep below 30°C temperature, away from light & moisture; keep out of reach of children.
Chemical structure
Iron Polymaltose Complex