Nutryelt Injection is a iv infusion manufactured by ZAS Corporation in Bangladesh. Its active ingredient is Mix of 9 Trace Elements.

Indications

NUTRYELT is used as part of an intravenous nutrition regimen, to cover basal or moderately increased trace element requirements in parenteral nutrition.
NUTRYELT is indicated for adults only.
Gastrointestinal disorders (e.g., short bowel syndrome, Crohn’s disease)
Post-operative recovery when oral intake is not feasible
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NUTRYELT is used as part of an intravenous nutrition regimen, to cover basal or moderately increased trace element requirements in parenteral nutrition.
NUTRYELT is indicated for adults only.
Gastrointestinal disorders (e.g., short bowel syndrome, Crohn’s disease)
Post-operative recovery when oral intake is not feasible
Cancer patients undergoing chemotherapy or radiation therapy, with disrupted digestive function
Neurological conditions where oral or enteral feeding is not possible
Burns, trauma, or sepsis requiring nutritional support

Contraindications

Children or patients <40kg
Severe cholestasis (bilirubin levels>140 µmol/l)
Hypersensitivity to one of the active substances or to the excipient
Wilson's diseases
Hemochromatosis
Elevated serum concentrations of any of the NUTRYELT constituents

Composition

Each 10 ml vial contains-
Ferrous gluconate: Iron (Fe): 1 mg
Zinc gluconate: Zinc (Zn): 10 mg
Copper gluconate: Copper (Cu): 0.30 mg
Manganese gluconate: Manganese (Mn): 0.055 mg
Sodium fluoride: Fluorine (F): 0.95 mg
Cobalt (Co): 0.30 mg
Potassium iodide: Iodine (I): 130 µg
Sodium selenite: Selenium (Se): 70 µg
Sodium molybdate: Molybdenum (Mo): 20 µg
Chromic chloride: Chromium (Cr): 10 µg

Pharmacology

A balanced parenteral nutrition (PN) multi-trace element solution containing nine essential trace elements that helps avoid micronutrient deficiencies and aligns with international guidelines. NUTRYELT is a parenteral nutrition solution, meaning it provides essential nutrients directly into the bloodstream, bypassing the gastrointestinal system. The nutrients in NUTRYELT are metabolized by the body to provide:

Energy through glucose.

Protein synthesis and tissue repair via amino acids.

Cellular structure and function via lipids and fatty acids.

Metabolic regulation and maintenance of physiological functions through vitamins, minerals, and electrolytes.

NUTRYELT supports vital physiological processes such as immune function, cellular repair, and the generation of energy from stored nutrients.

Dosage & Administration

Patients with baseline or moderately increased requirements: 1 ampoule (10 ml) of NUTRYELT/day

Patients with significantly increased TE requirements: 2 ampoules (20 ml) of NUTRYELT/day

Diluted in an infusion solution of 250 ml 0.9% NaCl or 250 ml 5 % of glucose or added to PN mixtures

After dilution, the physico chemical stability of the diluted solution has been demonstrated for 48 hours at 25°C protected from light.

Interaction

Drug interactions: Parenteral nutrition may interact with certain medications, particularly those that affect the metabolism of nutrients (e.g., insulin for glucose control, diuretics for electrolyte balance).

Electrolyte imbalances: Medications that impact kidney or liver function may also affect electrolyte balance, which can be managed with careful monitoring.

Side Effects

Hyperglycemia (high blood sugar) due to the glucose content.
Electrolyte imbalances: Changes in sodium, potassium, or calcium levels.
Infections: Due to the intravenous administration route.
Liver dysfunction or fatty liver, particularly with prolonged use.
Thrombophlebitis (inflammation of veins) at the injection site.
Gastrointestinal issues: If transitioning back to enteral feeding, nausea or diarrhea may occur

Pregnancy & Lactation

Parenteral nutrition should be used cautiously during pregnancy. The benefits and risks need to be carefully evaluated, as malnutrition and electrolyte disturbances in the mother could affect fetal development. If necessary, it should be administered under medical supervision.

Precautions & Warnings

Monitoring required: Regular monitoring of blood glucose, electrolytes, and liver function is essential.

Infection risk: Since the solution is administered intravenously, aseptic techniques must be followed rigorously to avoid infections.

Fluid overload: Caution should be exercised in patients with compromised renal function or heart failure.

Therapeutic Class

Parenteral nutritional preparations

Storage Conditions

Protected from light, temperature below 25°C.

Disclaimer: This information is for reference only. Always consult a registered physician before taking any medicine.

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