Generic
Levosalbutamol
78 brands available in the market
At a glance
Levosalbutamol is a fast-acting bronchodilator or reliever used to relieve symptoms of asthma and COPD such as coughing, wheezing, shortness of breath, and chest tightness.
Description
Levosalbutamol is a single isomer beta-2 agonist that differs from racemic salbutamol by elimination of (S)-salbutamol. It produces bronchodilatation through stimulation of beta-2-adrenergic receptors in bronchial smooth muscles, causing relaxation of bronchial muscle fibres.
Indications
- Asthma
- Chronic Obstructive Pulmonary Disease (COPD)
Therapeutic class
Bronchodilator
Pharmacological class
Beta-2 Agonist
Pharmacology
Levosalbutamol stimulates beta-2-adrenergic receptors in bronchial smooth muscles, causing relaxation of bronchial muscle fibres and bronchodilatation, making breathing easier.
Mechanism of action
Relaxes airway muscles, widens airways, and makes breathing easier.
Dosage
Oral (Adult): 1-2 mg, three times daily
Inhaler: 1-2 puffs as required
Nebuliser (Adult): 0.63 mg, 3-4 times daily (every 6-8 hours); severe asthma: 1.25 mg three times daily
Children (6-11 years): 5 mL (1 mg), three times daily
Children (2-5 years): Up to 0.1 mg/kg (max 1 mg), three times daily
Administration
- Check label for directions before use
- Shake the inhaler before use
- Press down on the inhaler while breathing in and hold breath for 10 seconds
- Rinse mouth thoroughly with water after use
Missed dose
If you miss a dose, skip it and continue with your normal schedule. Do not double the dose.
Side effects
Common Side Effects:
- Throat pain
- Nasal congestion
- Dizziness
- Vomiting
Precautions & warnings
- If you need to use more than 3 times a week, inform your doctor (asthma is not well controlled)
- Inform your doctor if you have a history of heart disease
- Caution when driving or activities requiring concentration (may cause dizziness or tremor)
- Avoid alcohol
Contraindications
- Hypersensitivity to Levosalbutamol or any of its components
Drug interactions
No significant drug interactions known.
Food interactions
Levosalbutamol may cause excessive drowsiness with alcohol.
Use in pregnancy
Use in Pregnancy: Levosalbutamol may be unsafe during pregnancy; animal studies have shown harmful effects on the fetus. Consult your doctor.
Use in lactation
Use in Lactation: Levosalbutamol is safe during breastfeeding; does not pass into breastmilk in significant amounts.
Pediatric use
Pediatric doses are established (age and weight-based).
Geriatric use
No dose adjustment may be needed in elderly.
Renal / hepatic impairment
No specific precautions applicable.
Overdose effects
No specific overdose information available; symptomatic and supportive measures should be employed.
Storage conditions
Store in a cool and dry place; keep out of reach of children.
Chemical structure
Levosalbutamol